Protein Alignment CG43672 and abca8

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: XP_031749971.1
• Gene: abca8 / 549630
• XenbaseID: XB-GENE-1005441
• Length: 1619
• Species: Xenopus tropicalis
• Alignment Length: 1625
• Identity: 325/1625 - (20%)
• Similarity: 629/1625 - (38%)
• Gaps: 345/1625 - (21%)

  Fly   211 TDYMGEGFVPLQYHISMQFLRAT---------ASKVEKLPKVVMRRFNENPNVLLSEGIGTSVVL 266
            |.|....|:.||..|....:..|         ||.|....|..:..|.:..:      |||.:.|
 Frog   171 TYYWSRQFLSLQASIDSAIIELTSNHSVWDNMASVVTVRMKSTVASFRQYFH------IGTFIFL 229

  Fly   267 LIL--LGFMFPVTILTTLIVEERELGQRYMLKILNASATLQMAAWFFNVFTHFLITSLLITILLK 329
            :.:  :..|:.:::..|.  |.||:  |.:||::.........:|......:.||.:.|:|::.|
 Frog   230 MPMCYVSLMYLLSLYITR--ERREM--RELLKMMRLKDLAFWLSWGLLYLFYILILANLMTLVTK 290

  Fly   330 IEWNGATAAVNKCPWPILLCFLISYGCSVTSLIILMTSAMRRSRVAMVMAPIIWILLALPLLSKK 394
                 |...| :..:.|::...:.||.::.|...::::..|..|...:..  .:|.|.|..|...
 Frog   291 -----AFVFV-QSSYGIIMFLFVFYGIALMSFTFMLSALFRSPRATAIAG--FFITLFLSALGLV 347

  Fly   395 ELLSDGPDVFYGFATVLLC---NVSFSRGLSKIFYIEDYTLGVTIGKYMFYRVSKSDFGIFVPIV 456
            .|..|.|...    .|||.   ..:|:.||::..::|....||     .|..::.....:....:
 Frog   348 LLRKDFPQAL----AVLLSIFPQFAFAVGLTESVHMESDLQGV-----YFSDMAGDSSHVLSSFI 403

  Fly   457 CFYVQTIFCTLLAMIFEN----------------NAYFWLAIRVKNLLKKYH-ATRSAVGRLKRQ 504
            ...:.:||...|.:.||.                .:.:|...::..:|.:.. :..|::|....:
 Frog   404 SLALDSIFYMGLTLYFEKVLADKHGLKYEPFFFMKSSYWSKKKLSPVLTQTEDSGESSMGEFFER 468

  Fly   505 IPEVSFSKTSAEALIEFRGVWQKY---SNSTYVVQDITLNVYAGEVVALLGHNASGKSTIIKMLY 566
            :|.....|.:    |....|.:||   ..:...::.:.||:|.|::.|||||:.:||:|::.:|.
 Frog   469 VPIDLHGKEA----IRINKVMKKYCDQDKNIEALRGLDLNIYEGQITALLGHSGAGKTTLLNILS 529

  Fly   567 GRTRPKLGE--IYLSGFNIVTQRKEALKNSSISMSYKTLFTELVVLDHLVFLSRLRGLSKTEAKL 629
            |......|.  :|....:.:...:|..|.:.........|..|.|.::|...::::|:.:.:.|.
 Frog   530 GLCPASDGSATVYSYKLSDMQHLEEIKKRTGFCPQSDVKFNPLTVKENLTVFAKIKGIPRKQIKH 594

  Fly   630 EAKALLRYLKLEDWEKTLVNDLTIGQRRVLQFLCAFAGGNQIVILDKPFDGIDEQRTSLFYSLIL 694
            :.:.:|..|::.|.|....::|:.||||.|....|..|..|:::||:|..|:|.......::::.
 Frog   595 KVQKVLSDLQMNDIENVEADNLSGGQRRKLTLGIALLGDPQVLLLDEPTAGLDPCSRHHIWTILK 659

