DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4B and Phf14

DIOPT Version :9

Sequence 1:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_006505259.1	Gene:	Phf14 / 75725	MGIID:	1923539	Length:	946	Species:	Mus musculus

Alignment Length:	215	Identity:	47/215 - (21%)
Similarity:	80/215 - (37%)	Gaps:	34/215 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   353 LPPHLDVLLCDKKMKKQC--NPTKAKSFKERNPDLDLDEIQQNPNVPDDVKAMLKESVLTLDTGD 415
            :|....::..:||.:::.  .|.|.|. ||:..:.:.::.::...|.|...|  ..:..|..|..
Mouse    89 MPSDKQLIKMEKKEEEENGERPRKKKE-KEKEKEKEREKDKEKATVSDSAAA--SAAGTTPATSP 150

  Fly   416 LATDEADFP------NEDAMSLQSPANLKTKQELLEYID----DGTEDDDEEED-------FKRR 463
            .|......|      .|:.:|.....||:..:.||:::.    :..:|.|.|:|       .||:
Mouse   151 PAVTSPSVPTTTTTTTEEQVSEPKKWNLRRNRPLLDFVSMEELNAMDDYDSEDDNDWRPTVVKRK 215

  Fly   464 ----KQKRRYDADYDDDWLASKRKTNSRNNRGRSPRTKDDRSISPASSTSSTSRGARRGKASGTP 524
                .||...|.|.:||...........|:.|     .|:...||||......   :|.|.....
Mouse   216 GRSASQKEGSDGDNEDDDDEGSGSEEDENDEG-----NDEDHSSPASEAGGKK---KRSKVLSRN 272

  Fly   525 RKTPARRKKDSITTSPAVSS 544
            .........||:|.|.:.|:
Mouse   273 SADDEELTNDSLTLSQSKSN 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224
Phf14	XP_006505259.1	PHD1_PHF14	314..370	CDD:277036
		ePHD_PHF14	378..491	CDD:277144
		PHD2_PHF14	720..769	CDD:277037
		PHD3_PHF14	863..911	CDD:277038
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900