Protein Alignment CG43672 and ABCA

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: NP_608445.2
• Gene: ABCA / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Alignment Length: 1816
• Identity: 404/1816 - (22%)
• Similarity: 767/1816 - (42%)
• Gaps: 273/1816 - (15%)

  Fly     9 FCLLVWKNFQKQKHNKLVLILSLVLPVMSSLFLLFIRSSSDS---NMRDYSIR--AEAELLEFSW 68
            |.||:|||:..|.::|..:::.||||.:.||.|:.:|:..|:   .:|.|:.:  .:..||:.|.
  Fly    10 FVLLLWKNWTLQWNHKWQMVIELVLPAIFSLLLVLVRTLVDTEQKGVRYYNEQNLTDLNLLQHSL 74

  Fly    69 --SSLIGKI------QERRAKMASKQRNFTTNVFIPDIRVAFAPNSNAALRRLMGDALGKLSMSE 125
              ||.:||:      ..||     |...|:...||    :.::| .|..|::|:.:|.  .|:.:
  Fly    75 HRSSYLGKLIALIAPNRRR-----KNGGFSKFEFI----LCYSP-VNPVLKKLVEEAW--QSLGK 127

  Fly   126 DKIVDFENCNDMRIHAASEHYLASVCF----RNVDESLNGLPTVLNFAIIMPSELRN----YEDT 182
            :||.:.||...:.:...|::..|.|.|    .|:.|: :.||...:||:..|:|||.    ..:|
  Fly   128 NKICESENATQLELDTVSKNAFAGVQFDDAWANLTEN-DPLPNDFHFALRFPAELRTATIAIANT 191

  Fly   183 WIGDSWKETTTLMDRDVAEEDEFDEDG--YTDYMGEGFVPLQYHISMQFLRATASKVEKLPKVVM 245
            |:......|..|    ....:|.|:||  ...|:.|||:|||:.:||.:||..:.: :.||.|||
  Fly   192 WLTMRLFPTIDL----TGPRNEGDDDGGIPPGYLREGFLPLQHSLSMAYLRQKSGE-QDLPNVVM 251

  Fly   246 RRFNENPNVL--LSEGIGTSVVLLILLGFMFPVTILTTLIVEERELGQRYMLKILNASATLQMAA 308
            :|:.....:.  |.||:.:.:.|:|||.|::|.|.:|..|..|:|...:.::||:..|..|...|
  Fly   252 KRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYITAEKEKQLKEVMKIMGLSNWLHWTA 316

  Fly   309 WFFNVFTHFLITSLLITILLKIEWNGATAAVNKCPWPILLCFLISYGCSVTSLIILMTSAMRRSR 373
            ||...|....|:::||.||:||.|:...|.:....:..|:.|||.|..|......:|.:...|:.
  Fly   317 WFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALVFFLIIYIVSSICFCFMMATFFSRAS 381

  Fly   374 VAMVMAPIIWILLALPL-----------LSKKELLSDGPDVFYGFATVLLCNVSFSRGLSKIFYI 427
            .|..:..:||.:..:|.           ||.|          .|::  |:.|.:...|:..|...
  Fly   382 TAAAVTGLIWFIAYIPYSFTINSYDDLSLSSK----------LGWS--LISNTAMGFGIKLILGF 434

  Fly   428 E-----------------DYTLGVTIGKYMFYRVSKSDFGIFVPIVCFYVQTI----FCTLLAMI 471
            |                 |.||  |:|..|...:...   :...|:|.||:.:    |.......
  Fly   435 EGTGEGLQWSNFFTPVSVDDTL--TLGAVMIMMLVSC---VIYMIICLYVEQVMPGSFGVPRPWN 494

  Fly   472 FENNAYFWLAIRVKNLLKKYHATRSAV-GRLKRQIPEVSFSKTSAEAL-IEFRGVWQKYSNSTYV 534
            |.....||...|      :|....... |.::::.|:...::...:.: ::.|.:.:::.|. .|
  Fly   495 FPFTREFWCGER------EYTGVEDIPNGHVEQRDPKAFETEPEGKHIGLQMRHLKKRFGNK-MV 552

