Protein Alignment Ir31a and glr-8

DIOPT Version :10

• Sequence 1: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 425
• Identity: 103/425 - (24%)
• Similarity: 164/425 - (38%)
• Gaps: 73/425 - (17%)

  Fly   245 ELLGLLRERFNFTVNFRNSRG--WAGRL-GNTTFRLGLLGIVMRNEADIAASGAFNRINRFAEFD 306
            |:|..:.:|.|.|.....:.|  |...| |:.|   |..|.::|.|.|:.|.||....:|....|
 Worm    98 EILKEIGKRLNLTYEILPALGSTWGEYLNGSWT---GAFGQLVRGEVDLLAGGAIMEYDRSVIAD 159

  Fly   307 TIHQSWKFE-TAFLYR----YTSD---LDTHGKSGNFLSPFSDRVWLFCLLTLGAFSIIWVLFEI 363
            ..: .::|| |..:.|    |..|   :.|        .|||..||   ::|.....|..|:|.:
 Worm   160 LTY-PFQFEPTGIMIRSPEKYEDDTLLIVT--------EPFSWEVW---VITAAVILISGVIFLV 212

  Fly   364 IDYKILRIRVNSQKLEHLNQKSSVICIKTTCIERILQTFGACCQQGLDPNPVDRSVRFLVMTLFL 428
            :...|.::      .|.:.         .|..|.|...|....||||...|...|.|.||...:|
 Worm   213 MTNIIRKV------YEEMT---------VTPFESIWVFFSIFVQQGLPEQPRSWSCRVLVALWWL 262

  Fly   429 FSLVMYNYYTSSVVGGLLSSSDQGP-STVDEITASPLKISFEDIGYYKVLFRESQNRSITRLIEK 492
            .|:.:...:|.|:|..........| ..:|::      :.....|.::::..|:.......:...
 Worm   263 ASITLSATFTGSLVALFAVDKTNVPFQNIDQL------VRLVKQGKFEIVMDENSFTRTEMIARS 321

  Fly   493 KLSSSRSLNELPIFSH-------IEDAVPYLKAG-GFAFHCEVVDAYPVISEYFDANEICDLREV 549
            ||...|.|....|.:|       |...|.:::|. |:|.      ..|:.:..|.|...|.:...
 Worm   322 KLPVYRDLWHEMIVNHKVKYVNGIARGVAFVRANPGYAL------LGPMATLNFYAYSDCKVILF 380

  Fly   550 S-GLMEVEILNWILHKNSQYTEIFKTAMCNAQEKGFVERILR--RRQI---KKPACQSLYTVYPV 608
            : |::.| .|:..|.|||.|:..|.|.:....|:||.::.:.  |..:   |...|.|. |:.|.
 Worm   381 NDGILPV-YLSIPLVKNSIYSPYFSTKIREMVERGFTQKWIADYRSYVAMQKINECNST-TIGPK 443

  Fly   609 S---LSGVLPGFVILICGFGASLLLLCLEKVYAHF 640
            |   |......|.:.:.|.|..|.|...|.::..|
 Worm   444 SYLDLKRAQGAFWVFLGGAGLGLALFVGEFIFKFF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir31a	NP_001260346.1	Lig_chan	401..623	CDD:459656	56/239 (23%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	88/368 (24%)