Protein Alignment CG43672 and CG34120

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: NP_001285513.1
• Gene: CG34120 / 318066
• FlyBaseID: FBgn0083956
• Length: 1998
• Species: Drosophila melanogaster
• Alignment Length: 1533
• Identity: 290/1533 - (18%)
• Similarity: 581/1533 - (37%)
• Gaps: 309/1533 - (20%)

  Fly   141 AASEHYLASVCFRNVDESLNGLPTVLNFAIIMPSELR-NYEDTWI-GDSWKETTTLMDRDVAEED 203
            :||:|...::.    ..||:|:.|         .|:| ..|.|.: ||  .:...|.:.||.:..
  Fly   528 SASDHEATTIS----PSSLDGVTT---------EEVRVTTEQTVVSGD--PDLLLLKNEDVLKRS 577

  Fly   204 E----FDEDGYTDYMGEGFVPLQYHI-SMQFLRATASKVEKLPKVVMRRFNENPNVLLSEGIGTS 263
            :    ||..|.....|:.....::.: :|||.    :|....|..:...|..  .:.|::|
  Fly   578 KRQGLFDLLGGFGGSGDANKKNKFEVDNMQFY----TKQFPYPAFLNDVFKR--GLYLAQG---- 632

  Fly   264 VVLLILLGFMFPVTILTTLIVEE----RELGQRYMLKILNASATLQMAAWFFNVFTHFLITSLLI 324
            |.:..|||    :.:...|.|.|    ||.....:::.:...|..::.||....|....:...||
  Fly   633 VQVAYLLG----LVVFVALSVRERIWMRESRNSMLMRSMGLKAHSELVAWALMSFLELCVIFALI 693

  Fly   325 TILLKIEWNGATAAVNKCPWPILLCFLISYGCSVTSLIILMTSAMRRSRVAMVMAPIIWILLALP 389
            :.:|   ::|.......  |..::.:.:|:|..:.|...:.|:....:.:..|.:.:::.:...|
  Fly   694 SGVL---YSGGILGYTN--WFFMMFYCLSFGLCLISFCYMCTNFFNSANIGAVASALLFFISLCP 753

  Fly   390 LLSKKELLSDGP-DVFYGFATVLLCNVSFSRGLSKIFYIEDYTLGVTIGKYMFYRVSKSDFGIFV 453
            .:.  .|:.|.. .||..|...|....:|::|..::..:|....|:|:...:....::|:..  :
  Fly   754 FII--VLMFDAKLSVFESFLVDLSFTTAFAKGWGELIRMELQQEGLTVRHLIQVGPARSECA--M 814

  Fly   454 PIVCFYVQTIFCTLLAMIFE----NNAYFWLAIRVKNLLKKYHATRSAV-GRLKRQIPEVSFSKT 513
            .::.|.:..:...::.:.::    .:.|.::.:           :||.: |:|...:..||
  Fly   815 ALLMFLLDLLLYAVIGLAYQRYKKTDNYSFVKV-----------SRSQLDGKLGASLVNVS---- 864

  Fly   514 SAEALIEFRGVWQKYSNSTYVVQDITLNVYAGEVVALLGHNASGKSTIIKMLYGRTRPKLGEIYL 578
                         |...|...|.:::|:....:|..|||.|.:||||:||:|.|:.|...|::.|
  Fly   865 -------------KLYGSKCAVSNLSLDFARNQVSCLLGRNGAGKSTLIKLLTGQIRQSSGKVLL 916

  Fly   579 SGFNIVTQRKEALKNSSISMSYKTLFTELVVLDHLVFLSRLR-------GLSKTEAKLEAKALLR 636
            :|.:.|          .:......|...|...:||...::::       |:.  |.:.|....|:
  Fly   917 AGEHQV----------GVCWQDNILIPTLTAREHLQLYAQIKIPPGGSGGVE--EIRSEVAQTLQ 969

  Fly   637 YLKLEDWEKTLVNDLTIGQRRVLQFLCAFAGGNQIVILDKPFDGIDEQRTSLFYSLILDQKKNRS 701
            .|.....|......|:.|.||.|....||.....:||||:|.:|:|.:.....:.||...::.|:
  Fly   970 SLNFGKHESYPSWQLSGGYRRRLCVAIAFIASPSVVILDEPCNGVDAKARKDIWQLIERLRQGRA 1034

  Fly   702 IFFTSNNQKVASGIADRIFVLSKGKLQAFGTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFM--- 763
            :.|.::....|..::|.:.::..|::.|..:...|.|:...:|.:.:    :|:......|:
  Fly  1035 VIFATHFMDEAKYLSDSLVIMRNGRIIAQHSRDSLQRLCTSNYSIRL----RCADATGVTFVIQK 1095

  Fly   764 -ATFIPEIEM-DSILADCASFLVKHKYHTELI--NLIENLARLKNDLNVYSFEIHECSIDDILAS 824
             ...:|:.:: .|..||....|..:..:.|.:  ..:|.|..|::.:...|....|.:....|..
  Fly  1096 AQQLLPQTQVTHSGAADYPHSLTINASYAEHLTPGAVEFLELLQSQVTAGSISDVELTTSSSLEQ 1160

  Fly   825 LYTR---------------DKSTLEFGQPGLQTLLASRQQSAKRRFIIPTMYLLEELRQLLIADT 874
            .:.:               |:|.:..|    ..::.....:|.::|   .:.:.:.||.|    :
  Fly  1161 EFEQLNRNGEDAGPRRPASDRSGVVAG----PAMITDEPPTACKQF---RLLMGKRLRHL----S 1214

