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Protein Alignment Ir31a and Grik2

DIOPT Version :9

Sequence 1:	NP_001260346.1	Gene:	Ir31a / 318912	FlyBaseID:	FBgn0051718	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_062182.1	Gene:	Grik2 / 54257	RGDID:	2733	Length:	908	Species:	Rattus norvegicus

Alignment Length:	754	Identity:	142/754 - (18%)
Similarity:	255/754 - (33%)	Gaps:	170/754 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KSLVKTKQAIVFSCLFKDFKEISLALMRINQF-----VSVV-----NLNQSYSLTSILTRENYAR 87
            |..|...:...:..|:.||..:|.|::.:.||     |:||     .|.:...|....:|.|...
  Rat   135 KHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRL 199

  Fly    88 TSVMVNARCSGSSELLFEASENRYFN------------------------KTYQWFLWGVDLEVQ 128
            ....:.|....:..||.|....:.|:                        :.|.:....:||...
  Rat   200 KIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFAL 264

  Fly   129 SLFPL---NLNYVG------PNAQITYVNE----------------------TADGYAYWD-IHS 161
            .:.|.   .:|..|      .|.|::.:.|                      |.|....:| :|.
  Rat   265 DVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHV 329

  Fly   162 KGRHLK-------SNLEIN----------------------LIATLINDTLNIARDIFHLQSIDF 197
            ....::       |:|:.|                      |...:..:..|..|..|.|..|..
  Rat   330 VSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISL 394

  Fly   198 RGQ----------FNGLTL------RGASVIDKEDIISNEQ--IESILSRP-----TKDA---GV 236
            :.:          .:||.:      :.|::.|.   :||..  :.:||..|     ..|.   |.
  Rat   395 KEEGLEKIGTWDPASGLNMTESQKGKPANITDS---LSNRSLIVTTILEEPYVLFKKSDKPLYGN 456

  Fly   237 AAFIKYHYELLGLLRERFNFTVNFRNSRGWAGRLG-----NTTFRLGLLGIVMRNEADIAASGAF 296
            ..|..|..:||..|.....||...|....  |:.|     |..:. |::..::.::||:|.:...
  Rat   457 DRFEGYCIDLLRELSTILGFTYEIRLVED--GKYGAQDDVNGQWN-GMVRELIDHKADLAVAPLA 518

  Fly   297 NRINRFAEFDTIHQSWKFETAFLYRYTSDLDTHGKSGNFLSPFSDRVWLFCLLT-LGAFSIIWVL 360
            ....|....|..........:.|||..:  .|:....:||:|.|..:|::.||. ||...:::|:
  Rat   519 ITYVREKVIDFSKPFMTLGISILYRKPN--GTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVI 581

  Fly   361 FEIIDYKILRIRVNSQKLEH-LNQKSSVICIKTTCIERILQTFGACCQQGLDPNPVDRSVRFLVM 424
            .....|:...        .| .|..|.|:....|.:.......||..:||.:..|...|.|.:..
  Rat   582 ARFSPYEWYN--------PHPCNPDSDVVENNFTLLNSFWFGVGALMRQGSELMPKALSTRIVGG 638

  Fly   425 TLFLFSLVMYNYYTSSVVGGLLSSSDQGPSTVDEITASPLKISF---EDIGYYKVLFRESQNRSI 486
            ..:.|:|::.:.||:::...|.....:.|....:..|...||.:   || |.....|::|:
  Rat   639 IWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVED-GATMTFFKKSK---- 698

  Fly   487 TRLIEKKLSSSRSLNELPIFSHIEDAVPYLKAGGFAFHCEVVDAYPVISEYFDANEICDLREVSG 551
            ....:|..:...|..:..:....|:.:..:....:||..|..      :..|.....|:|.::.|
  Rat   699 ISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMEST------TIEFVTQRNCNLTQIGG 757

  Fly   552 LMEVEILNWILHKNSQYTEIFKTAMCNAQEKG----FVERILRRRQIKKPACQSLYTVYPVSLSG 612
            |::.:.........|.|.:....|:...||:|    ..|:..|.....:...:....:...::.|
  Rat   758 LIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGG 822

  Fly   613 VLPGFVILICGFGASLLLLCLEKVY-----AHFGPRKFC 646
            :   |::|..|...|:.:...|.:|     |....|.||
  Rat   823 I---FIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFC 858

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.