DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33181 and slc41a1

DIOPT Version :9

Sequence 1:	NP_001096908.1	Gene:	CG33181 / 318916	FlyBaseID:	FBgn0053181	Length:	696	Species:	Drosophila melanogaster
Sequence 2:	XP_031752731.1	Gene:	slc41a1 / 100494432	XenbaseID:	XB-GENE-488920	Length:	528	Species:	Xenopus tropicalis

Alignment Length:	459	Identity:	208/459 - (45%)
Similarity:	289/459 - (62%)	Gaps:	43/459 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 NGS----SEEKLALNRPGIK---QEKWTTILLQVSIPFFLAGIGTIGAGIVLGRVEKWYVFKNVS 313
            |||    |::..|...|.:.   :|...:|.|||..||.|||.||:.||:||..|:.|.||..|:
Frog    65 NGSQSTESDDPNADACPEVSIPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFTEVT 129

  Fly   314 ELFILVPALLGLKGNLDMCLASRLSTQVNLGNMTSRQGVIRMIVGNIALVQVQATVASFLVAMFA 378
            |:||||||||||||||:|.|||||||.||:|.|.:.:....||.|||||:||||||..||.:|.|
Frog   130 EVFILVPALLGLKGNLEMTLASRLSTAVNIGQMETSKEKWAMITGNIALIQVQATVVGFLASMAA 194

  Fly   379 VSVGAAMTGDFYFENMMLLTASAMFTATSSCFVL-------------------DFVLVAVILFSQ 424
            |..|..:.|.|..::.:||.||::.||..:..||                   ..|::.||:.|:
Frog   195 VIFGWILDGHFLMDHAVLLCASSVSTAFIASMVLGEKKSFPSSCKHIKRMTGQGLVMIGVIIGSK 259

  Fly   425 KYRLNPDNLATPLAASIGDVVSISLLSFIASLLYDHIKTHLWITFIVVTCYLVLLPMWVMIVLRN 489
            |..:||||:|||:|||:||:|:::|||.|:..||..||.::::..:|...:|.|||:|.:|..||
Frog   260 KLGINPDNVATPIAASLGDLVTLALLSGISCGLYKEIKNNVYVNPVVCILFLALLPIWFVIARRN 324

  Fly   490 EYTRPVLKSGWVPVLSALCISGLGGLVLDAAVE--VFNGFVVFQPIINGIGGNLVSVQASKISTM 552
            ..||.||.|||.||:.|:.||.:|||:||..|.  .|.|..||.|:|||:|||||:||||:|||.
Frog   325 PATREVLSSGWEPVIIAMAISSVGGLILDKTVSNPNFAGMAVFTPVINGVGGNLVAVQASRISTY 389

  Fly   553 LHQSSIIGIIPP--HTQIF----EWPWRALFKGVPYAKTARILIAMSIPGNVLFIFAADYINYST 611
            ||.:.     ||  .|::.    ..|.|..|.....:::||:|....:||:::|::....:....
Frog   390 LHMTG-----PPGEETELIPRKCPSPCRTFFSSDMNSRSARVLFLFVVPGHLIFLYTISSMQGGH 449

  Fly   612 STVTWVFVLSYLTASLVQVMLLLYIAHIIVHAMWKWKIDPDNSAIPYLTALGDLLGSSLLA---- 672
            :|:|.:|::.|:.|:|:||::|||||..:||.||...:||||.:||||||||||||:.|||
Frog   450 TTLTLIFMVFYMMAALLQVLVLLYIADWMVHWMWGRGMDPDNFSIPYLTALGDLLGTGLLALSFH 514

  Fly   673 VAWL 676
            :.||
Frog   515 ILWL 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33181	NP_001096908.1	MgtE	319..450	CDD:280023	70/149 (47%)
CG33181	NP_001096908.1	MgtE	531..661	CDD:280023	55/135 (41%)
slc41a1	XP_031752731.1	MgtE	135..285	CDD:396364	70/149 (47%)
slc41a1	XP_031752731.1	MgtE	368..498	CDD:396364	54/134 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	136	1.000	Domainoid score	I4886
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2101
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1059294at2759
OrthoFinder	1	1.000	-	-		FOG0001493
OrthoInspector	1	1.000	-	-		otm49067
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1062
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060