Protein Alignment Ir31a and grin3b

DIOPT Version :9

• Sequence 1: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 682
• Identity: 126/682 - (18%)
• Similarity: 241/682 - (35%)
• Gaps: 151/682 - (22%)

  Fly    11 ILAAGEGEIIPSMEE------SVVTNFVKSLVKTKQAIVFSCLFKDFKEISLALMRINQFVSVVN 69
            :||.||.. .|:||:      .:||..:.:.|..:.              .|||::     |:||
 Frog   280 LLAYGEVS-RPTMEKFIRDAVGLVTRAISAAVHVRP--------------DLALIQ-----SMVN 324

  Fly    70 LN-----QSYSLTSILTRENYARTSVMVNARCSGSSELLFEASENRYFNKTYQWFLWGVDLEVQS 129
            .|     |:.|..|.|:|       .:.|...||.:..::.:  |...:..:.:.:|.
 Frog   325 CNDKQTKQNESSGSYLSR-------FLANTSFSGQTGQIYVS--NNLIHTEHHYRIWS------- 373

  Fly   130 LFPLNLNYVGPNAQITYVN------ETADG-----YAYWDIHSKGRHLKSNLEINLIATLINDTL 183
               |..:.:|....:|...      |..:|     ...|: .:.|...::.|.   :.||:....
 Frog   374 ---LVRDSLGDPTWVTVGGWRQGKMEVEEGLWQSRIQQWE-PAPGGFARTKLR---VVTLVEHPF 431

  Fly   184 NIARDIFHLQSIDFRGQFNGLTLRGASVIDKEDIISNEQIESILSRPTKDAGVAAFIKYH----- 243
            ...|::          ..:|....|...:|..  .:|..:..:|.........:..::|.
 Frog   432 VFTREV----------DADGSCPAGQMCLDPR--TNNSAVLDVLFEELNSPNGSVPLEYKTCCYG 484

  Fly   244 --YELLGLLRE--RFNFTVNFRNSRGWAGRLGNTTFRLGLLGIVMRNEADIAASGAFNRINRFAE 304
              .:||..|.|  ||:|.:.......:..|.|:..  .||:|.::...|.:|.:.......|...
 Frog   485 YCIDLLEKLSEDLRFDFELYIVGDGKYGARKGDRW--TGLVGDLLSGAAHMAVTSFSINSARSTV 547

  Fly   305 FDTIHQSWKFETAFLYRYTSDL-------DTHGKSGNFLSPFSDRVWLFCLLTLGAFSIIWVLFE 362
            .|       |.:.|   |::.|       ||....|.|:.|....:|:...:.|...::....:|
 Frog   548 ID-------FTSPF---YSTSLGILVRMRDTASPIGAFMWPLHWSMWVGIFVALHITALFLTFYE 602

  Fly   363 ------IIDYKILRIRVNSQKLEHLNQKSSVICIKTTCIERILQTFGACCQQGLDPNPVDRSVRF 421
                  :..:...|.::.|.. ..||     :|........:......||           :.|.
 Frog   603 WKSPFGMTPHGRNRTKIFSYS-SALN-----LCYAILFGRTVSSKTPKCC-----------TGRV 650

  Fly   422 LVMTLFLFSLVMYNYYTSSVVGGLLSSSDQGPSTVDEITA--SPLKISFEDIGY-YKVLFRESQN 483
            |:....:|.|::.:.||:::...::     |..|.:.::.  .| |:.....|: :..::..|..
 Frog   651 LMNLWAIFCLLVLSSYTANLAAVMV-----GDKTFEALSGIHDP-KLHHPSQGFRFGTVWESSAE 709

  Fly   484 RSITRLIEKKLSSSRSLNELPIFSHIEDAVPYLKAGGFAFHCEVVDAYPVISEY---FDANEICD 545
            :.|.:...:..:..|..: :|..|   |.|..||......:..::|  ..:.:|   .|::  |.
 Frog   710 QYIKKSFPEMHNYMRKFS-VPATS---DGVHLLKTDPPTLNAFIMD--KALLDYEVSIDSD--CK 766

  Fly   546 LREVSGLMEVEILNWILHKNSQYTEIFKTAMCNAQEKGFVERILRRRQIKKPACQSLYTVYPVSL 610
            |..:.....:|.....|.:||..|......:...:..||::.:..:.....|..:.:|.|.....
 Frog   767 LLTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSGFMDTLHDKWYKMVPCGKRVYAVTETLQ 831

  Fly   611 SGV--LPGFVILIC-GFGASLLLLCLEKVYAH 639
            .|:  ..|..:|:| ||..|||...:|:|..|
 Frog   832 MGIYHFSGLFVLLCIGFCGSLLTSLMERVVYH 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir31a	NP_001260346.1	Lig_chan	401..624	CDD:278489	41/231 (18%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	32/160 (20%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	77/453 (17%)
		Lig_chan	582..848	CDD:395014	49/296 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910