  Fly   695 DQKKNRSIFFTSNNQKVASGIADRIFVLSKGKLQAFGTVKKLCRMLNESYRLIIFGNEKCSFKDV 759
            :.|.:|...|::.....|..:|||..|:|.|:|:..|:...|.|.....|.|.:..:..|..:.:
 Frog   660 ENKADRVTLFSTQFMDEADILADRKAVISNGRLKCVGSSLFLKRKWGIGYHLRMQVSPTCDVELM 724

  Fly   760 YAFMATFIPEIEMDSILADCASFLVKHKYHTELINLIENL-ARLKNDLNVYSFEIHECSIDDILA 823
            .:.:...:|:.::.:...:..::.:..:......:|..:| .::.|  ::.::.:...::||:..
 Frog   725 TSIIKQHVPDAKLTAQNEEELTYTLPFENMDAFPDLFLHLDGQVGN--SIVNYGVSMTTLDDVFL 787

  Fly   824 SLYTRDKSTLEFGQPGL--------------------QTLLASRQQSAKRRFIIPTMYLLEELRQ 868
            .|  ..:..:|.|..|:                    ..||.|...||       |:..|...||
 Frog   788 KL--EGEGEIEKGDYGVFSPDSGAPEDKDCFSAGMEDSLLLMSDSGSA-------TLSGLSLWRQ 843

  Fly   869 LLIA-----------DTRN----------WFLPILKLTLP----SLVVVWTLSMPYFWHNCRQPG 908
            .::|           |::.          :.:||:..|:.    ..|:.|.|:...::.:.....
 Frog   844 QVLAIARVRLLKLKHDSKTFRSILILLALFIIPIIMTTIVIKIFHKVITWELTPSLYFQHPEDRF 908

  Fly   909 HITFP----MSDHGDGI-----------ILMQKDTLDSELLVASEMY-AKVGVTEVDKTVDITTF 957
            |..:.    .::.|..|           |.:|  .::.|..:.:..| ..:.|::..|.... |.
 Frog   909 HRYYTDLQIYNNTGSSIEDFLGALKEQNIAVQ--VVNGEYDMETTFYRGAIEVSQATKGYGF-TI 970

  Fly   958 IYNYEYKNSL------LSDADIMEAVIFSNVQ-IEVLFNTKWPHTAPDSLAQALNSLAVAFIDGD 1015
            :.|.:.:|:|      :|:|.:|   ||::.: |.|     |.|...:.|.:...|  |.|..|.
 Frog   971 VGNPKAQNALPVLVNIISNALLM---IFNSTEHIRV-----WNHPVTEYLVEDFES--VTFYSGF 1025

  Fly  1016 AGIKVELEVLPFSTIHTLQ-------LHLNIDGYDLIFASCLSFCFCFIWSIP----LLHMTLSR 1069
            ..:.....:.|...:.:::       ..|.|.|   ||.|...|....: .:|    ||.:.::.
 Frog  1026 MLLLFASGLAPHFAMSSIEDRRIKARTQLRISG---IFPSAYWFGQALV-DVPLYWILLFLMVAI 1086

  Fly  1070 DGRYNYVELIAGMPTIVLIVAFLIYELLVVLLALFPINIAVIFFHWDLLMDSNIHIYSVYVMFII 1134
            ...:|...:.:.:|.|:||...:.|...|||.      :.||.|   :......|.....:.|:|
 Frog  1087 LFSFNSQVIFSFVPAIILITGVIGYGAAVVLY------VYVISF---VFGRGKSHHDGWSIFFVI 1142

  Fly  1135 AACVFSLNILITIMPISDMPFVYLKVLLAYSLGILVYIAVKELRPFTNPNTAHFLLLDFHPFYAL 1199
            :|.:               |.:.|.|:..|::||                 ..||||.
 Frog  1143 SAFI---------------PMILLDVVSTYAVGI-----------------TFFLLLP------- 1168

