DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33181 and slc41a2a

DIOPT Version :9

Sequence 1:	NP_001096908.1	Gene:	CG33181 / 318916	FlyBaseID:	FBgn0053181	Length:	696	Species:	Drosophila melanogaster
Sequence 2:	XP_693342.4	Gene:	slc41a2a / 564932	ZFINID:	ZDB-GENE-130530-781	Length:	494	Species:	Danio rerio

Alignment Length:	425	Identity:	181/425 - (42%)
Similarity:	278/425 - (65%)	Gaps:	4/425 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 AGINGSSEEKLALNRPGIKQEKWTTILLQVSIPFFLAGIGTIGAGIVLGRVEKWYVFKNVSELFI 317
            |.:|.|.:|  ..|...:..|....::||:..||.|||.||:.||::|..|:.|.||:||:|:||
Zfish    65 ATVNISQDE--PHNIQEMPSESIRAMVLQILFPFLLAGFGTVLAGMLLDVVQHWDVFRNVTEIFI 127

  Fly   318 LVPALLGLKGNLDMCLASRLSTQVNLGNMTSRQGVIRMIVGNIALVQVQATVASFLVAMFAVSVG 382
            |||.||||||||:|.|||||||.||:|.|...:....:|.||:||.||||||..||.|:.|..:.
Zfish   128 LVPPLLGLKGNLEMTLASRLSTAVNVGRMNCSREKWNLIKGNLALKQVQATVLGFLAALVASFLE 192

  Fly   383 AAMTGDFYFENMMLLTASAMFTATSSCFVLDFVLVAVILFSQKYRLNPDNLATPLAASIGDVVSI 447
            ..:..:....::.||...::.||.::..:...::|.||:.|:|..:||||:|||:|||.||::::
Zfish   193 WILKAELITNHVALLCGCSVVTAFTASLLQGILMVGVIIGSKKVGINPDNIATPIAASFGDLITL 257

  Fly   448 SLLSFIASLLYDHIKTHLWITFIVVTCYLVLLPMWVMIVLRNEYTRPVLKSGWVPVLSALCISGL 512
            .||:.|:..||..::.:.:||::|...:|.|.||||::...:..::.:|.|||.||::|:.||.|
Zfish   258 GLLAVISQGLYYCMEPYPYITYLVCLFFLCLTPMWVILSFHHPESQKLLFSGWEPVITAMVISSL 322

  Fly   513 GGLVLDAAV--EVFNGFVVFQPIINGIGGNLVSVQASKISTMLHQSSIIGIIPPHTQIFEWPWRA 575
            |||:||..:  ...:|.|::.|:|||:||||||:|||:|:|.||....:|.:|..|:....|.|.
Zfish   323 GGLILDRTITNPKLDGLVLYTPVINGVGGNLVSIQASRIATYLHFQCPLGELPEDTKGCYCPCRY 387

  Fly   576 LFKGVPYAKTARILIAMSIPGNVLFIFAADYINYSTSTVTWVFVLSYLTASLVQVMLLLYIAHII 640
            .....|..::|::|:.:..||:::||:....|..|.|..|.||:..|:.|:..||:||:.||.::
Zfish   388 FCSKGPNGRSAQVLLTLVAPGHLVFIYTIYIIQGSQSPPTAVFIFFYIIAAFTQVLLLMSIADVM 452

  Fly   641 VHAMWKWKIDPDNSAIPYLTALGDLLGSSLLAVAW 675
            ||.:|::..|||:.:||||||||||||::|||:.:
Zfish   453 VHCLWRYGRDPDSFSIPYLTALGDLLGTALLALCF 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33181	NP_001096908.1	MgtE	319..450	CDD:280023	58/130 (45%)
CG33181	NP_001096908.1	MgtE	531..661	CDD:280023	53/129 (41%)
slc41a2a	XP_693342.4	MgtE	129..260	CDD:280023	58/130 (45%)
slc41a2a	XP_693342.4	MgtE	343..483	CDD:280023	61/139 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580348
Domainoid	1	1.000	132	1.000	Domainoid score	I5062
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2101
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1059294at2759
OrthoFinder	1	1.000	-	-		FOG0001493
OrthoInspector	1	1.000	-	-		otm24808
orthoMCL	1	0.900	-	-		OOG6_102999
Panther	1	1.100	-	-	O	PTHR16228
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1062
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.900