Protein Alignment CG43672 and ABCA4

DIOPT Version :10

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: NP_001319703.1
• Gene: ABCA4 / 823929
• AraportID: AT3G47750
• Length: 937
• Species: Arabidopsis thaliana
• Alignment Length: 847
• Identity: 174/847 - (20%)
• Similarity: 330/847 - (38%)
• Gaps: 199/847 - (23%)

  Fly    98 IRVAFAPN-SNAALRRLMGDALGKLSMSEDKIVDFENCNDMRIHA-----------------ASE 144
            :..:||.| |:..||.|..:.||.:|.:     |:.|..|..||:                 :..
plant   152 LSTSFAVNSSDHFLRNLAYNVLGTISEA-----DYTNYLDPGIHSDLPIFQIRPYCTPTTNLSFS 211

  Fly   145 HYLASVCFRNVDESLNGLPTVLNFAIIMPSEL------RNYE-------------DT-------- 182
            .....:.|......:.||....|.::.:..|:      .|:|             ||
plant   212 FRQPPITFHKEVRCVQGLNLWRNNSVEVNDEIFKGYRQGNHEEIINEVAAAYDLLDTDRNKFNVT 276

  Fly   183 -WIGDSWKETTTLMDRDVAEEDEFDEDGYTDYMGEGFVPLQYHISM------QFLRATASK---- 236
             |...|:|....:.||.|.                 :|.:...::|      :|||...:|
plant   277 IWYNSSYKGNFKVQDRRVK-----------------YVRVPRSVNMVSNAYLRFLRGPGTKMLFD 324

  Fly   237 -VEKLPK--VVMRRFNENPNVLLSEGIGTSVVLLILLGFMFPVTILTTLIVEERELGQRYMLKIL 298
             |:::||  .::|       |.::..|| .:.|..::..:||| ||.:|:.|:::     .|:|:
plant   325 FVKEMPKQESMLR-------VDIASVIG-PIFLTWVIVLLFPV-ILNSLVYEKQQ-----HLRII 375

  Fly   299 NASATLQMAAWFFNVFTHFLITSLLITILLKI----------EWNGATAAVNKCPWPILLCFLIS 353
            .....|....::...:.:||..|.|..|.|.|          .:|..:           :.|:..
plant   376 MKMHGLGDGPYWMITYAYFLAISTLYIICLMIFGSAIGLKFFRFNDYS-----------IQFIFY 429

  Fly   354 YGC--SVTSLIILMTSAMRRSRVAMVMAPIIWILLALPLLSKKELLSDGPDVFYGFA-TVLLCNV 415
            :.|  ...|:..|::||..:...|.| |..:::.              |..:..||. ..:|..:
plant   430 FLCINLQISIAFLVSSAFSKVETASV-AAYLYVF--------------GSGLLGGFLFQFMLEGL 479

  Fly   416 SFSRGLSKIFYIEDYTLGVTI--GKYMF--YRVSK----SD------FGIFVPIVCFYVQTI--F 464
            ||.||.  ||.:|.|. |.::  |.|.|  |.:.:    ||      |........||:..|  |
plant   480 SFPRGW--IFVMELYP-GFSLYRGLYEFSQYALKRQLNGSDGMKWKYFSDSAMDEVFYIIIIEWF 541

  Fly   465 CTLLAMIFENNAYFWLAIR---------VKNLLKKYHA-TRSAVGRL----------------KR 503
            ..|:|      ||:...:.         :|||:||..: .|.::.||                :.
plant   542 LALIA------AYYMDRVSSSAKDPFLFLKNLIKKSPSPQRHSLQRLGSSVSVEMEKLDVVEERA 600

  Fly   504 QIPEVSFSKTSAEALI--EFRGVWQKYSNS--TYVVQDITLNVYAGEVVALLGHNASGKSTIIKM 564
            ::.::....:::.|::  :.:.|:.....:  ...|..:::.|..||...:||.|.:||::.|.|
plant   601 KVEQLMLESSTSHAIVCDKLKKVYPGRDGNPPKMAVGGLSIAVPPGECFGMLGPNGAGKTSFINM 665

  Fly   565 LYGRTRPKLGEIYLSGFNIVTQRKEALKNSSISMSYKTLFTELVVLDHLVFLSRLRGLSKTEAKL 629
            :.|..:|..|...:...:|.....:...:..:...:..|:..|...:||:|..||:.|..::..
plant   666 MTGLVKPTSGTALVESLDICQDMDKVYTSMGVCPQHDLLWETLTGREHLLFYGRLKNLKGSDLN- 729

  Fly   630 EAKALLRYLKLEDWEKTLVNDLTIGQ-----RRVLQFLCAFAGGNQIVILDKPFDGIDEQRTSLF 689
              :|:...||..:..:..|.|...|:     :|.|....:..|..::|.:|:|..|:|.......
plant   730 --QAIEESLKSVNLSREGVADKPAGKYSGGMKRRLSVAISLIGSPKVVYMDEPSTGLDPASRRSL 792

  Fly   690 YSLILDQKKNRSIFFTSNNQKVASGIADRIFVLSKGKLQAFGTVKKLCRMLNESYRLIIFGNEKC 754
            ::.|...||:.:|..|:::.:.|..:.||:.:...|:||..|..|:|......||.|.:..:.:.
plant   793 WTAIKGAKKHTAIILTTHSMEEAEFLCDRLGIFVDGRLQCVGNPKELKARYGGSYVLTMTTSSEH 857

  Fly   755 SFKDVYAFMATFIPEIEMDSILADCASFLVKHKYHTELINLIENLARLKNDLNVYSFEIHECSID 819
            . |||...:....|..:....:|....|.:. |....:..|.:.:.:.|.:..|:::.:.:.:::
plant   858 E-KDVEMLIQDVSPNAKKIYHIAGTQKFEIP-KDEVRIAELFQAVEKAKGNFRVFAWGLADTTLE 920

  Fly   820 DI 821
            |:
plant   921 DV 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	114/529 (22%)
		ABC_subfamily_A	519..737	CDD:213230	51/226 (23%)
		P-loop containing Nucleoside Triphosphate Hydrolases	1330..1517	CDD:476819
ABCA4	NP_001319703.1	rim_protein	<346..>937	CDD:130324	131/623 (21%)
		ABC_subfamily_A	619..840	CDD:213230	51/223 (23%)