  Fly   875 RNWFLPILKLTLPS---LVVVWTLSMPYFWHNCRQPGHITFPMSDHGDGIILMQKDTLDSELLVA 936
            ||:.|.:..|.||:   |..:|.:|                          ...:|..|:.|.::
  Fly  1215 RNYRLLLYVLLLPALFELCAMWFVS--------------------------YRLEDDFDTVLPLS 1253

  Fly   937 SEMYAKVG-VTEVDKTVDITTFIYNYEYKNSLLSDAD-IMEAVIFSNVQ---------------- 983
            ..:|.:.. ....::....:..:|     ..|.:..| :.|..:|:..|
  Fly  1254 RSLYPQTAQFLSHERATSFSEKLY-----PQLRTSCDHLGECRVFNTSQQSYDWVLNSWGEYSER 1313

  Fly   984 -----------IEVLFNTKWPHTAPDSLAQALNS--LAVAFIDGDAGIKV--ELEVLPFSTIHTL 1033
                       ..|.:|.|..|:....| ..|||  |.....|.::.|..  |...|.|:.:.|.
  Fly  1314 RYGGYGLNGSGATVWYNNKGYHSMMAWL-NDLNSELLRTTMNDSESSILTLNEPWKLGFAELSTS 1377

  Fly  1034 QLHLNIDGYDLIFASCLSFCFCFIWSIPLLHMTLSRDGRYNYVELIAGMPTIVLIVAFLIYELLV 1098
            .:........::|  .|...|..:.:...:::...|.......:.:.|:..:...:..|:::.||
  Fly  1378 SILRQAGDGSMVF--ILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLV 1440

  Fly  1099 VLLALFPINIAVIFFHWDLLMDSN--IHIYSVYVMFIIAACVFSLNILITIMPISDMPFVYLKVL 1161
            ::|.|....:.::.|...:.:|..  :.|..:.:.|.. |||.|:::...|  .||.....:.:.
  Fly  1441 MVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSF-ACVPSVHVAEKI--FSDSSIAIVSIF 1502

  Fly  1162 LA------YSLGILVYIAVKELRPFTNP-----NTAHFLLLDFHP----FYALLHNLMRIASISE 1211
            .|      .::||::.:.|....|..:.     |.| ||:...|.    |..|..|.| :|.:..
  Fly  1503 CANLIVPLVTMGIILILGVVGDGPAWDDWRHALNQA-FLIFPIHALGDGFLELCKNYM-VALVFR 1565

  Fly  1212 KIWLCSDRQIYETSVYADQCNTIPNCCDDDAQEFYHLRYLCCVYLLLVVVWISIFIFLKSHMVKR 1276
            :         |:...|..     |...|...:.|..|       ||:.|..:.|.:.::.|:::|
  Fly  1566 R---------YDIDSYKH-----PLASDLLGRHFTAL-------LLVGVAALIINVLIEWHLLRR 1609

  Fly  1277 RPRQPKYFWDSDPDSKYDQNILHIMEPSELENTWIHEKSRVSTLERNHIES---------KALHV 1332
                   .|         |.:..:     |:.|:..|..::..|:..:|:|         :|:..
  Fly  1610 -------LW---------QRVERL-----LDCTYRRELDKLGQLKLVNIQSIFKSCVDTGEAVRA 1653

  Fly  1333 EHLSVFFGL-KAAIKHIDFMVNRYQVMSVFGANGTGKSVLLKTILGIYTPSSGRIISSKTVPFKS 1396
            |:|.:.:.. ..|:::::|.|.|.:...:.|.||.|||.:.|.:.|...|..|:|.      |:.
  Fly  1654 ENLWLAYRRGHYAVRNVNFSVQRGECFGLLGKNGAGKSTIFKLLTGQLQPDVGQIY------FEQ 1712

  Fly  1397 KDLDSCHMVGYSAQEFQTMQLMTILETWDLI-----LR-IRRSKQISFRAEATKLCKIFGLYKYR 1455
            ..:..|.         |:..|..:|.|.:.|     || ||...|...|...|     :.|..|:
  Fly  1713 PGISYCP---------QSNPLDPLLTTTECIRFYGRLRGIRDLDQFLDRVLDT-----YELRPYK 1763

  Fly  1456 FNSLSICSQGVLKRLSLGIALMSDAELILLDDPFTHLDIVSQRSMLHIIHDLRRRGHSIIYTCSD 1520
            ...:...|.|..::|::.:........:|:|:|.:.:|.|::..:...|..|.....:::.|...
  Fly  1764 DVQVRNLSGGNRRKLTVAVTCCGCTPTVLMDEPTSDMDPVTRDMVYATIEQLLLARRAVVLTSHS 1828

  Fly  1521 TAYSTPALRMATLSYPGIAVIGEREEMQQNYYSSYYMV 1558
            .:......:...:...|..:..:..:..::.:..||.|
  Fly  1829 VSEIEHLCQRVAVLRAGQVIASDSPQRLKSEHGGYYAV 1866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	97/482 (20%)
		ABC_subfamily_A	519..737	CDD:213230	54/224 (24%)
		P-loop_NTPase	1330..1517	CDD:422963	43/193 (22%)
CG34120	NP_001285513.1	ABC2_membrane_3	<621..760	CDD:289468	28/155 (18%)
		ABC_subfamily_A	859..1073	CDD:213230	58/242 (24%)
		drrA	865..1162	CDD:130256	71/312 (23%)
		ABC2_membrane_3	1230..1601	CDD:289468	74/430 (17%)
		Mem_trans	1436..>1552	CDD:304621	25/119 (21%)
		ABC_subfamily_A	1651..1857	CDD:213230	45/225 (20%)
		drrA	1666..1945	CDD:130256	46/221 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950