Protein Alignment CG43672 and CG1494

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: NP_001259763.1
• Gene: CG1494 / 33102
• FlyBaseID: FBgn0031169
• Length: 1695
• Species: Drosophila melanogaster
• Alignment Length: 1868
• Identity: 433/1868 - (23%)
• Similarity: 758/1868 - (40%)
• Gaps: 399/1868 - (21%)

  Fly     9 FCLLVWKNFQKQKHNKLVLILSLVLPVMSSLFLLFIRSSSDSNMRDYSIRAEAELLEFSWSSLIG 73
            |.|:.|||.:.|..|.|.|::.|::|.:.:|..:.:|.....|.|..::....: |:.||..::.
  Fly    10 FLLMNWKNHKLQLANPLELLVILLVPPLFTLVAVLMRFFIPVNHRSDTVYDPID-LDRSWMQMVE 73

  Fly    74 KIQERRAKMASKQRNFTTNVFIPDIRVAFAPNS----NAALRRLMGDALGKLSMSEDKIVDFENC 134
            |::  :|:..:...|...|.|.|.:.:.:||..    .|.:||:........|      |.||:|
  Fly    74 KLE--KARQVADTYNVKGNPFTPHLVIGWAPKRYGIFQAMMRRVQKQIEPMTS------VGFEDC 130

  Fly   135 NDMRIHAASEHYLASVCF------------RNVDESLNGLPTVLNFAIIMPSELRNYEDTWIGDS 187
            .:||.........|.:||            .:..||.:.:..:||:.|::|||||..:..:...:
  Fly   131 EEMRESVIENGLFAGLCFDGSPFVEDQVFEEDTLESYSNIQPMLNYTILLPSELRMLDGDFRMAN 195

  Fly   188 WKETTTLMDRD-----VAEEDEFDEDGYTDYMGEGFVPLQYHISMQFLRATASKVEKLPKVVMRR 247
            |   .||.:.|     :...::..|.|:..|:.|||:.||..:|..||..|:.|  .||.:.:||
  Fly   196 W---MTLYNDDPNTFVLTRLNQPYEGGFVGYVREGFIRLQKSVSESFLVLTSHK--SLPTIQIRR 255

  Fly   248 F-----NENPNVLLSEGIGTSVVLLILLGFMFPVTILTTLIVEERELGQRYMLKILNASATLQMA 307
            |     .::|   |...:...:..:|::||:||..:....:|.|::...|..|..:|....:...
  Fly   256 FPITGREQDP---LMGNLNYGMPFIIIIGFLFPAQLFVWQVVSEKQSQVRQFLINMNIGNLIHFV 317

  Fly   308 AWFFNVFTHFLITSLLITILLKIEWNGATAAVNKCPWPILLCFLISYGCSVTSLIILMTSAMRRS 372
            :|:.....:.:|:||:|..||||.|:.....:.:.||.||:..|..|.|:..:..|::.:..|.:
  Fly   318 SWYLKGLIYEMISSLIIAALLKIRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRNA 382

  Fly   373 RVAMVMAPIIWILLALPLLSKKELLSDGPD--------VFYGFATVLLCNVSFSRGLSKIFYIED 429
            ..|:.:..|:||:..:|..    :||:..:        |.|....|:..       |...|.||.
  Fly   383 LNAVRVLTILWIMSYVPTF----ILSNNLEGNIHALRYVSYALPNVVAT-------LVIEFLIER 436

  Fly   430 YTLGVTIGKYMFYRVSKSDFGIFVPIVCFYVQTIFCTLLAMIFENNAYFWLAI-----------R 483
            .::.....:...||::.....|.|            |..:.||..||..:.||           |
  Fly   437 ESIVHITWEDSGYRLNYDGGHITV------------TASSWIFMLNALVYCAIGLYVDMWRGGDR 489

  Fly   484 VKNLLKK-----------YHA-------TRSAVGRLKRQIPEVSFSKTSAEALIEFRGVWQKY-S 529
            ....:||           ||.       ...|:|....:|.||..|....:  ::.:.:.::: :
  Fly   490 SGKKMKKPNTNASVQEDPYHERGDSFTHQGQAIGVNSTKIYEVEPSHRRFK--LKIKKLCKRFAT 552

