Protein Alignment CG43672 and Abca14

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: XP_038957098.1
• Gene: Abca14 / 365362
• RGDID: 1561491
• Length: 1691
• Species: Rattus norvegicus
• Alignment Length: 1879
• Identity: 405/1879 - (21%)
• Similarity: 751/1879 - (39%)
• Gaps: 411/1879 - (21%)

  Fly     9 FCLLVWKNFQKQKHNKLVLILSLVLPVMSSLFLLFIRSSSDSNMRDYSIRAEAELLEFSWSSLIG 73
            |.:|:||||..:......|::.::|     :||||:                       |:..:.
  Rat    20 FLVLLWKNFLLKSRKVFGLVVEIIL-----IFLLFV-----------------------WTLTVR 56

  Fly    74 KIQERRAKMASKQRNFTTNVFIP-------------DIRVAFAPNSNAALRRLMGDALGKLSM-- 123
            :|        ||::.....:|.|             |..:|:.|:.:.|.|.:.......|:.
  Rat    57 RI--------SKKKFIPAMIFNPIPLTLPGFLNQNFDYELAYVPSDSNAARNITEMVKKDLNFNF 113

  Fly   124 ---------SEDKIVDFENCNDMRIHAASEHYLASVCFRNVDESLN-GLPTVLNFA--------- 169
                     |.:|.:.:|:        .:||.||::.|.:..::.| .||..:.::
  Rat   114 KVQGFSSEESFEKYIKYED--------KAEHVLAAIVFDHKFKTSNEPLPLQVKYSLRFGRMYDP 170

  Fly   170 --IIMPSELRNYEDTW-IGDSWKETTTLMDRDVAEEDEFDEDGYTDYMGEGFVPLQYHISMQFLR 231
              ::.||| |..|..| ....:....:|..|:|.|.|    .|...|:.|||:.:|:.:....:.
  Rat   171 ENVLKPSE-RQKETEWNTSILFPSVPSLGPRNVLEND----GGNPGYIREGFLLVQHSVDKAIMM 230

  Fly   232 ATASKVEKL----PKVVMRRFNENPNVLLSEGIGTSVVLLILLGFMFPVTIL-----------TT 281
            ..:.:..:.    ..:..||| ..|..:....:.|.:|       |||.|||           .|
  Rat   231 HHSGRAAEAMFANTTIYARRF-PYPAFIHDNFLWTFIV-------MFPWTILFTFTQMALDIIGT 287

  Fly   282 LIVEERELGQRYMLKILNASATLQMAAWFFNVFTHFLITSLLITIL-LKIEWNGATAAVNKCPWP 345
            :::|:.:..:.|.|.:..::|.|.::.:...:..:|:|..||..|| |||    ....|.:...|
  Rat   288 IMLEKEKRLKEYQLMVGLSNAMLWVSYFITFLLMYFIIICLLCGILFLKI----THERVFQHSDP 348

  Fly   346 I-----LLCFLISYGCSVTSLII--LMTSAMRRSRVAMVMAPIIWILLALPL-----------LS 392
            :     .|||.||      |:::  ::::...|:.:|..:|..:..|...|.           ||
  Rat   349 LFIAFYFLCFAIS------SMLLGFMISTFFNRASLATSIAGFLHFLTFFPYLIVFSLYDQTSLS 407

  Fly   393 KKELLSDGPDVFYGFATVLLCNVSFSRG--------LSKIFYIEDYTLGVTIGKYMFYRVSKSDF 449
            .|..|....:....|.|.|:|.:.. :|        .:|:...:|.||...||.::|   |...:
  Rat   408 GKLALCLITNTALAFGTDLICKLEM-KGHGAQWYNFATKVNPDDDLTLAHIIGMFLF---SAFLY 468

  Fly   450 GIFVPIVCFYVQTIFCTLLAMIFENNAYFWLAIRVKNLLKKYHATRSAVGRLKRQI---PEVSFS 511
            |    :|.:||..:|.....:....|.:         |.|.|.....|:.|.:.|:   |...|.
  Rat   469 G----LVAWYVDAVFPGKYGVPKPWNFF---------LQKTYWFGEPALSREESQVSDLPPSDFM 520

  Fly   512 K---TSAEALIEFRGVWQKYS--NSTYV-VQDITLNVYAGEVVALLGHNASGKSTIIKMLYGRTR 570
            :   ...||.|:.:.::::::  |||.: |:|::||:|.|::..|||||.:||:|.:.:|.|...
  Rat   521 EPEPVDLEAGIQIQHLYKEFTLKNSTLMAVKDLSLNLYEGQITVLLGHNGAGKTTTLSILTGLYL 585

