DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4B and JADE1

DIOPT Version :9

Sequence 1:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_024309986.1	Gene:	JADE1 / 79960	HGNCID:	30027	Length:	857	Species:	Homo sapiens

Alignment Length:	153	Identity:	40/153 - (26%)
Similarity:	53/153 - (34%)	Gaps:	38/153 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   487 RNNRGRSPRTKDD-------RSISPASSTSSTSR---GARRGKASGTPRKTPARRKK------DS 535
            |:||......|.|       :|..|..||..:.|   ..|...:.|..:..|..||:      .|
Human   675 RDNRFHCDLIKGDLKDKSFKQSHKPLRSTDVSQRHLDNTRAATSPGVGQSAPGTRKEIVPKCNGS 739

  Fly   536 ITTSPAVSSAATAVKTPTSAVVAGTTSIATTTTPPADGGG---DAKKERQSLQFMQQSRKFEGKI 597
            :.   .|:...||||.||           |..:|..:.||   ..|.|||     ||....:|..
Human   740 LI---KVNYNQTAVKVPT-----------TPASPVKNWGGFRIPKKGERQ-----QQGEAHDGAC 785

  Fly   598 PKLSQTSAATGGATAAAEASTSK 620
            .:.|.......|...|.|.:.||
Human   786 HQHSDYPYLGLGRVPAKERAKSK 808

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224
JADE1	XP_024309986.1	EPL1	114..>544	CDD:331339
JADE1	XP_024309986.1	ePHD_JADE1	270..387	CDD:277174
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900