DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31717 and Plpp7

DIOPT Version :9

Sequence 1:	NP_001260317.1	Gene:	CG31717 / 318911	FlyBaseID:	FBgn0051717	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_663496.1	Gene:	Plpp7 / 227721	MGIID:	2445183	Length:	271	Species:	Mus musculus

Alignment Length:	196	Identity:	63/196 - (32%)
Similarity:	104/196 - (53%)	Gaps:	18/196 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ALKYLLEKDVQVSKHFVVAVSNLSFFKSLRIHSRFLEISCDGIAWFVSWIAFIWLLSSKSLYQMQ 71
            |...||..|:.:||...|.....:.:.|.|...:.:.|:..||.|....|  :.|:.|.:|...:
Mouse    81 AFNSLLAIDICMSKRLGVCAGRAASWASARSMVKLIGITGHGIPWIGGTI--LCLVRSSTLAGQE 143

  Fly    72 V--NMLFGLILDVVIVAVLKALVRRRRPVASK----DMLTIGPDKFSFPSGHASRAFFVLLFFAK 130
            |  |:|..|:||::.||.::.|::||.|..:.    |.||:  |.::||:||||||..|..||..
Mouse   144 VLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPGLLDYLTM--DIYAFPAGHASRAAMVSKFFLS 206

  Fly   131 LYPLHIIFLMP----VTAWAVSVAISRLILQRHYILDICAGAAIGVLEALIVGLLWISEETAFSI 191
                |::..:|    :..||..|.:||:::.||:|.|:.:|..||..:..:|.|:|:|..|...:
Mouse   207 ----HLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYFQFRLVELVWMSSNTCQML 267

  Fly   192 V 192
            :
Mouse   268 I 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31717	NP_001260317.1	PAP2_containing_2_like	23..179	CDD:239485	52/165 (32%)
CG31717	NP_001260317.1	PgpB	<49..182	CDD:223743	49/142 (35%)
Plpp7	NP_663496.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..68
		Interaction with MTOR. /evidence=ECO:0000269\|PubMed:19704009	70..91		4/9 (44%)
		PAP2_containing_2_like	97..255	CDD:239485	52/165 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831541
Domainoid	1	1.000	84	1.000	Domainoid score	I8261
eggNOG	1	0.900	-	-		E1_KOG4268
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4839
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49210
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002759
OrthoInspector	1	1.000	-	-		otm44153
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14969
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3913
SonicParanoid	1	1.000	-	-		X1845
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.890