DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5R2 and pbs-5

DIOPT Version :9

Sequence 1:	NP_001286022.1	Gene:	Prosbeta5R2 / 318924	FlyBaseID:	FBgn0051742	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_493558.1	Gene:	pbs-5 / 173334	WormBaseID:	WBGene00003951	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	192	Identity:	86/192 - (44%)
Similarity:	123/192 - (64%)	Gaps:	7/192 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 IDFDHGTTTVGFVYQ-------GGIILCVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGAADC 123
            :.|..||||:.|||:       ||||:.|||||:||:.|.|:|:.|::.:...::.|.|||||||
Worm    59 MQFRKGTTTLAFVYEPATPADKGGIIVAVDSRASSGEYISSKSVMKILDIGDRMVATMAGGAADC 123

  Fly   124 TYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSPEGPSLVYVDSN 188
            .:|.|.:.:.|.|:|||.|..:.|.:|:||.:|....|:|.||.:|.|:||:..:||.:..|||.
Worm   124 QFWTRIVAKYCTLYELREKTSITVSAASKYFANTLYGYRGQGLSVGSMVAGYDKKGPQIFKVDSE 188

  Fly   189 GLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMTDIFSGGVVRLYHM 250
            |.|...|:.:||||:.||.||||:.|:..::|:||..|...|:.|||..|..||||..|.|:
Worm   189 GDRCQLKVCSVGSGSLNAYGILDNHYKPKMTDDEARKLGLRAIMHATYRDSGSGGVCNLCHI 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_001286022.1	PTZ00488	46..279	CDD:185666	86/192 (45%)
Prosbeta5R2	NP_001286022.1	proteasome_beta_type_5	72..259	CDD:239730	84/186 (45%)
pbs-5	NP_493558.1	Ntn_hydrolase	65..252	CDD:320988	84/186 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159082
Domainoid	1	1.000	200	1.000	Domainoid score	I1766
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I2376
Isobase	1	0.950	-	0	Normalized mean entropy	S454
OMA	1	1.010	-	-		QHG53702
OrthoDB	1	1.010	-	-		D396507at33208
OrthoFinder	1	1.000	-	-		FOG0001305
OrthoInspector	1	1.000	-	-		otm14414
orthoMCL	1	0.900	-	-		OOG6_100897
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X647
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.760