Protein Alignment CG33181 and SLC41A3

DIOPT Version :10

• Sequence 1: NP_001096908.1
• Gene: CG33181 / 318916
• FlyBaseID: FBgn0053181
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_005247616.1
• Gene: SLC41A3 / 54946
• HGNCID: 31046
• Length: 522
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 171/462 - (37%)
• Similarity: 263/462 - (56%)
• Gaps: 29/462 - (6%)

  Fly   234 GGNGGIG-------SGALVAADASSIAGINGSSEEKLALNRPGIKQEKWTTILLQVSIPFFLAGI 291
            |..|.:|       .|..||::..::......|.....|.....::..| :|.|||::||..||:
Human    15 GKPGELGLPHPLSTGGLPVASEDGALRAPESQSVTPKPLETEPSRETTW-SIGLQVTVPFMFAGL 78

  Fly   292 GTIGAGIVLGRVEKWYVFKNVSELFILVPALLGLKGNLDMCLASRLST---------------QV 341
            |...||::|...:.|.||..|.:|..|||.|:||||||:|.|||||||               |.
Human    79 GLSWAGMLLDYFQHWPVFVEVKDLLTLVPPLVGLKGNLEMTLASRLSTAVSGHLDIRGGHNVRQA 143

  Fly   342 NLGNMTSRQGVIRMIVGNIALVQVQATVASFLVAMFAVSVGAAMTGDFYFENMMLLTASAMFTAT 406
            |.|.:...|...|:|..|:||:||||||...|.|:.|:.:|.....:.....:.||.||::.||.
Human   144 NTGQIDDPQEQHRVISSNLALIQVQATVVGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAF 208

  Fly   407 SSCFVLDFVLVAVILFSQKYRLNPDNLATPLAASIGDVVSISLLSFIASLLYDHIKTHLWITFIV 471
            .:.|.|..::|.:::.::|..:||||:|||:|||:||::::|:|:.::|..|.| |...::|.:|
Human   209 LAAFALGVLMVCIVIGARKLGVNPDNIATPIAASLGDLITLSILALVSSFFYRH-KDSRYLTPLV 272

  Fly   472 VTCYLVLLPMWVMIVLRNEYTRPVLKSGWVPVLSALCISGLGGLVLDAAV--EVFNGFVVFQPII 534
            ...:..|.|:||:|..::.....:||.||.|::.|:.||..|||:|...|  :.:.|..:|.|:|
Human   273 CLSFAALTPVWVLIAKQSPPIVKILKFGWFPIILAMVISSFGGLILSKTVSKQQYKGMAIFTPVI 337

  Fly   535 NGIGGNLVSVQASKISTMLHQSSIIGIIPPHTQIFEW--PWRALFKGVPYAKTARILIAMSIPGN 597
            .|:|||||::|.|:|||.||..|..|::|...:.| |  |..........:.:||:|:.:.:||:
Human   338 CGVGGNLVAIQTSRISTYLHMWSAPGVLPLQMKKF-WPNPCSTFCTSEINSMSARVLLLLVVPGH 401

  Fly   598 VLFIFAADYINYSTSTVTWVFVLSYLTASLVQVMLLLYIAHIIVHAMWKWKIDPDNSAIPYLTAL 662
            ::|.:....:...:...:..||:.||.|.|:||.:|||:|.::|...|...:||||..|||||.|
Human   402 LIFFYIIYLVEGQSVINSQTFVVLYLLAGLIQVTILLYLAEVMVRLTWHQALDPDNHCIPYLTGL 466

  Fly   663 GDLLGSS 669
            |||||||
Human   467 GDLLGSS 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33181	NP_001096908.1	MgtE2	278..457	CDD:441429	79/193 (41%)
		MgtE	531..661	CDD:460317	49/131 (37%)
SLC41A3	XP_005247616.1	MgtE	106..255	CDD:460317	60/148 (41%)
		MgtE	334..471	CDD:460317	54/137 (39%)