  Fly   535 VQDITLNVYAGEVVALLGHNASGKSTIIKMLYGRTRPKLGEIYLSGFNIVTQRKEALKNSSISMS 599
            |:.:::|::..|:..|||||.:||:|.|.||.|...|..|...::|.:|.|..:.|..:..|...
  Fly   553 VKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTAIINGSDIRTNIEGARMSLGICPQ 617

  Fly   600 YKTLFTELVVLDHLVFLSRLRGLSKTEAKLEAKALLRYLKLEDWEKTLVNDLTIGQRRVLQFLCA 664
            :..||.|:.|.:|:.|.||::||.....:.|....|:.::|||......:.|:.|.:|.|...||
  Fly   618 HNVLFDEMSVSNHIRFFSRMKGLRGKAVEQEVAKYLKMIELEDKANVASSKLSGGMKRKLSVCCA 682

  Fly   665 FAGGNQIVILDKPFDGIDEQRTSLFYSLILDQKKNRSIFFTSNNQKVASGIADRIFVLSKGKLQA 729
            ..|..::|:.|:|..|:|.......:.|:..:|..|::..|::....|..:.|||.::..|:|:.
  Fly   683 LCGDTKVVLCDEPSSGMDPSARRQLWDLLQQEKVGRTLLLTTHFMDEADVLGDRIAIMCDGELKC 747

  Fly   730 FGTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFMATFIPEIEMDSILADCASFLVKHKYHTELIN 794
            .||...|.:.....||||....:.|...:|.|.:..:||.::.:..:....|:.:......:...
  Fly   748 QGTSFFLKKQYGSGYRLICVKRDDCETNEVTALLNKYIPGLKPECDIGAELSYQLPDSASAKFEE 812

  Fly   795 LIENLARLKNDLNVYSFEIHECSIDDILASL--------YTRDKSTLEFGQPGL------QTLLA 845
            :...|....::|::..:.:...|::::...:        ..:|:..:..|..|.      :::.:
  Fly   813 MFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAEKDNTGNIKDQHEIMNGGSGFRGEDDNESVQS 877

  Fly   846 SRQQSAKRRFIIPTMYLLEELRQLLIA----DTRNWFLPILKLTLPSLVVVWTLSMPYFWHNCRQ 906
            ....|..||.:.....|..:.:.:|:.    ..||..|.:::..:|...||.|:.:.......::
  Fly   878 DGIFSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNKLLLLIQNIMPVFFVVVTILIIKTQGTFQE 942

  Fly   907 PGHITFPMSDHGDGIILMQKDTLDS----------ELLVAS-------EMYAKVG----VTEVDK 950
            ...||..::.:...:.::.:..:.:          |.|..|       |:....|    :.::.|
  Fly   943 LKPITISLTQYPLAVTVLDRSNVQNGTGYEIANKYEDLARSYGSNYGLELTGTQGFEDYILDLGK 1007

  Fly   951 TVDITTFIYNYEYKNSLLSDADIMEAVIFSNVQIEVLFNTKWPHTAPDSLAQALNSLAVAFIDGD 1015
            |:.:.   .|..|    |..|.|.|:      :|....|.:..||||.::....|::|.......
  Fly  1008 TIQVR---INSRY----LVAATITES------KITAWLNNQALHTAPLTVNMVHNAIADKLFGSS 1059

  Fly  1016 AGIKVELEVLPFSTIHTLQLHLNIDGYDL--IFASCLSFCFCFIWSIPLLHMTLSRDGRYNYVEL 1078
            ..|:|....||::| .||...|: .|.:|  ..||.|.||.||:.||.:|.:...|:.|...::.
  Fly  1060 VKIQVTNAPLPYTT-STLLSQLS-TGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQF 1122

  Fly  1079 IAGMPTIVLIVAFLIYELLVVLLALFPINIAVIFFHWDLLMDSNIHIYSVYVMFIIAACVFSLNI 1143
            :.|:......::..|.:....::....:.|.::.|     .::.:..:.....:.:...:|...:
  Fly  1123 VGGVKVWTFWLSQFICDFASYIVTALIVVITIVCF-----QETGLSTFGELGRYYLLLLLFGFAV 1182

  Fly  1144 LITIMPISDMPFVYL------------------KVLLAYSLGILVYIAVKELRPFTNPNTAHFL- 1189
            |         ||:|:                  .:....:|.|:|.:...||  |...:||..|
  Fly  1183 L---------PFIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSEL--FDTKDTADILG 1236

