DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4B and Brd1

DIOPT Version :9

Sequence 1:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_006242256.1	Gene:	Brd1 / 315210	RGDID:	1311855	Length:	1189	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	54/272 - (19%)
Similarity:	85/272 - (31%)	Gaps:	68/272 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 FQSDRYDLWMEGRDVGRHPEDP--------PNAVLSAAPLPP-----HLDVLLCDKKMKKQCNPT 373
            |.::.:....:...|..||.:|        |.|..||...|.     ...||.|  |.|....|.
  Rat   833 FDNESHSTCTQSALVSGHPPEPTLASSGDVPAAAASAVAEPSSDVNRRTSVLFC--KSKSVSPPK 895

  Fly   374 KAKSFKERNPDLDLDEIQQNPNVPD-DVKAMLKESVLTLDTGDLATDEADFPNEDAMSLQSPANL 437
            .||:            .:..|..|. ..|..|...:..|:|                 |..|...
  Rat   896 SAKN------------TETQPTSPQLGTKTFLSVVLPRLET-----------------LLQPRKR 931

  Fly   438 KTKQELLEYIDDGTEDDDEEEDFKRRKQKRRYDADYDDDW--LASKRKTNSRNNRGRSPRTK--D 498
            ..          .|..|.|.|:   ....:|.|....:.:  ..|:::..|...|..:||.:  .
  Rat   932 SR----------STCGDSEVEE---ESPGKRLDTGLTNGFGGTRSEQEPGSGPGRKAAPRRRCAS 983

  Fly   499 DRSI----SPASSTSSTSRGARRGKASGTPRKTPARRKK--DSITTSPAVSSAATAVKTPTSAVV 557
            :.||    ||...:|.::....|||.:...|.|...|.:  ..|.......:|..|.:...:::.
  Rat   984 ESSICSSNSPLCDSSFSTPKCGRGKPALVRRHTLEDRSELISCIENGNYAKAARIAAEVGQNSMW 1048

  Fly   558 AGTTSIATTTTP 569
            ..|.:.|:...|
  Rat  1049 ISTDAAASVLEP 1060

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224
Brd1	XP_006242256.1	EPL1	47..196	CDD:287484
		PHD_BRPF2	214..267	CDD:277147
		ePHD_BRPF2	271..388	CDD:277172
		Bromo_brd1_like	566..663	CDD:99944
		BR140_related	1058..1173	CDD:99900	1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900