Protein Alignment Ir31a and Grik1

DIOPT Version :9

• Sequence 1: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_006522977.1
• Gene: Grik1 / 14805
• MGIID: 95814
• Length: 949
• Species: Mus musculus
• Alignment Length: 555
• Identity: 105/555 - (18%)
• Similarity: 209/555 - (37%)
• Gaps: 98/555 - (17%)

  Fly   130 LFPLNLNYV------GPNAQITYVNETADGYAYWDIHSKGRHLKSNLEINLIATLINDTLNIARD 188
            |.|..:|.:      |...:||: |:| ||            |:.:.::::|:.....|...:.:
Mouse   356 LGPRFMNLIKEARWDGLTGRITF-NKT-DG------------LRKDFDLDIISLKEEGTEKASGE 406

  Fly   189 IF-HL----QSIDFRGQFNGLTL------RGASVIDKEDIISNEQ--IESILSRP-----TKDAG 235
            :. ||    :.|......:||.:      |..::.|.   ::|..  :.:||..|     ..|..
Mouse   407 VSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDS---LANRTLIVTTILEEPYVMYRKSDKP 468

  Fly   236 VAAFIKYHYELLGLLRERFN-----FTVNF--------RNSRG-WAGRLGNTTFRLGLLGIVMRN 286
            :....::....|.||:|..|     :.|..        :|.:| |.          |::..::.:
Mouse   469 LYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWN----------GMVKELIDH 523

  Fly   287 EADIAASGAFNRINRFAEFDTIHQSWKFETAFLYRYTSDLDTHGKSGNFLSPFSDRVWLFCLLT- 350
            .||:|.:.......|....|..........:.|||..:  .|:....:||:|.|..:|::.||.
Mouse   524 RADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPN--GTNPGVFSFLNPLSPDIWMYVLLAC 586

  Fly   351 LGAFSIIWVLFEIIDYKILRIRVNSQKLEH-LNQKSSVICIKTTCIERILQTFGACCQQGLDPNP 414
            ||...:::|:.....|:...        .| .|..|.|:....|.:.......||..|||.:..|
Mouse   587 LGVSCVLFVIARFTPYEWYN--------PHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMP 643

  Fly   415 VDRSVRFLVMTLFLFSLVMYNYYTSSVVGGLLSSSDQGPSTVDEITASPLKISFEDI--GYYKVL 477
            ...|.|.:....:.|:|::.:.||:::...|.....:.|....:..|...||.:..:  |.....
Mouse   644 KALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTF 708

  Fly   478 FRESQNRSITRLIEKKLSSSRSLNELPIFSHIEDAVPYLKAGGFAFHCEVVDAYPVISEYFDANE 542
            |::|:    ....||..:...|..:..:..:.::.:..:....:|...|....     ||.....
Mouse   709 FKKSK----ISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSI-----EYVTQRN 764

  Fly   543 ICDLREVSGLMEVEILNWILHKNSQYTEIFKTAMCNAQEKGFVERILRRRQIKKPAC-----QSL 602
             |:|.::.||::.:.........|.|.:....|:...||:|.: .:::.:..:...|     :..
Mouse   765 -CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL-HMMKEKWWRGNGCPEEDSKEA 827

  Fly   603 YTVYPVSLSGVLPGFVILICGFGASLLLLCLEKVY 637
            ..:...::.|:   |::|..|...|:.:...|.:|
Mouse   828 SALGVENIGGI---FIVLAAGLVLSVFVAIGEFIY 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir31a	NP_001260346.1	Lig_chan	401..624	CDD:278489	41/229 (18%)
Grik1	XP_006522977.1	PBP1_iGluR_Kainate	38..431	CDD:380605	18/88 (20%)
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:389745	77/399 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910