  Fly   530 NSTYVVQDITLNVYAGEVVALLGHNASGKSTIIKMLYGRTRPKLGEIYLSGFNIVTQRKEALKNS 594
            |....:...:.|||..||..|:|||..||||::|:|.|...|..|.:.:|..||.|:||.|....
  Fly   553 NDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHNIQTERKAASMEL 617

  Fly   595 SISMSYKTLFTELVVLDHLVFLSRLRGL-SKTEAKLEAKALLRYLKLEDWEKTLVNDLTIGQRRV 658
            .|:..:..|.|...|:|:|.|:.|::|| :..|...::...|..|::...:...:..||.....:
  Fly   618 GIAFGHDMLLTGFTVIDYLRFICRVKGLHNNIEIDGQSNYFLNVLQIGGLKTKRIRTLTDRDLCL 682

  Fly   659 LQFLCAFAGGNQIVILDKPFDGIDEQRTSLFYSLILDQKKNRSIFFTSNNQKVASGIADRIFVLS 723
            :...|||.|.:.|:::|.....:|::..||.::||.::|..|:|...||:..:|..||||:.::|
  Fly   683 VSICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEEKSKRTIILVSNSPALAENIADRMAIMS 747

  Fly   724 KGKLQAFGTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFMATFIPEIEMDSILADCASFLVKHKY 788
            .|:|:..||...|..|....|||.....:.....:::..|.:::|.:.::..:....:|::::|:
  Fly   748 NGELKCTGTKPFLKNMYGHGYRLTCVKGKNYKRDELFGMMNSYMPNMSIERDIGYKVTFVLENKF 812

  Fly   789 HTELINLIENLARLKNDLNVYSFEIHECSIDDILASLYTRDKSTLEFG-----QPG--------- 839
            ..:...||::|......|.|.||.|.:.|:::|.          |.||     |.|
  Fly   813 EDQFPMLIDDLEENMQQLGVVSFRIRDTSMEEIF----------LRFGCEDNDQSGAFQSHENAQ 867

  Fly   840 ------LQTLLASRQQSAKRRFIIPTMYLLEELRQLLIADTRNWFLPILKLTLPSLVVVWTLSMP 898
                  ..||..:.::..:..:.:..::....:.:..||..|:|.:.|.::...:||.|.|.|..
  Fly   868 VLLEEYYSTLAEANEKGRRTGWKLFFLHGRAVIYKRWIAAHRHWIVLIFEVLAMALVAVCTFSSI 932

  Fly   899 YFWHNCRQPGHITFPMSDHGDGIILMQKDTLDSELLVASE------MYAKVGVTEVDKTVD--IT 955
            :.:....:...:||.:|         |..|:|:.:.:.||      |:|.  .||:....|  :.
  Fly   933 FIYGKNYELEPLTFNLS---------QLHTVDAFVELFSEEEDVKDMHAY--YTELLYWYDAHVA 986

  Fly   956 TFIYNYEYKNSLLSDADIMEAV--------IFSNVQIEVLFNTKWPHTAPDSLAQALNSLAVAFI 1012
            |...|.....:||:.......|        .|....:...||....|:||.:|....|::|....
  Fly   987 TLTKNRHNAYALLTQNQFTAHVNSRYIFGATFDQKIVTAWFNNIPLHSAPYALNVVHNAVARHLF 1051

  Fly  1013 DGDAGIKVELEVLPFSTI--------HTLQLHLNIDGYDLIFASCLSFCFC----FIWSIPLLHM 1065
            |.:|.|.|.|..|||.|.        ||             |..||:|..|    |||....::|
  Fly  1052 DEEATIDVTLAPLPFRTAINTFPPSSHT-------------FGGCLAFGICFVLTFIWPAFAIYM 1103

  Fly  1066 TLSRDGRYNYVELIAGMPTIVLIVAFLIYELLVVLLALFPINIAVIFFHWDLLMDSNIHIYSVYV 1130
            ...|.......:.:||:.........::|:||.:|
  Fly  1104 ITERGSLLKKQQFLAGVRVCSYWTFTVLYDLLFLL------------------------------ 1138

  Fly  1131 MFIIAACVFSLNILITIM--PISD-MPFVYLKV----------LLAY------------------ 1164
              |..|||.   :::.:.  |..| |.:.|:.|          ||||
  Fly  1139 --IFCACVV---VMVALYENPNHDVMLYGYISVTLMLGGFWVILLAYLMASLCRNPCYGFLWLCG 1198

