DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4B and mllt10

DIOPT Version :9

Sequence 1:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_017209395.2	Gene:	mllt10 / 492342	ZFINID:	ZDB-GENE-041114-176	Length:	1162	Species:	Danio rerio

Alignment Length:	311	Identity:	67/311 - (21%)
Similarity:	108/311 - (34%)	Gaps:	88/311 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   448 DDGTEDDDEEEDFKRRKQKRR----------------------------YDADYDDDWLASKRKT 484
            |..|...|:..|.:::|.|.|                            |:.......::|...|
Zfish   284 DSSTHSLDKHHDKEKKKHKERDRHKPKHKKPLELSPSLVPALMVTPEKSYNNSSSGGSVSSISST 348

  Fly   485 NSR-NNRGRSPRTKDDRSISPASSTSSTSRGARRGKASGTPRKTPARRKKDSITTSPAVSS---A 545
            ..| ::.|......:.:.:.|.||:||...|:..||:|      .::.||.|.:||.:..|   .
Zfish   349 QKRLDDSGARFTNANFQEVPPHSSSSSKDGGSSDGKSS------DSKSKKSSHSTSSSSGSRGRK 407

  Fly   546 ATAVKTPTSAVVAGTTSIATTTTPPAD-----GGGDAKKERQSLQFMQQSRKF-EGKIPKLSQTS 604
            :.|.|.....|...|:|.|.::|.|..     |...:.|...|...:|.:..| ....|.|....
Zfish   408 SVAGKPHGPVVTTATSSTAPSSTSPFQQGHLLGSNSSSKSATSGSVVQPTSDFLSFSDPSLRAGD 472

  Fly   605 AAT----------GGATAAAEASTSKSSQGQQQQIVYVNMLPAANTLNGIPQQQQQQQYASTDGN 659
            :.|          |||.:.|..|                 :.|.||.:.||..|     :|:..:
Zfish   473 SYTPPSFGRCHMKGGAESGASES-----------------MVALNTFSMIPLSQ-----SSSSSS 515

  Fly   660 VYQLQNEILCDANGHAVTAATASYQTTASSPQQQQQQQQQQQNVATSVAAT 710
            ....:|   |...|...:.|:|||         ::.|.....:.|||.::|
Zfish   516 SKHYEN---CHTTGELGSLASASY---------KRPQPSSSSSSATSSSST 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224
mllt10	XP_017209395.2	PHD_AF10_AF17	50..97	CDD:277049
mllt10	XP_017209395.2	ePHD_AF10	148..273	CDD:277178
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900