Protein Alignment CG43672 and abt-1

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: NP_001293854.1
• Gene: abt-1 / 182849
• WormBaseID: WBGene00000019
• Length: 1558
• Species: Caenorhabditis elegans
• Alignment Length: 1508
• Identity: 276/1508 - (18%)
• Similarity: 534/1508 - (35%)
• Gaps: 457/1508 - (30%)

  Fly   239 KLPKVVMRRFNENPNVLLSEGIGTSVVLLILLGFMFPV-TILTTLIVEERELGQRYMLKILNASA 302
            :|..|.::....:|..|..:   :.:.||.:|  :.|: :.|..|...:|..|...|...|:|..
 Worm   201 QLSNVYVKHSGNDPMFLKRQ---SDLFLLWIL--LLPICSRLIDLWNNDRSSGYYNMFLSLHARR 260

  Fly   303 TLQMAAWFFNVFTHFLITSLLITILLKIEWNGATAAVNKCPWPILLC-----FLISYGCSVTSLI 362
            .....|.|...:...||.||::.|            ||....|.:.|     |::.|...:.|..
 Worm   261 FHYFIAKFVFWYGIALIISLIVFI------------VNVLVVPAVFCSTYLQFVVCYAACIISFA 313

  Fly   363 ILMTSAMRRSRVAMVMAPIIWILLALPLLSKKELLSDGPDVFYGFATVLLCNVSFSRGLSKIFYI 427
            |.:.:....|                ||.:|          ..||    |..|:...|...:::
 Worm   314 IFLATTFPGS----------------PLFAK----------IVGF----LSMVAGEFGFGTVYH- 347

  Fly   428 EDYTLGVTIGKYMFYRVSKSDF-GIFVPIVC---------------FYVQTIFCTL----LAMIF 472
                 |:...:.......||:| |.::..||               .|..|.||..    ||..|
 Worm   348 -----GIGFFQLCVRHFGKSEFDGPWIDAVCTLCMTGNCVLLITVSIYFDTYFCLFTMEPLAFYF 407

  Fly   473 ENNAYFWL---------AIRVKNLL-----------KKYH----ATRSAVGRLKRQIPEVSFSKT 513
            .....:|:         ...||.::           ||.|    ..:::.|  .:.||.....|
 Worm   408 PLEKDYWMPEARSPQLDTFFVKQIILLKPGRSEITVKKAHDEILPAKTSTG--SKYIPPTPIVK- 469

  Fly   514 SAEALIEFRGVWQKYSNSTYVVQDITLNVYAGEVVALLGHNASGKSTIIKMLYGRTRPKLGEIYL 578
             ...|:...|:.::..|. :.|:.::|.|:.||||.|.||:..|...|:.::.|:.:|:.||:.:
 Worm   470 -GVPLVVLYGICKRIENH-WRVKQVSLTVHLGEVVTLYGHHGCGSGEILSIIAGQMKPEYGEVMM 532

  Fly   579 SGFNIVTQRKEAL-KNSSI-SMSYKTLFTELVVLDHLVFLSRLRGLSKTEAKLEAKALLRYLKLE 641
            .    .:||...: |.:.: :::|      |.|:.:|..:|::||:|.:.:.::  .:|..|.|.
 Worm   533 E----QSQRPLMISKTTDVPNVNY------LNVIQYLRLISKMRGVSASTSHID--EMLEELDLI 585

  Fly   642 DWEKTLVNDLTIGQRRVLQFLCAFAGGNQIVILDKP-FDGIDEQRTSLFYSLILDQKKNRSIFFT 705
            ..:...::.|:..|:..|:....|.|...:|::|.| .:.:.|.:..:| ..|..:|:.|||..:
 Worm   586 KVKNRSLDLLSTTQKERLRIAAVFVGQPDLVLIDFPTMECLPEWKFMVF-RFIEKRKEKRSIIVS 649

  Fly   706 SNNQKVASGIADRIFVLSKGKLQAFGTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFMATFIPEI 770
            |.:.:....|:|::.::|:|.:...|:.:.....:|..:.:.|:.|.:.:.:.:...|.|
 Worm   650 SYDPEETEAISDKVVLMSEGYVVLNGSCEAFKHSINSVFEIRIWPNNRFTDEQIKGMMKT----- 709

  Fly   771 EMDSILADCASFLVKHKYHTELINLIENLARLKNDLNVYSFEIHECSIDDILASLYTR------- 828
                                  :.|.:|  ::|||...  ||.....|...|..||.|
 Worm   710 ----------------------LTLGDN--QMKNDARF--FETPNGKIRVTLPILYRRSIPLILR 748

  Fly   829 ------DKSTLEF---GQPGLQTLLAS----RQQSAKRRFIIPTMYLLEELRQLLIADTRNWFLP 880
                  :|..:||   |:|.:..:.|:    .||       :..:...::||     |......|
 Worm   749 ELDAVHEKFRIEFYELGKPNIHDIYANACYEHQQ-------LDPLSTFDQLR-----DHYTKQQP 801

