DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43672 and ABCA5

DIOPT Version :9

Sequence 1:	NP_788912.3	Gene:	CG43672 / 318910	FlyBaseID:	FBgn0263747	Length:	1690	Species:	Drosophila melanogaster
Sequence 2:	NP_001326002.1	Gene:	ABCA5 / 823930	AraportID:	AT3G47760	Length:	936	Species:	Arabidopsis thaliana

Alignment Length:	747	Identity:	158/747 - (21%)
Similarity:	307/747 - (41%)	Gaps:	156/747 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 NVDESLNGLPTVLNFAIIMPSELRNYEDT-WIGDSWKETTTLMDRDVAEEDEFDEDGYTDYMGEG 217
            |::|.:|.:....:   :|.:::.|:..| |...::|  ..|.||.|            .|:.
plant   252 NLEEIINEVAAAYD---LMDTDINNFNVTIWYNSTYK--GDLRDRRV------------KYVR-- 297

  Fly   218 FVP----LQYHISMQFLRATASK-----VEKLPKVVMRRFNENPNVLLSEGIGTSVVLLILLGFM 273
             ||    |..:..::||:.:.:|     |:::||...|...|..: |:.....|.|:||     :
plant   298 -VPRSVNLVSNAYLEFLQGSGTKMLFDFVKEMPKQETRLRLEMAS-LIGPIFFTWVILL-----L 355

  Fly   274 FPVTILTTLIVEERELGQRYMLKILNASATLQMAAWFFNVFTHFLITSLLITILLKI-------- 330
            ||| :||:|:.|:::     .|:|:.....|....::...:.:||..|::..|.|.|
plant   356 FPV-MLTSLVYEKQQ-----HLRIIMKMHGLGDGPYWMITYAYFLAISIVYIICLMIFGSAIGLK 414

  Fly   331 --EWNGATAAVNKCPWPILLCFLISYGC--SVTSLIILMTSAMRRSRVAMVMAPIIWILLALPLL 391
              .:|..:           :.|:..:.|  ...|:..|::||..:...|.| |..:::.
plant   415 FFRFNDYS-----------IQFIFYFLCINLQISIAFLVSSAFSKIETASV-AAYLYVF------ 461

  Fly   392 SKKELLSDGPDVFYGFA-TVLLCNVSFSRGLSKIFYIEDYTLGVTI-------GKYMFYR----- 443
                    |..:...|. ..||..:||.|  |.|:.:|.|. |.::       .:|.|.|
plant   462 --------GSGLLGAFLFQFLLEGLSFPR--SWIYIMELYP-GFSLYRGLYEFSQYAFKRNLNGS 515

  Fly   444 --VSKSDFGIFVPIVCFYVQTI--FCTLLAMIFEN-------NAYFWLAIRVKNLLKKYHATRSA 497
              :...||........||:..:  |..|:|..:.:       :.:|:|  :.:|..||   :.|.
plant   516 GGMKWKDFNDSAMEEIFYIIIVEWFVALIAAYYTDKISSSGIDPFFFL--KNQNPFKK---SPSP 575

  Fly   498 VGRLKRQIP---------EVSFSKTSAEALI------------EFRGVW-------QKYSNSTYV 534
            .| |:||:.         :|:..:...|.|:            ..:.|:       ||.:
plant   576 YG-LQRQVSAIAIEMEKLDVAHERVKVEQLMLETSTGHAIVCDNLKKVYPCRDGNPQKMA----- 634

  Fly   535 VQDITLNVYAGEVVALLGHNASGKSTIIKMLYGRTRPKLGEIYLSGFNIVTQRKEALKNSSISMS 599
            |:.::|.|.:||...:||.|.:||::.|.|:.|..:|..|..::.|.:|.........:..:...
plant   635 VRGLSLAVPSGECFGMLGPNGAGKTSFINMMTGLMKPTSGAAFVHGLDICKDMDIVYTSIGVCPQ 699

  Fly   600 YKTLFTELVVLDHLVFLSRLRGLSKTEAKLEAKALLRYLKLEDWEKTLVNDLTIGQ-----RRVL 659
            :..|:..|...:||:|..||:.|..::..   :|:...||..:..:..|.|...|:     :|.|
plant   700 HDLLWETLTGREHLLFYGRLKNLKGSDLD---QAVEESLKSVNLFRGGVADKPAGKYSGGMKRRL 761

  Fly   660 QFLCAFAGGNQIVILDKPFDGIDEQRTSLFYSLILDQKKNRSIFFTSNNQKVASGIADRIFVLSK 724
            ....:..|..::|.:|:|..|:|.......::.|...|.:.:|..|:::.:.|..:.||:.:...
plant   762 SVAISLIGSPKVVYMDEPSTGLDPASRRSLWTAIKRAKNHTAIILTTHSMEEAEFLCDRLGIFVD 826

  Fly   725 GKLQAFGTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFMATFIPEIEMDSILADCASFLVKHKYH 789
            |:||..|..|:|......||.|.:....:.. |||...:....|..:....:|....|.:. |..
plant   827 GRLQCVGNPKELKARYGGSYVLTMTTPSEHE-KDVEMLVQDVSPNAKKIYHIAGTQKFEIP-KEE 889

  Fly   790 TELINLIENLARLKNDLNVYSFEIHECSIDDI 821
            ..:..:.:.:.:.|::..|:::.:.:.:::|:
plant   890 VRISEVFQAVEKAKDNFRVFAWGLADTTLEDV 921

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	115/534 (22%)
		ABC_subfamily_A	519..737	CDD:213230	54/241 (22%)
		P-loop_NTPase	1330..1517	CDD:422963
ABCA5	NP_001326002.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920