  Fly  1200 LHNLMRIASISEKIWLCSDRQIYETSVYADQCNTIPNCCDDDAQEFYHLRYLCCVYLLL----VV 1260
                   ||....|..|.|...::.|...|:                ||.||...:|.:    |:
 Frog  1169 -------ASTLSGIIRCIDVYHFDRSTLEDE----------------HLLYLFFPFLHIVIFSVI 1210

  Fly  1261 VWISIFIF----LKSHMVKRRPRQPKYFWDSDPDSKYDQNILHIMEPSELENTWIHEKSRVSTLE 1321
            :|:...:|    ||:::..|:              |..:|...:.|.::.|.....|:.::|:..
 Frog  1211 LWVLERVFGMRSLKTNLFYRK--------------KVQKNQEELGEDTDEEVLAERERVKMSSTT 1261

  Fly  1322 RNHIESKALHVEHL---------SVFF--GLKAAIKHIDFMVNRYQVMSVFGANGTGKSVLLKTI 1375
            .|..|...:.|:.|         ..||  ..|||.|:|.|.|.:.:|:.:.|.||.||:..:..:
 Frog  1262 NNMEEKPIIIVDSLRKEYKVKKGKSFFKKNKKAATKNISFCVRKGEVLGLLGPNGAGKTTSIYML 1326

  Fly  1376 LGIYTPSSGRIISSKTVPFKSKD--LDSCHMVGYSAQEFQTMQLMTILETWDLILRIRRSKQISF 1438
            .|...|::|.::...|.|.||::  .|....:||..|:......:|:.:..::...::..|:...
 Frog  1327 AGEIRPTAGEVLLCGTDPDKSQNSQYDPTGSLGYCPQDNPLWPNLTVKQHLEIYAAVKGLKKKDA 1391

  Fly  1439 RAEATKLCKIFGLYKYRFNSLSICSQGVLKRLSLGIALMSDAELILLDDPFTHLDIVSQRSMLHI 1503
            .....::.:...|.::...:....|.||.:::...|:::.:..::|||:|.|.||...|:.:...
 Frog  1392 ETAIKRVSEALELKEHLEKAARKLSAGVSRKVCFAISMLGNPNIVLLDEPSTGLDPKGQQRLWRA 1456

  Fly  1504 IHD-LRRRGHSIIYTCSDTAYSTPAL----RMATLSYPGIAVIGEREEMQQNYYSSYYMVETRIH 1563
            |.. .|.:....|.|   |.|...|.    |:|.:....:..||..::::..:...|.:
 Frog  1457 IRSAFRNKDRGAILT---THYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKGYLL------ 1512

  Fly  1564 LAELGSPIDFDSQSTEAKEDRAGTTGTLLRHKHQEFSAAFTDSA--DRWKYLKLCGV-IENVFPH 1625
                           |.|...:.....:    |.|....|..:|  ||:..|.:..: :|||
 Frog  1513 ---------------EIKVKNSNQVDQI----HNEIIQIFPHAARQDRFSSLLVYKIPVENV--- 1555

  Fly  1626 AIIKNVSFPRVCFWLSSHMYPMSRIVDTLHRNKQDF----YSFSVSQPSVNSVFLSIHRQKSNKD 1686
                               ..:|:....|...|:.:    |||  |||::..||:.:.:::..:|
 Frog  1556 -------------------QSLSKAFLDLEEAKRAYNIEEYSF--SQPTLTQVFIELTKEQERED 1599

  Fly  1687  1686
             Frog  1600  1599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	108/492 (22%)
		ABC_subfamily_A	519..737	CDD:213230	58/222 (26%)
		P-loop_NTPase	1330..1517	CDD:422963	46/200 (23%)
abca8	XP_031749971.1	rim_protein	<225..1601	CDD:130324	311/1565 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010