Protein Alignment Ir31a and gria4b

DIOPT Version :9

• Sequence 1: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 725
• Identity: 148/725 - (20%)
• Similarity: 261/725 - (36%)
• Gaps: 188/725 - (25%)

  Fly     8 FILILAAGEGEIIPSMEESVVTNFVKSLVKTKQAIVFSCLFKDFKEISLALMRINQFV------- 65
            |::.|   |.|.:.:|.|.:|:  |...||....|:.:..|||        :.:.:|:
Zfish   209 FVIDL---EAERLNNMLEQIVS--VGKHVKGYHYIMANLGFKD--------INLERFMHGGANVT 260

  Fly    66 ----------SVVNLNQSYS---------------LTSILTRE----------NYARTSVMVNAR 95
                      .|:.|.|.::               .||.||.:          |..|..|.::.|
Zfish   261 GFQLVDFSNPMVIKLMQRWNKLDQREYPGSDAPPKYTSALTYDGVMVMAEAFRNLRRQKVDISRR 325

  Fly    96 CSGSSELLFEASENRYFNKTYQWFLW--GVDLEVQSLFPLNLNYVGPNAQITY----VNETADGY 154
            ......|...|:.            |  |:|:| ::|..::|..:..|.|..:    ||.|.|.:
Zfish   326 GIAGDCLANPAAP------------WNQGIDME-RTLKQVHLQGLTGNVQFDHYGRRVNYTMDVF 377

  Fly   155 ----------AYWDIHSKGRHLKSNLEINLIAT-----LINDTLNIARDIFHLQSIDFRGQFNGL 204
                      .||:...|           |:.|     |.|:|..:......:.:|
Zfish   378 ELKSNGPRRIGYWNDADK-----------LVLTQDHALLPNETSGMENRTVIVTTI--------- 422

  Fly   205 TLRGASVIDK---EDIISNEQIESILSRPTKDAGVAAFIKYHYELLGLLRERFNFTVNFRNSRGW 266
             :.|..|:.|   |....|||.|...      ..:|:.|..|   :|     |.:.::......:
Zfish   423 -MEGPYVMLKKNWEMYEGNEQYEGYC------VDLASEIAKH---IG-----FKYKISIVPDGKY 472

  Fly   267 AGRLGNTTFRLGLLGIVMRNEADIAASGAFNRINRFAEFDTIHQSWKFETAFLYRYTSDL---DT 328
            ..|...|....|::|.::..:|:||.:.....:.|....|       |...|:....|.:   ..
Zfish   473 GARDPETKIWNGMVGELVYGKAEIAVAPLTITLVREEVID-------FSKPFMSLGISIMIKKPQ 530

  Fly   329 HGKSG--NFLSPFSDRVWLFCLL--TLGAFSIIWVLFEIIDYKILRIRVNSQKLEH------LNQ 383
            ..|.|  :||.|.:..:|: |::  .:|...:::::.....|:     .::::.|.      .:|
Zfish   531 KSKPGVFSFLDPLAYEIWM-CIVFAYIGVSVVLFLVSRFSPYE-----WHTEEPEEGTDGLPSDQ 589

  Fly   384 KSSVICIKTTCIERILQTFGACCQQGLDPNPVDRSVRFLVMTLFLFSLVMYNYYTSSVVGGLLSS 448
            ..:...|    ...:..:.||..|||.|.:|...|.|.:....:.|:|::.:.||:::...|...
Zfish   590 PPNEFGI----FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVE 650

  Fly   449 SDQGPSTVDEITASPLKISFE--DIGYYKVLFRESQNRSITRLIEKKLSSSRSLNELPIFSHIED 511
            ....|....|..|....|::.  |.|..|..||    ||...:.||..|..:|...........:
Zfish   651 RMVSPIESAEDLAKQTDIAYGTLDSGSTKEFFR----RSKIAVYEKMWSYMKSAEPTVFTKTTAE 711

  Fly   512 AVPYLK--AGGFAFHCEVVDAYPVISEYFDANEICDLREVSGLMEVEILNWILHKNSQYTEIFKT 574
            .|..::  .|.:||..|     ..::||.:..:.||..:|.|.::.:.......|.||.......
Zfish   712 GVARVRKSKGKYAFLLE-----STMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSQLRSAVNL 771

  Fly   575 AMCNAQEKGFVERILRRRQIKKPAC------------QSLYTVYPVSLSGVLPGFVILICGFGAS 627
            |:....|:|.::::..:....|..|            |:|      |||.|...|.||:.|.|.:
Zfish   772 AVLKLNEQGLLDKLKNKWWYDKGECGSGGGGEKDKSSQAL------SLSNVAGVFYILVGGLGLA 830

  Fly   628 LLLLCLEKVY 637
            :|:..:|..|
Zfish   831 MLVALIEFCY 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir31a	NP_001260346.1	Lig_chan	401..624	CDD:278489	57/238 (24%)
gria4b	NP_997917.2	Periplasmic_Binding_Protein_Type_1	28..398	CDD:324556	44/225 (20%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	84/428 (20%)
		Lig_chan	546..827	CDD:306551	64/305 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910