Protein Alignment Ir31a and GRIN2C

DIOPT Version :9

• Sequence 1: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 598
• Identity: 109/598 - (18%)
• Similarity: 180/598 - (30%)
• Gaps: 233/598 - (38%)

  Fly   154 YAYWDIHS-------KGRHLKSNLEINLIATL------------------INDTLNIARDIFHLQ 193
            |..|..:|       ..|||       .:|||                  :.:|:...|...|..
Human   459 YPVWPRYSASLQPVVDSRHL-------TVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTF 516

  Fly   194 SIDFRGQFNGLTLRGASVIDKEDIISNEQIESILSRPTKDAGVAAFIKYHYELLGLLRERFNFTV 258
            |......:..|..:|..:    ||:..               :|..:|:.|:|..:...:..
Human   517 SSGDVAPYTKLCCKGFCI----DILKK---------------LARVVKFSYDLYLVTNGKHG--- 559

  Fly   259 NFRNSRG-WAGRLGNTTFRLGLLGIVMRNEADIAASGAFNRINRFAEFDTIHQSWKF-ETAFLYR 321
              :..|| |.|.:|...::          .||:|....  .||. ...:.:..|..| ||.....
Human   560 --KRVRGVWNGMIGEVYYK----------RADMAIGSL--TINE-ERSEIVDFSVPFVETGISVM 609

  Fly   322 YTSDLDTHGKSGNFLSPFSDRVW----LFCL---------------------LTLG------AFS 355
            ......|...|. ||.|:|..||    :.||                     ||.|      ||:
Human   610 VARSNGTVSPSA-FLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTRGKKSGGPAFT 673

  Fly   356 I---IWVLFEIIDYKILRIRVNSQKLEHLNQKSSVICIKTTCIERILQTFGACCQQGLDPNPVDR 417
            |   :|:|:.::..       ||..:|                                 ||...
Human   674 IGKSVWLLWALVFN-------NSVPIE---------------------------------NPRGT 698

  Fly   418 SVRFLVMTLFLFSLVMYNYYTSSVVGGLLSSSDQGPSTVDEITASPLKISFEDIG---------- 472
            :.:.:|:....|:::....||:::...::  .:|...||..: :....:..|:.|
Human   699 TSKIMVLVWAFFAVIFLASYTANLAAFMI--QEQYIDTVSGL-SDKKSLHLENTGVAWTAFKTFC 760

  Fly   473 ----------YYKVLFRESQNRSITRLIEKKLSSSRSLN-ELPIFSH--IEDAVPYLKAGGFAFH 524
                      |....|....|.|..|.|.   |:.|.:: .:..|:.  :|||:..||.|.
Human   761 SDYFQRPQDQYPPFRFGTVPNGSTERNIR---SNYRDMHTHMVKFNQRSVEDALTSLKMGS---- 818

  Fly   525 CEVVDAYPVISE----YFDA---------NEICDLREV-SG-LMEVEILNWILHKNSQYTEIFKT 574
                :|.||..:    .:||         :|.|.|..: || :.........:.|:|.:......
Human   819 ----EAQPVPRKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDL 879

  Fly   575 AMCNAQEKGFVERILRRRQIKKPACQSLYTVYPVSLSGVLPG------------------FVILI 621
            |:......|              ..|.|.||:   |||:...                  |.:|:
Human   880 ALLQFLGDG--------------ETQKLETVW---LSGICQNEKNEVMSSKLDIDNMAGVFYMLL 927

  Fly   622 CGFGASLLLLCLE 634
            ...|.:||:...|
Human   928 VAMGLALLVFAWE 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir31a	NP_001260346.1	Lig_chan	401..624	CDD:278489	49/278 (18%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910