Protein Alignment Kdm4B and jmj3

DIOPT Version :9

• Sequence 1: NP_001260942.1
• Gene: Kdm4B / 318918
• FlyBaseID: FBgn0053182
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_595639.1
• Gene: jmj3 / 2540780
• PomBaseID: SPBC83.07
• Length: 752
• Species: Schizosaccharomyces pombe
• Alignment Length: 709
• Identity: 140/709 - (19%)
• Similarity: 245/709 - (34%)
• Gaps: 196/709 - (27%)

  Fly     9 IKVFRPTWEEFKDFPKYVAYMESQGAHKAGLAKVVPPPE----WVPRRSGYADLDAL---NVTIP 66
            |.|..|...||.|...::..:|..| .|.|..|||.|..    |        :.|.:   :|.:.
pombe    34 IPVVEPKISEFVDMESFIRRVERLG-KKYGAIKVVRPSSVLNPW--------NEDTMKPSDVKMD 89

  Fly    67 APICQVVTGKQGYYQ-QINIQ------KKPLTVK---QFSELASTERYATPKHFDFEDLERK--- 118
            ..:.::|..|..|:: |.:|.      |||..:.   :|...|.:..       |||:...|
pombe    90 LWLERMVRRKGEYFEIQSDIDHGSAGPKKPTDMNVDDRFPSNAGSSN-------DFENNVAKAIA 147

  Fly   119 -YWKNITYVAPIYGAD--------VSGSITDTDQDSWNINRLGTILDYVNKDYNIQIDGVNTAYL 174
             ||:::|:.:..||..        ...||:...:|..:: |..|:::          ...|..:|
pombe   148 YYWRSLTHDSLWYGYTNRPSIPFYFIPSISAAQKDRVHL-RSNTLIN----------TWPNVGHL 201

  Fly   175 YFGMWKTTFAWHTEDMDLYSINYLHFGAPKTWYVVPPECGRKLEKVANQYFPASYKNCNAYLRHK 239
            :.|.||||..|..|..:|:::.....|:...|||:|.......:|:|.:.....:..|:.:|.|:
pombe   202 FAGKWKTTLPWRVESPELHAVQVHLGGSSLQWYVIPSAHSESFKKLAGKLAQDEHWRCSDFLLHQ 266

  Fly   240 MTLISPQILKQHDVPVSKITQEAGEIMITFPFGYHAGF-------------------NHGFN--- 282
            ..|..|..|.|:.:.......:..|::||||..:|:.|                   |:.|:
pombe   267 NILFPPSTLVQNGIVTYSTVLKQDELLITFPGTHHSAFCLGDAVLRRFVFRSPRSASNYEFSNLR 331

  Fly   283 ---CAESTNFAMERWIEYGKRAVQCTCSNDMVKISMDTFVKRF------QSDRYDLW-------- 330
               .:||...:...|....|  .|..||        ..|:..|      :|:.:|..
pombe   332 RLMVSESLYSSKSLWPHSHK--PQRACS--------QKFLDEFYLHDLPESNIHDSGNFHPIHSS 386

  Fly   331 MEGRDVGRHPEDPPNAVLSAAPLPPHLDVLLCDKKMKKQCNPTKAKSFKERNPDLDLDEIQQNPN 395
            ::.....:...|.||::...:||..:     .:....:..|.|.... ||.: .|.:.|.::|.:
pombe   387 VDNNSFSQRDFDSPNSINPPSPLMSN-----HESASTEHFNSTTTTE-KELS-SLHVGEERKNRS 444

  Fly   396 VP-----------DDVKAMLKESVLTLDTGDLATDEADFPNED---------------AMSLQSP 434
            :|           :.:|...:|:          .|..:|.:.|               .:.|..|
pombe   445 LPLSLIWNSKAREEYIKKQKEEN----------GDNIEFSHFDPLYTRPSSHPLHPPPILGLPVP 499

  Fly   435 ANLKTKQELLEYIDDGTEDDDEEEDFKRRKQKR-----RYDADYDDDWLASKRKTNSRNNRGRSP 494
            |.....:..|..|   .||...|.......:|.     .|:........|.:|:::..|...::|
pombe   500 AQFARGELFLGRI---LEDRVSEHMLLLECEKSDVVEVPYECILTSSSAAGRRESSYYNPALKAP 561

  Fly   495 RTKDDRSI----SPASSTSSTSRGARRGKASGTPRKTPARRKKDSITTSPAVSSAATAVKT---- 551
            ....|..:    :..|...|..|..       .|:..|.:    .|..:|.:|...|::||
pombe   562 NIVYDDGVPINWNEYSELPSLDRFV-------LPKLLPGK----PIEFTPPISVEPTSIKTIAAE 615

  Fly   552 ----PTSAVVAGTT-----------------SIATTTTPPADGGGDAKKERQSLQFMQQ 589
                |||:|....|                 |:...:.|.....|....||.|:..:::
pombe   616 ESSEPTSSVDVAPTPVEDVNVNLESISNTNESVVDLSDPLVSKNGFEDVERSSVADLEE 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526	11/32 (34%)
		JmjC	173..289	CDD:202224	34/140 (24%)
jmj3	NP_595639.1	JmjN	33..74	CDD:128818	14/40 (35%)
		JmjC	200..316	CDD:202224	30/115 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10694
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910