Protein Alignment Kdm4B and kdm4b

DIOPT Version :9

• Sequence 1: NP_001260942.1
• Gene: Kdm4B / 318918
• FlyBaseID: FBgn0053182
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001076274.1
• Gene: kdm4b / 556504
• ZFINID: ZDB-GENE-060503-664
• Length: 1134
• Species: Danio rerio
• Alignment Length: 620
• Identity: 273/620 - (44%)
• Similarity: 360/620 - (58%)
• Gaps: 87/620 - (14%)

  Fly     8 RIKVFRPTWEEFKDFPKYVAYMESQGAHKAGLAKVVPPPEWVPRRSGYADLDALNVTIPAPICQV 72
            :|..||||.||||||.||:||||:||||.||||||:||.||.|||| |..::  ::.|||||.||
Zfish    94 KIMTFRPTMEEFKDFGKYIAYMETQGAHVAGLAKVIPPKEWKPRRS-YETIE--DMVIPAPIMQV 155

  Fly    73 VTGKQGYYQQINIQKKPLTVKQFSELASTERYATPKHFDFEDLERKYWKNITYVAPIYGADVSGS 137
            |||:.|.:.|.|||||.:||.::.:||::::|.||:|.||:|||||||||:|:|:||||||:|||
Zfish   156 VTGQSGLFTQYNIQKKSMTVGEYRKLANSKKYNTPQHKDFDDLERKYWKNLTFVSPIYGADISGS 220

  Fly   138 ITDTDQDSWNINRLGTILDYVNKDYNIQIDGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGA 202
            :.|.|...|||..|.|:||.|.::..|.|:||||.|||||||||||||||||||||||||||||.
Zfish   221 LYDPDISEWNIGHLNTLLDMVEQECGIVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGK 285

  Fly   203 PKTWYVVPPECGRKLEKVANQYFPASYKNCNAYLRHKMTLISPQILKQHDVPVSKITQEAGEIMI 267
            ||:||.:|||.|::||::|..:||.|.:.|:|:||||||||||.|||::.:|..:||||.||.||
Zfish   286 PKSWYAIPPEHGKRLERLAQGFFPGSSQGCDAFLRHKMTLISPSILKKYSIPFDRITQEEGEFMI 350

  Fly   268 TFPFGYHAGFNHGFNCAESTNFAMERWIEYGKRAVQCTCSNDMVKISMDTFVKRFQSDRYDLWME 332
            |||:|||||||||||||||||||..|||:|||.|.||||..||||||||.||:|.|.:||..|.:
Zfish   351 TFPYGYHAGFNHGFNCAESTNFATLRWIDYGKMAAQCTCRKDMVKISMDVFVRRLQPERYTQWKQ 415

  Fly   333 GRDVGRHPEDPPNAVLSAAPLPPHLD------VLLCDK-------KMK--KQCNPTKAKSFKERN 382
            |:|........|.::.|     |.|:      |...:|       |||  ::..|...|...|..
Zfish   416 GKDTMVLDHLKPTSLSS-----PELEHWRKNRVTFREKVLRRAQAKMKQFRRLKPEDLKVLMEAG 475

  Fly   383 PDLDLDEIQQNPNVPDDVK------AMLKESVLTLDTGDLATDEADFPNEDAMSLQSPANLKTKQ 441
            .:||::|.|:.....|:.:      .|.:|::|||:.  |..:|           |..|....:.
Zfish   476 VELDMEEYQRKVEEHDEQRRQQRDERMAREAMLTLEA--LEREE-----------QEQAEAALRG 527

  Fly   442 ELLEYIDDGTEDDDEEEDFKRRKQKRRYD-------ADYDDDWLASKRKTNSRNNRG---RSPRT 496
            ..:|.|....:|...|...|::|:|::..       .:..:.:..:....|..|...   .:|.|
Zfish   528 GGVEEIKADFQDPPVENGEKKKKKKKKLQLTDEMSFQEVFEQFTTASEMQNQSNGAAPLQTNPFT 592

  Fly   497 KDDRSISPASSTSSTSRGARRGKASGTPRKTPARRKKDSITTSPAVSSAATAVKTPTSAVVAGTT 561
            |..:.:....|        ||...|..|.::|     .||....|.|........|.
Zfish   593 KLKKKVEVKKS--------RRHPISKPPMRSP-----HSIVKQEASSDEELYSGLPV-------- 636

  Fly   562 SIATTTTPPADGGG---DAKKERQSLQFMQQSRKF 593
                       |||   ::||...|..:..:|..|
Zfish   637 -----------GGGVTHESKKPEDSDLWQNRSPNF 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526	26/32 (81%)
		JmjC	173..289	CDD:202224	86/115 (75%)
kdm4b	NP_001076274.1	JmjN	95..136	CDD:128818	31/40 (78%)
		JmjC	256..372	CDD:202224	86/115 (75%)
		YscO	<408..512	CDD:284686	27/108 (25%)
		PHD_JMJD2B	676..774	CDD:277051
		PHD_SF	783..892	CDD:304600
		TUDOR	905..953	CDD:197660
		tatB	<978..1099	CDD:166942

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	212	1.000	Domainoid score	I2716
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000582
OrthoInspector	1	1.000	-	-		mtm6370
orthoMCL	1	0.900	-	-		OOG6_100918
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2594
SonicParanoid	1	1.000	-	-		X490
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.840