  Fly  1165 --SLGILVYIAVKELRPFTNPNTAHFLLLD--FHPFYALLHNLMRIASISEKIWLCSDRQIYETS 1225
              |:|::.:.....    |:|.:   :||:  |...|.:...:.::..|.|...:|.|..:..||
  Fly  1199 INSIGLVCFSQFYR----THPES---MLLEPTFMAMYTVATVICKLFMIYEFKLICMDPVVNFTS 1256

  Fly  1226 VYADQCNTIPNCCDDD-----AQEFYH---------LRYLCCVYLLLVVVWISIFIFLKSHMVKR 1276
            |...:||:|||||...     ....||         :..|.|   |.|..:.||..|....:..|
  Fly  1257 VEVFKCNSIPNCCIKSNYGTFTAGIYHDLVILTLLDIILLAC---LFVSEYHSILGFADCRLDTR 1318

  Fly  1277 RPRQPKYFWDSDPDSKYDQNILHIMEPS--ELENTWIHEKSRVSTLERNHIESKALHVEHLSVFF 1339
            ....|    ||:.:|:....||.....:  :.|:|     ||::..||:         ::.:|..
  Fly  1319 TNESP----DSNQESRAFPGILSNDTAALVDKEHT-----SRLNEEERS---------KYAAVGI 1365

  Fly  1340 GL------KAAIKHIDFMVNRYQVMSVFGANGTGKSVLLKTILGIYTPSSGRI------ISSKTV 1392
            |:      ...::.:||.:.:.:.:|:.|||.:||:.|||.::.....::|::      :::..|
  Fly  1366 GIVSKYRRNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWIHDYSVNTHRV 1430

  Fly  1393 PFKSKDLDSCH-MVGYSAQ------EFQTMQLMTILETWDLIL---RIRRSKQISFRAEATKLCK 1447
                    .|: ||||..|      ||...:|:.|    ..:|   |.|..:::|   ||  |.:
  Fly  1431 --------QCYRMVGYCPQKDSLPSEFTPRELLYI----HAMLQGHRHRIGRELS---EA--LLR 1478

  Fly  1448 IFGLYKYRFNSLSICSQGVLKRLSLGIALMSDAELILLDDPFTHLDIVSQRSMLHIIHDLRRRGH 1512
            :.||......|:.:|:.|.::||....|::...:||.:|.....||...:|.:|.:...::..|.
  Fly  1479 LVGLTPCWNRSVRMCTTGQIRRLYFAYAVLGSPDLICVDGVPAGLDPTGKRIILMMTSTMQAMGS 1543

  Fly  1513 SIIYTCSDTAYSTPALRMAT-LSYPG-IAVIGEREEMQQNYYSSYYMVETRIHLAELGSPIDFDS 1575
            |.:||.. |......|.:.| |...| :.:|...:...:||.|. |.:|.|.            .
  Fly  1544 SFLYTML-TGLDAERLSLRTPLLLEGQLWMIRPMDTETENYKSG-YQLEVRF------------K 1594

  Fly  1576 QSTEAKEDRAGTTGTLLRHKHQEFSAAFTDSADRWKYLKLCGVIENVFPHAIIKNVSFPRVCFWL 1640
            :........:..|..|:.|        |..|.::    |....:|..||.|::
  Fly  1595 RKVNPNVSMSRATWNLINH--------FPMSPNK----KFSAFMEIKFPDAVL------------ 1635

  Fly  1641 SSHMYPMSRIVDTLHRNKQDFYSFSVSQPSVNSVFLSIHRQKSNKDAF 1688
                        |:.|:....:...:...:.:.:||::     .||||
  Fly  1636 ------------TIERDDSMVFVLPLGTTTFSEIFLTL-----RKDAF 1666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	130/504 (26%)
		ABC_subfamily_A	519..737	CDD:213230	67/219 (31%)
		P-loop_NTPase	1330..1517	CDD:422963	49/208 (24%)
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	56/242 (23%)
		CcmA	541..848	CDD:224054	86/316 (27%)
		ABC_subfamily_A	541..761	CDD:213230	67/219 (31%)
		ABC2_membrane_3	911..>1189	CDD:289468	74/336 (22%)
		ABC2_membrane	<1080..>1188	CDD:304374	29/142 (20%)
		ABC_subfamily_A	1370..1577	CDD:213230	55/224 (25%)
		PRK14255	1371..1586	CDD:172743	57/232 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451213
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	6	5.950