DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4B and Phf14

DIOPT Version :9

Sequence 1:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_006236166.1	Gene:	Phf14 / 500030	RGDID:	1563764	Length:	950	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	50/218 - (22%)
Similarity:	86/218 - (39%)	Gaps:	44/218 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 DVLLCDK---KMKKQ------CNPTKAKSFKERNPDLDLDEIQQNPNVPDDVKAMLKESVLTLDT 413
            :::..||   ||:|:      ..|.|.|. ||:..:.:.::.::...|.|...|  ..:..|..|
  Rat    87 EIMSSDKQLIKMEKKEEEENGERPRKRKE-KEKEKEKEREKDKEKATVSDSAAA--SAAGTTPAT 148

  Fly   414 GDLATDEADFP-----NEDAMSLQSPANLKTKQELLEYID----DGTEDDDEEED-------FKR 462
            ...|......|     :|:.:|.....||:..:.||:::.    :..:|.|.|:|       .||
  Rat   149 SPPAVTSPAVPTTTTSSEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKR 213

  Fly   463 R----KQKRRYDADYDDDWLASKRKTNSRNNRGRSPRTKDDRSISPASSTSSTSRGARRGKASGT 523
            :    .||...|.|.:||...........|:.|     .|:...||||..     |.::.|:...
  Rat   214 KGRSASQKEGSDGDNEDDDDEGSGSEEDENDEG-----NDEDHSSPASEA-----GGKKKKSKVL 268

  Fly   524 PRKTPARRK--KDSITTSPAVSS 544
            .|.:....:  .||:|.|.:.|:
  Rat   269 SRNSADDEELTNDSLTLSQSKSN 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224
Phf14	XP_006236166.1	PHD1_PHF14	313..369	CDD:277036
		ePHD_PHF14	377..490	CDD:277144
		PHD2_PHF14	719..768	CDD:277037
		PHD3_PHF14	862..920	CDD:277038
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900