  Fly   571 PKLGEIYLSGFNIVTQRKEALKNSSISMSYKTLFTELVVLDHLVFLSRLRGLSKTEAKLEAKALL 635
            |..|::|:||::|.:...:..|:..:......||..|.|.:||.|...::|:|.|....|...:|
  Rat   586 PTKGKVYISGYDISSDMVQVRKSLGLCPQDDLLFPLLTVSEHLYFYCVIKGISSTNRPREIHRML 650

  Fly   636 RYLKLEDWEKTLVNDLTIGQRRVLQFLCAFAGGNQIVILDKPFDGIDEQRTSLFYSLILDQKKNR 700
            ....|.....|:..||:.|.:|.|..:.|..|..::||||:|..|:|.......:.|:...||:|
  Rat   651 TSFGLLQKSNTMSKDLSGGMKRKLSIIIALIGDTKVVILDEPTSGMDPVSRRAIWDLLQHYKKDR 715

  Fly   701 SIFFTSNNQKVASGIADRIFVLSKGKLQAFGTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFMAT 765
            :|..|:::...|..:.|||.:|..|.|:..|:...|.::....|.|:|..........:...:..
  Rat   716 TILLTTHHMDEADVLGDRIAILVMGVLKCCGSSLFLKKLYGVGYHLVIVKTPDSDDGKISQLIKN 780

  Fly   766 FIPEIEMDSILADCASFLVKHKYHTELINLIENLARLKNDLNVYSFEIHECSIDDI------LAS 824
            :||..||::.:|...||::..::......|..:|...:.:|.:..|.:...::|::      ||.
  Rat   781 YIPTAEMETNVAAELSFILPKEHTHRFAELFTDLEERQEELGISGFGVSMTTMDEVFFKVSNLAD 845

  Fly   825 LYTRDKSTLEFGQPGLQTLLASRQQSAKRRFIIPTMY--------------------LLEELRQL 869
            |    |...|..| ...|:..|..:: .....:|..:                    .:::.|.:
  Rat   846 L----KLNTEIAQ-SASTVNPSTSEN-NENMNVPRNFERSGYSGRYSDSSFNAGWPLYMQQFRAM 904

  Fly   870 LIA----DTRNWFLPILK-LTLPSLVVVWTLSM-------PYFWHNCRQPGHITFPMSDHGDGII 922
            .|.    ..|||.|.:|: |.|..|..|....:       |....:..|.|..|.|.|..||. .
  Rat   905 FIKRVMFSWRNWKLLLLQLLALQGLTYVLIKGIGFSVPKEPARVMDLEQYGETTVPFSVSGDP-P 968

  Fly   923 LMQKDTLDSELLVASEMYAKVGVTEVDKTVDITTFIYNYEYKNSLLSDADIMEAVIFSNVQIEVL 987
            |.||.|.:.|:::..:   |..|.||...|           ::.||::.|.:.:.|.: ..::|.
  Rat   969 LTQKLTKNLEIMLKDK---KQKVHEVQGGV-----------QDYLLTNKDCIYSCIVA-FSLDVT 1018

  Fly   988 ---------FNTKWPHTAPDSLAQALNSLAVAFIDG-DAGIKVELEVLPFSTIHTLQLHLNIDGY 1042
                     ||.:..|.:|.||: .|:::...::.| ||.|.|..:..|...........:..|.
  Rat  1019 RKEKTFTFWFNNEAYHASPLSLS-ILDNIIFKYLSGPDATITVSNKPQPQPFTKGRSEERSASGI 1082

  Fly  1043 DLIF-----ASCLSFCFCFIWSIPLLHMTLS-RDGRYNYVELIAGMPTIVLIVAFLIYELLVVLL 1101
            .::|     .|..:..||.        ||:: |..:..:::.::|:.|:...::.|:::|::..:
  Rat  1083 QIVFNLLFGMSIFTSGFCL--------MTVTERVSKAKHIQFVSGVYTLNFWLSALLWDLIIHFV 1139

  Fly  1102 ALFPINIAVIFFHWDLLMDSNIHIYSVYVMFIIAACVFSLNILITIMPISDMPFVYL-------- 1158
            |.  :.:.::|.:.|      :||......|:      ...:::.:...|.:||:||
  Rat  1140 AC--VLLLLVFLYTD------VHILLENYNFL------DTMLILMLFGWSIIPFIYLLSFWYNNS 1190