  Fly  1190 -LLDFHPFYALLHNLMRIASISEKIWLCSDRQIYETSVYADQCNTIPNCCD----------DDAQ 1243
             :....|.::|..:|.::.:.:.....|:........:.   |..:|.||:          ....
  Fly  1237 WIFRIFPHFSLAMSLNKVYTNTATRNACAKAGALPPILL---CELVPQCCNLKPYFAWEEPGVLP 1298

  Fly  1244 EFYHLRYLCCVYLLLVVV----WISIFIFLKSHMVKRRPRQPKYFWDSDPDSKYDQNILHIMEPS 1304
            |..::.....|:.|:::|    .|:..:|....::.:.|..|                    ...
  Fly  1299 ETVYMAVTGVVFFLIIIVLEFRLINELMFKIRQLISKPPPPP--------------------TEG 1343

  Fly  1305 ELENTWIHEKSRVSTLERNHIESKALHVEHLSVFFGLKAAIKHIDFMVNRYQVMSVFGANGTGKS 1369
            :|::...:|:.|:..:..|.:.:|.|.::.::.::|...|:..:...|...:...:.|.||.||:
  Fly  1344 QLDDDVANERERILQMSSNELATKNLVLDRVTKYYGQFMAVNQVSLCVQEVECFGLLGVNGAGKT 1408

  Fly  1370 VLLKTILGIYTPSSG-RIISSKTVPFKSKDLDSCH-MVGYSAQEFQTMQLMTILETWDLILRIRR 1432
            ...|.:.|....||| ..:...::   ..:::|.: |:||..|....:..:|..|...:...:|.
  Fly  1409 TTFKMMTGDERISSGAAYVQGLSL---ESNMNSIYKMIGYCPQFDALLDDLTGREVLRIFCMLRG 1470

  Fly  1433 SKQISFRAEATKLCKIFGLYKYRFNSLSICSQGVLKRLSLGIALMSDAELILLDDPFTHLDIVSQ 1497
            .::...|..:..|.|.||..|:........|.|..::||..||::....:|.||:|.|.:|..::
  Fly  1471 VQESRIRQLSEDLAKSFGFMKHIDKQTHAYSGGNKRKLSTAIAVIGSPSVIYLDEPTTGMDPAAR 1535

  Fly  1498 RSMLHIIHDLRRRGHSIIYTCSDTAYSTPAL--RMATLSYPGIAVIGEREEMQQNYYSSYYM-VE 1559
            |.:.:::..:|..|.||:.| |.:.....||  |:|.:.......||..:.::..:.....: ::
  Fly  1536 RQLWNMVCRIRDSGKSIVLT-SHSMEECEALCTRLAIMVNGEFKCIGSTQHLKNKFSKGLILKIK 1599

  Fly  1560 TRIHLAEL-------GSPIDFDSQSTEAKEDRAGTTGTLLRHKHQEFSAAFTDSADRWKYLKLCG 1617
            .|.:|..|       |...:.|.|:..|:..:......      :||
  Fly  1600 VRRNLEALRQARLSGGYARNPDEQTVPAQMSQRDIDAV------KEF------------------ 1640

  Fly  1618 VIENVFPHAIIKNVSFPRVCFWLSSHMYPMSRIVDTLHRNKQ--DFYSFSVSQPSVNSVFL 1676
             :|..:|::|::......:.|::.......|||...:..|:.  :...:||||.::..:||
  Fly  1641 -VETEYPNSILQEEYQGILTFYIPLTGVKWSRIFGLMESNRDQLNVEDYSVSQTTLEEIFL 1700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	129/499 (26%)
		ABC_subfamily_A	519..737	CDD:213230	64/217 (29%)
		P-loop_NTPase	1330..1517	CDD:422963	45/188 (24%)
ABCA	NP_608445.2	ABC2_membrane_4	254..434	CDD:289500	51/191 (27%)
		ABC2_membrane_3	<269..475	CDD:289468	55/222 (25%)
		CcmA	538..843	CDD:224054	78/305 (26%)
		ABC_subfamily_A	538..755	CDD:213230	64/217 (29%)
		ABC2_membrane_3	913..1316	CDD:289468	79/436 (18%)
		ABC_subfamily_A	1369..1587	CDD:213230	53/221 (24%)
		drrA	1376..1702	CDD:130256	75/354 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451215
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	6	5.950