Protein Alignment mthl15 and adgrl4

DIOPT Version :10

• Sequence 1: NP_723538.3
• Gene: mthl15 / 318914
• FlyBaseID: FBgn0051720
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_998532.3
• Gene: adgrl4 / 406676
• ZFINID: ZDB-GENE-040426-2689
• Length: 738
• Species: Danio rerio
• Alignment Length: 300
• Identity: 71/300 - (23%)
• Similarity: 119/300 - (39%)
• Gaps: 76/300 - (25%)

  Fly   388 IGLLIS------CCFYALTLIVYISIAKLRNLPGKILICLVSSLFAAYLGIALGQLRPTSNDDIC 446
            :|::||      |.|   |...:..|...|....|.|.|   |||.|.....:| :..:::...|
Zfish   481 LGMVISLICLSMCIF---TFWFFRDIQNTRTTIHKNLCC---SLFMAQFIFLIG-INKSAHKWFC 538

  Fly   447 FLSGFFVYFCLMAAFSWMNITSFDIWKTFGSTKLKSCEKSDLRRQFIWYSCYGWGLPTLLTGITI 511
            .|....:::..:|||:||.|....::......   ...|..|.|.|.   .:|:|.|.::..|:.
Zfish   539 SLIAGLLHYFFLAAFAWMCIEGIHLYLIVVGV---IYNKGFLHRNFY---AFGYGSPAVVVAISA 597

  Fly   512 A-----FTKSDILPDAVRPNFGHGRCWF-TYDSFGSASLLFFSGPVGILFIINLVLFVLTMKYCN 570
            .     :..|.:             ||. |.::|    :..|.||..::.::||:.|.:.
Zfish   598 TLGYKYYGTSSV-------------CWLSTENNF----IWSFIGPAILIILVNLLAFAVI----- 640

  Fly   571 KVKNEIYKMQSLNS-DKPVLKRRFFQDKTRFVMNTKLC--------FVMGITWLLEIVSILFYDH 626
                 |||:....: .||.:..         ..|.:.|        ||:|:||...::.||:...
Zfish   641 -----IYKVYRHTAVKKPEISH---------YENIRSCARGAIALLFVLGVTWAFGVMYILYETT 691

  Fly   627 KKTFFWTISDSFNVLLGIFVFI-IFVFKRRIYNEI--MFK 663
            ...:.:|.:   ||..|:|:|| :.|..|||..|.  :||
Zfish   692 LTAYLFTFA---NVFQGMFIFIFLCVLSRRIQEEYYRLFK 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl15	NP_723538.3	Mth_Ecto	<247..355	CDD:448329
		7tmB3_Methuselah-like	379..665	CDD:410632	70/299 (23%)
		TM helix 1	381..406	CDD:410632	6/23 (26%)
		TM helix 2	415..437	CDD:410632	8/21 (38%)
		TM helix 3	447..474	CDD:410632	7/26 (27%)
		TM helix 4	492..512	CDD:410632	5/19 (26%)
		TM helix 5	537..569	CDD:410632	7/31 (23%)
		TM helix 6	595..622	CDD:410632	7/34 (21%)
		TM helix 7	627..654	CDD:410632	8/27 (30%)
adgrl4	NP_998532.3	None