Protein Alignment Ir31a and GRIN2A

DIOPT Version :9

• Sequence 1: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_016878661.1
• Gene: GRIN2A / 2903
• HGNCID: 4585
• Length: 1516
• Species: Homo sapiens
• Alignment Length: 639
• Identity: 116/639 - (18%)
• Similarity: 208/639 - (32%)
• Gaps: 206/639 - (32%)

  Fly    19 IIPSMEESVVTNFVKSLVKT-------KQAIVFSCLFKDFK--------EISLALMRINQFVSVV 68
            |.|...|.:  :|||:.|..       :..|.....|:|.|        ..|:.|:..::..:|:
Human   228 IFPGYREFI--SFVKTTVDNSFVGWDMQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVL 290

  Fly    69 NLNQSYSLTSILTRENYARTSVMVNARCSGSSELLFEASENRYFNKTYQWFLWGVDLE------- 126
            .|:::.||.  ||..::   ..:|.:..||::||:.:...:...:.:|.  .|...||
Human   291 ILSEARSLG--LTGYDF---FWIVPSLVSGNTELIPKEFPSGLISVSYD--DWDYSLEARVRDGI 348

  Fly   127 ----------------------------------VQSLFPLNLNYVGPNAQITYVNETADGYAYW 157
                                              :.:|.|..:|.......:::   |.:||
Human   349 GILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHTLHPFMVNVTWDGKDLSF---TEEGY--- 407

  Fly   158 DIHSK--GRHLKSNLEINLIATLINDTLNIARDIF--------------HLQSIDFRGQFNGLTL 206
            .:|.:  ...|..:.|...:....|.||::...::              ||..:         ||
Human   408 QVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIV---------TL 463

  Fly   207 RGASVIDKEDI-------------------ISNEQIESI----------------LSRPTKDAGV 236
            ..|..:..|||                   |:|...|.:                |||.
Human   464 EEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRT------ 522

  Fly   237 AAFIKYHYELLGLLRERFNFTVNFRNSRGWAGRLGNTTFRLGLLGIVMRNEADIAASGAFNRINR 301
               :|:.|:|..:...:....||    ..|.|.:|...::..::.:           |:.. ||.
Human   523 ---VKFTYDLYLVTNGKHGKKVN----NVWNGMIGEVVYQRAVMAV-----------GSLT-INE 568

  Fly   302 FAEFDTIHQSWKF-ETAFLYRYTSDLDTHGKSGNFLSPFSDRVWLF---CLLTLGAFSI-IWVLF 361
             ...:.:..|..| ||......:....|...|. ||.|||..||:.   .||.:.|.:: ::..|
Human   569 -ERSEVVDFSVPFVETGISVMVSRSNGTVSPSA-FLEPFSASVWVMMFVMLLIVSAIAVFVFEYF 631

  Fly   362 EIIDYKILRIRVNSQKLEHLNQKSSVICIKTTCIERILQTFGACCQQGLD-PNPVDRSVRFLVMT 425
            ..:.|.           .:|.:..:......|..:.|...:|......:. .||...:.:.:|..
Human   632 SPVGYN-----------RNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSV 685

  Fly   426 LFLFSLVMYNYYTSSVVGGLLSSSDQGPSTVDEITASPLKISFEDIGYYKVLFR--ESQNRSITR 488
            ...|:::....||:::...::..     ..||::|....| .|:....|...||  ...|.|..|
Human   686 WAFFAVIFLASYTANLAAFMIQE-----EFVDQVTGLSDK-KFQRPHDYSPPFRFGTVPNGSTER 744

  Fly   489 LIEKKLSSSRSLNELPIFSH----------IEDAVPYLKAG---GFAFHCEVVD 529
            .|.         |..| :.|          :|||:..||.|   .|.:...|::
Human   745 NIR---------NNYP-YMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLN 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir31a	NP_001260346.1	Lig_chan	401..624	CDD:278489	30/145 (21%)
GRIN2A	XP_016878661.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910