Protein Alignment Ir31a and gria3

DIOPT Version :9

• Sequence 1: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001106494.1
• Gene: gria3 / 100127683
• XenbaseID: XB-GENE-1010483
• Length: 887
• Species: Xenopus tropicalis
• Alignment Length: 675
• Identity: 135/675 - (20%)
• Similarity: 236/675 - (34%)
• Gaps: 156/675 - (23%)

  Fly    20 IPSMEESVVTNFVKSLVKTKQAIVFSCLFKDFKEISLALMRINQFVSVVNLNQSYSLTSILTRE- 83
            |.:.|..:|..|::..|:..:        ::|.|..               |.....||.||.:
 Frog   266 IVNNENPIVQQFLQRWVRLDE--------REFPEAR---------------NTPLKYTSALTHDA 307

  Fly    84 --------NYARTS-VMVNARCSGSSELLFEASENRYFNKTYQWFLWGVDLEVQSLFPLNLNYVG 139
                    .|.|.. |.|:.|.|....|.         |....| ..|:|:| ::|..:.:..:.
 Frog   308 VLVIAEAFRYLRRQRVDVSRRGSAGDCLA---------NPAVPW-SQGIDIE-RALKMVQVQGMT 361

  Fly   140 PNAQI-TY---VNETADGY----------AYWDIHSKGRHLKSNLEINLIATLINDTLNIARDIF 190
            .|.|. ||   .|.|.|.|          .:|:.:.:..........|..:::.|.|:.:.
 Frog   362 GNIQFDTYGRRTNYTIDVYEMTATKPRKVGHWNEYERFVPAPDQQPTNESSSVENKTIIVT---- 422

  Fly   191 HLQSIDFRGQFNGLTLRGASVIDKED---IISNEQIE----SILSRPTKDAGVAAFIKYHYELLG 248
                         ..|....|:.|::   :..|::.|    .:.|...|..|    |||...::
 Frog   423 -------------TILENPYVMKKKNHELLDGNDKYEGYCVDLASEIAKHVG----IKYKLSIV- 469

  Fly   249 LLRERFNFTVNFRNSRGWAGRLGNTTFRLGLLGIVMRNEADIAASGAFNRINRFAEFDTIHQSWK 313
               |...:......::.|.|.:|...:          ..||||.:.....:.|....|
 Frog   470 ---EDGKYGARDPETKIWNGMVGELVY----------GRADIAVAPLTITLVREEVID------- 514

  Fly   314 FETAFLYRYTSDL---DTHGKSG--NFLSPFSDRVWLFCLLTLGAFSIIWVLFEIIDYKILRIRV 373
            |...|:....|.:   ....|.|  :||.|.:..:|: |::    |:.|.|  .::.:.:.|...
 Frog   515 FSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM-CIV----FAYIGV--SVVLFLVSRFSP 572

  Fly   374 NSQKLEHLNQ------------KSSVICIKTTCIERILQTFGACCQQGLDPNPVDRSVRFLVMTL 426
            ....||..::            :..:       ...:..:.||..|||.|.:|...|.|.:....
 Frog   573 YEWHLEDTDEARDPQNPPDPPNEFGI-------FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVW 630

  Fly   427 FLFSLVMYNYYTSSVVGGLLSSSDQGPSTVDEITASPLKISFE--DIGYYKVLFRESQNRSITRL 489
            :.|:|::.:.||:::...|.......|....|..|...:|::.  |.|..|..||    ||...:
 Frog   631 WFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFR----RSKIAV 691

  Fly   490 IEKKLSSSRSLNELPIFSHIEDAVPYLK--AGGFAFHCEVVDAYPVISEYFDANEICDLREVSGL 552
            .||..|..:|..........:|.|..::  .|.|||..|     ..::||.:..:.||..:|.|.
 Frog   692 YEKMWSYMKSAEPSVFTKTTDDGVARVRKSKGKFAFLLE-----STMNEYIEQRKPCDTMKVGGN 751

  Fly   553 MEVEILNWILHKNSQYTEIFKTAMCNAQEKGFVERILRRRQIKKPAC-----QSLYTVYPVSLSG 612
            ::.:.......|.|........|:....|:|.::::..:....|..|     .|......:|||.
 Frog   752 LDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSN 816

  Fly   613 VLPGFVILICGFGASLLLLCLEKVY 637
            |...|.||:.|.|.::::..:|..|
 Frog   817 VAGVFYILVGGLGLAMMVALIEFCY 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir31a	NP_001260346.1	Lig_chan	401..624	CDD:278489	57/231 (25%)
gria3	NP_001106494.1	Periplasmic_Binding_Protein_Type_1	29..400	CDD:324556	34/167 (20%)
		PBP2_iGluR_AMPA	416..798	CDD:270433	87/446 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000