DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kdm4B and SNT2

DIOPT Version :9

Sequence 1:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	NP_011384.1	Gene:	SNT2 / 852746	SGDID:	S000003099	Length:	1403	Species:	Saccharomyces cerevisiae

Alignment Length:	218	Identity:	45/218 - (20%)
Similarity:	76/218 - (34%)	Gaps:	76/218 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 FGYHAGFNHGFNCAE-STNFAMERWIEYGKRAVQCT--CSNDMVKISMDTFVKR--FQSDRYDLW 330
            :.||      ..||: |:||.:  ..|....:|..|  |..| ||:: ||:..|  ...||:|:.
Yeast  1197 YRYH------ITCAQNSSNFKL--MFEKKNMSVDTTLPCIKD-VKLN-DTYTLRPILICDRHDIS 1251

  Fly   331 MEGRDVG---------------------------------------RHPEDPPNAVLSAAPLPPH 356
            :||.::.                                       ||.|.|.|:..||  :.|.
Yeast  1252 LEGNELYPLSYKPQHTLSYIEQYCRYYKCESDHSLVELRYFEQLRLRHGEMPGNSHDSA--IKPK 1314

  Fly   357 LDVLLCDKKMKKQCNPTKAK-----------SFKERNPDLDLD----EIQQNPNVPDDVKAMLKE 406
            :.||..::.. ..|...|:.           :.:....:||.|    .|..:..:|.::...|.|
Yeast  1315 IYVLPFERTC-PHCGTNKSLYWYEDIICHSCNLRSGAQELDFDSASANISNDNGLPVEITQQLME 1378

  Fly   407 SV----LTLDTGDLATDEADFPN 425
            .:    ..:|..:..||:...|:
Yeast  1379 GIEPAMFDIDISEAGTDKNTHPS 1401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224	5/18 (28%)
SNT2	NP_011384.1	BAH_fungalPHD	112..256	CDD:240061
		PHD1_Snt2p_like	319..366	CDD:276972
		Myb_DNA-binding	559..602	CDD:395191
		PHD2_Snt2p_like	1040..1094	CDD:276973
		ePHD_Snt2p_like	1108..1248	CDD:277137	18/60 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900