DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl15 and LOC108181087

DIOPT Version :9

Sequence 1:	NP_723538.3	Gene:	mthl15 / 318914	FlyBaseID:	FBgn0051720	Length:	718	Species:	Drosophila melanogaster
Sequence 2:	XP_021329169.1	Gene:	LOC108181087 / 108181087	-ID:	-	Length:	166	Species:	Danio rerio

Alignment Length:	204	Identity:	47/204 - (23%)
Similarity:	77/204 - (37%)	Gaps:	49/204 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   453 VYFCLMAAFSWMNITSFDIWKTFGSTKLKSCEKSDLRRQFIWYSCYGWGLPTLLTGITIAFTKSD 517
            ::...|||||||.:....:|....|..|..      .|...:|...|||||.|:..||:|.....
Zfish     1 MHLFFMAAFSWMLVEGLLLWSKVVSVNLSE------DRHMKYYYLIGWGLPVLIVTITLASASGK 59

  Fly   518 ILPDAVRPNFGHGRCWFTYDSFGSASLLFFSGPVGILFIINLVLF--VLTMKYCNKVKNEIYKMQ 580
            ...|        |.||.   |..:..:..|:|||..:.::|:::.  |:.:......:..:  |.
Zfish    60 YTAD--------GHCWL---SVQNGVIWGFAGPVIFIIMVNIMILTRVVVITIATAKRRSL--MM 111

  Fly   581 SLNSDKPVLKRRFFQDKTRFVMNTKLCF--VMGITWLLEIVSILFYDHKKTFFWTISDSFNVLLG 643
            :||:.    ......::.|..:...|..  ::|:|||.                      .||:.
Zfish   112 ALNNS----PEEQISEQIRAAVKAVLVLLPILGLTWLC----------------------GVLVP 150

  Fly   644 IFVFIIFVF 652
            ..|.|.:||
Zfish   151 FSVVIAYVF 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl15	NP_723538.3	Mth_Ecto	<247..355	CDD:299804
mthl15	NP_723538.3	7tm_4	385..646	CDD:304433	43/196 (22%)
LOC108181087	XP_021329169.1	7tm_GPCRs	<1..166	CDD:333717	47/204 (23%)
		TM helix 4	36..52	CDD:320095	7/15 (47%)
		TM helix 5	71..94	CDD:320095	5/22 (23%)
		TM helix 6	126..151	CDD:320095	8/46 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1153592at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010