DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4B and rno

DIOPT Version :9

Sequence 1:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	NP_001246528.1	Gene:	rno / 38027	FlyBaseID:	FBgn0035106	Length:	3241	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	71/365 - (19%)
Similarity:	123/365 - (33%)	Gaps:	119/365 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   357 LDVLLCDKKMKKQCNPTKAKSFKERNPDLDLDEI---QQNPNVPD----------------DVKA 402
            ||.:..:|:..||         :::.|.:||:.:   ...|.:.|                |:|.
  Fly   671 LDEMRLEKQQTKQ---------EQQQPVMDLNAVIYANDGPTLYDRFYSSVGGQTVPAQYQDLKY 726

  Fly   403 MLKESVLTLDTGDLATDEADFPNEDAMSLQSPANLKTKQELLEYIDDGTEDDDEEEDFKRRKQKR 467
            :|::.:..|.:|......|.         |||                          .:|||
  Fly   727 ILEQLMGKLQSGKQGRGRAS---------QSP--------------------------NKRKQ-- 754

  Fly   468 RYDADYDDDWLASKRKTNSRNNRGRSPRTKDDRSISPASSTSSTSRGARRGKASGTPRKTPARRK 532
                       .:|...|.:.|.|    ....|:.||..:.:.:..|....|....|.|.|..|:
  Fly   755 -----------PAKASPNKKLNNG----ILSSRTSSPEKTVAGSKVGTTTSKVRSPPGKNPTGRR 804

  Fly   533 KDSITTSPAVSSAATAVKTPTSAVVAGTTSIATTTTPPADGGGDAKKERQSLQFMQQSRKFEGKI 597
            ...       ||||.|..|...:..  .::|.::||..:..|..:.....|......|....|
  Fly   805 ASK-------SSAAAATSTHNKSQF--HSNIRSSTTSHSSSGTISSGNSSSANGTSSSDSSSG-- 858

  Fly   598 PKLSQTSAATGGATAAAEASTSKSSQGQQQQIVYVNMLPAANTLNGIPQQQQQQQYASTDGNVYQ 662
               |.:.:.:|.::|.:..|..|||.|        :.|...:....:.|:|:|:|         :
  Fly   859 ---SDSGSESGSSSAGSGVSKRKSSSG--------SPLKKQSYARSVEQRQKQRQ---------R 903

  Fly   663 LQNEILCDANGHAVTAATASYQTTASSPQQQQQQQQQQQN 702
            .|||        ||..|:|:|..:.|:......:.::.:|
  Fly   904 RQNE--------AVAGASATYPDSRSASSSSDGEDERCRN 935

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224
rno	NP_001246528.1	COG5141	250..>664	CDD:227470
		EPL1	<250..288	CDD:287484
		PHD_JADE	314..359	CDD:277048
		ePHD_RNO	367..480	CDD:277177
		TFIIA	2138..>2295	CDD:281188
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900