  Fly  1159 -----KV-LLAYSLGILVYI--AVKELRPFTNPNTAHFLL--LDFHPFYALLHNLMRIASISEKI 1213
                 |: :..:.||.:..|  ||.||.|....:|.:.:|  |...|.|....::.:..||.|..
  Rat  1191 TNAYIKIFVFNHCLGFMSIIVDAVVELIPDIKTSTKNLILNSLLLLPIYNFGMSIFKYYSIQEIR 1255

  Fly  1214 WLCSDRQIYETSVYADQCNTIPNCCDD---------------DAQEFYHLRYLCCVYLLLVVVW- 1262
            .|||.         ....||...|..:               .|.....|.|...:.||....|
  Rat  1256 KLCSS---------LGSLNTFSGCQHELTVYSMDKRAIGRHVTAMAATGLIYFLFIILLETTSWN 1311

  Fly  1263 ----------ISIF-IFLKSHMVKRRPRQPKYFWDSDPDSKYDQNILHIMEPSELENTWIHEKSR 1316
                      ..|: ||.|:.|.|          :...||: |:::.:..| :.|:::|
  Rat  1312 LKAFIYRYVLFGIYKIFYKARMSK----------ELSGDSE-DEDVQNERE-TILQHSW------ 1358

  Fly  1317 VSTLERNHIESKALHVEHLSVFFGL--KAAIKHIDFMVNRYQVMSVFGANGTGKSVLLKTILGIY 1379
                  :.:.|..|..:.:.::|.:  ..|:::|...:.:.:...:.|.||.||:...|.:.|..
  Rat  1359 ------HSLNSTVLIKKLIKIYFKIPPTLAVRNISLTIQKEECFGLLGLNGAGKTTTFKILTGEE 1417

  Fly  1380 TPSSGRI------ISSKTVPFKSKDLDSCHMVGYSAQEFQTMQLMTILETWDLILRIRRSKQISF 1438
            ..:||.:      |:...:..:||       :||..|....:..||..|...:..|:....:.:.
  Rat  1418 IATSGDVFIEGYSITRNILKVRSK-------IGYCPQFDALLDYMTSREILTMYARVWGIPENNI 1475

  Fly  1439 RAEATKLCKIFGLYKYRFNSLSICSQGVLKRLSLGIALMSDAELILLDDPFTHLDIVSQRSMLHI 1503
            |:....|.|:..|.......:...|.|..:|||..||:|.::.::.||:|.|.:|.:::|.:.:.
  Rat  1476 RSYVNNLLKMLYLKPQAEKFIYTLSGGNKRRLSTAIAIMGNSSVVFLDEPSTGMDPLARRMLWNA 1540

  Fly  1504 IHDLRRRGHSIIYTCSDTAYSTPAL--RMATLSYPGIAVIGEREEMQQNYYSSYYMVETRIHLAE 1566
            :...|..|..||.| |.:.....||  |:|.:....:..:|..:.::..:.:.|.|
  Rat  1541 VIRTRESGKVIIIT-SHSMEECEALCTRLAIMVQGKLVCLGSPQHLKNKFGNIYTM--------- 1595

  Fly  1567 LGSPIDFDSQSTEAKEDRAGTTGTLLRHKHQEFSAAFTDSADRWKYLKLCGVIENVFPHAIIKNV 1631
               .|.|          :.||...:::                    .|...|..|||.:.:|..
  Rat  1596 ---NIKF----------KTGTDDDVVQ--------------------DLKNYIAEVFPGSDLKQE 1627

  Fly  1632 SFPRVCFWLSSHMYPMSRIVDTLHRNKQDF--YSFSVSQPSVNSVFLSIHRQKSNKDAF 1688
            :...:.:::.|......::...|.:.|:|:  ..:|:||.::..|||:.....:.:..:
  Rat  1628 NQGILNYYIPSKDNSWGKVFGILEKAKEDYNLEDYSISQITLEQVFLTFANPDNTESGY 1686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	135/512 (26%)
		ABC_subfamily_A	519..737	CDD:213230	69/220 (31%)
		P-loop_NTPase	1330..1517	CDD:422963	45/194 (23%)
Abca14	XP_038957098.1	rim_protein	<100..1681	CDD:130324	382/1756 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342181
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X215
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950