DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5R2 and pts1

DIOPT Version :9

Sequence 1:	NP_001286022.1	Gene:	Prosbeta5R2 / 318924	FlyBaseID:	FBgn0051742	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_593825.1	Gene:	pts1 / 2543623	PomBaseID:	SPAC4A8.13c	Length:	272	Species:	Schizosaccharomyces pombe

Alignment Length:	246	Identity:	115/246 - (46%)
Similarity:	155/246 - (63%)	Gaps:	13/246 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SSNMDNPLAIMAPP-YEN-------PRESVKKLNALSEVQ-----IDFDHGTTTVGFVYQGGIIL 85
            |:|.|:|..|:... :.|       |:.|:...|...|.:     |..:|||||:.|.||.||::
pombe    11 STNNDDPKKIIEEEGFTNRFDVVPVPQSSLYLRNLTDETKNKHCLIKMNHGTTTLAFRYQHGIVV 75

  Fly    86 CVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLPVQSA 150
            ||||||::|.||.||::.||:::|.|::||.|||||||.:|:..|..|||||:||.||.:.|.:|
pombe    76 CVDSRASAGPLIASQTVKKVIEINPYLLGTLAGGAADCQFWETVLGMECRLHQLRNKELISVSAA 140

  Fly   151 AKYISNVAAEYKGMGLCMGMMLAGWSPEGPSLVYVDSNGLRIHGKLFAVGSGAPNALGILDSDYR 215
            :|.:||:...|||.||.||.||||....|.:|.|:||:|.|:.|.||:||||:..|.|:|||.||
pombe   141 SKILSNITYSYKGYGLSMGTMLAGTGKGGTALYYIDSDGTRLKGDLFSVGSGSTFAYGVLDSGYR 205

  Fly   216 LDLSDNEAYDLAFLAVYHATMTDIFSGGVVRLYHMDQGNWRNVANKDCQEL 266
            .|||..||..||..::..||..|.:|||.|.|||:|:..|....|.|...|
pombe   206 WDLSKQEALYLAQRSIVAATHRDAYSGGSVNLYHIDENGWVFHGNFDVDSL 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_001286022.1	PTZ00488	46..279	CDD:185666	110/234 (47%)
Prosbeta5R2	NP_001286022.1	proteasome_beta_type_5	72..259	CDD:239730	99/186 (53%)
pts1	NP_593825.1	PRE1	39..262	CDD:223711	108/218 (50%)
pts1	NP_593825.1	proteasome_beta_type_5	62..249	CDD:239730	99/186 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	258	1.000	Inparanoid score	I755
OMA	1	1.010	-	-		QHG53702
OrthoFinder	1	1.000	-	-		FOG0001305
OrthoInspector	1	1.000	-	-		otm47067
orthoMCL	1	0.900	-	-		OOG6_100897
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X647
TreeFam	1	0.960	-	-
	11	10.830