  Fly   881 ILKLTLPSLVVVWTLSMPYFWHNCRQPGHITFPMSDHGDG------------------IILMQKD 927
            :.|.|             ||:.|..   ||      ..||                  |||:...
 Worm   802 LNKKT-------------YFFKNMI---HI------FKDGRFLIETAAVVGLFLILTVIILLSYH 844

  Fly   928 TLDSELLVASEMYAKVGVTEVDKTVDITTFIYNYEYKNSLLSDADIMEAVIFSN----VQIE--- 985
            :::|:    |....::.:|..:..:.    ||..|      .:.:::|.|.|..    :|:|
 Worm   845 SVESD----SHQTREISLTSYESPIT----IYCDE------CEKEVIEGVTFEKKSRVLQLENNQ 895

  Fly   986 -VLFNTKWPHTAP-----------DSL-AQALNSLAVA---------------FIDGDAGIKVEL 1022
             ||:   |..||.           |:| ...:.:.||:               |::.: .::...
 Worm   896 AVLY---WKDTAKADKELITVSRGDALFTMIVQNFAVSQMISKITGKHPQIKLFLESE-NVRTAT 956

  Fly  1023 EVLPFSTI-----HTLQLHLNIDGYDLIFASCLSFCFCFIWSIPL-LHMTLSRDG---------R 1072
            |:..|||:     .:....:..:.|.|::.:.:...|.:.:|:.| |.:..:..|         |
 Worm   957 EISGFSTVFNDISSSKAAMILTESYSLMYITAVFQMFVYTFSVVLPLRLVSTNMGPQSMILPWPR 1021

  Fly  1073 YNYVELIAGMPTIVLIVAFLIYELLVVLLALFPINIAVIFFH----WDLLMDSNIHIYSVYVMFI 1133
            |.|...|.....:|.:|..:|....|:.:..|..|....:..    |.|...|.:.:  :|.:
 Worm  1022 YVYFGFIYVFQLVVFLVIAIILGFAVLSMGFFATNTTSCYLRFLSAWFLSYASTLPL--IYFL-- 1082

  Fly  1134 IAACVFSLNILITIMPISDMPFVYLKVLLAYSLGILVYIAVKELRPFTNPNTAHFLLLDFHPFYA 1198
                ||::....:::||         :|...||.:            |.||    |:..|.
 Worm  1083 ----VFNIQNTKSVIPI---------ILAISSLSV------------TFPN----LVASFS---- 1114

  Fly  1199 LLHNLMRIASISEKI-WLC-----SDRQIYETSVYADQCNTIPNCCDDDAQEFYHLRYLCCVYLL 1257
             ..|.:.:.|:.:.: |.|     |..|:....:.|.:      ..:.::.....|...|.....
 Worm  1115 -AENQVSLQSLIQFVSWSCMLNPPSSLQVLAAFLNAGE------SLEKNSGTITSLILFCGAQFW 1172

  Fly  1258 LVVVWISIFIFLKSHMVKRRPRQPKY-----FWDSDPD---SKYDQNILHIMEP-SELENTWIHE 1313
            ::|::: :.||           ||.:     :|.....   |.:::..  .::| :.::|::|..
 Worm  1173 IIVIFV-LVIF-----------QPGFSYIQQYWFKSSTVLYSSFERGT--TLKPGARIKNSYIFV 1223

  Fly  1314 KSRVSTLE--------------------------RNHIESKALHVEHLSVFFGLKAAIKHIDFMV 1352
            .:.:.|:|                          .::|...::.::.:|..      ..:.:.:|
 Worm  1224 TNPLGTMEDAQDKGASGNIPNRPAAGTEPVQKPTSDYIAGSSMSIDDMSYI------TNYEENLV 1282

  Fly  1353 NRYQVMS----------------VFGANGTGKSVLLKTILGI-------YTPSSGRIISSKTVPF 1394
            .:...|:                :.|.....||.||.||..|       :.|.... ||:...||
 Worm  1283 EKMATMTSWNDKQEVPVDNSATFLMGDQTKLKSALLTTIAKINKNEHIAFVPIVEN-ISTIYTPF 1346

  Fly  1395 KSKDLDSCHMVGYSAQEFQTMQLMTILETWDLILRIRRSKQISFRAEATKLCKIFGLYKYRFNSL 1459
            :..: ::.:..|:   |.....:..:|:.:||            :..|....|:......|.  |
 Worm  1347 ELLE-NAAYCNGF---EITDDHISYLLDAFDL------------KEHANTQIKLLPCIDRRI--L 1393

  Fly  1460 SICSQGVLKRLSLGIALMSDAELILLDDPFTHLDIVSQRSMLHIIHDLRRRGHSIIYTCSDTAYS 1524
            .:.::.|:|           ..::::|.....|......::......||:.|..||||...:.::
 Worm  1394 MLLAKLVIK-----------PNIVIIDQLEMFLPHSKMMTVWSFCARLRKNGLGIIYTSHHSGFA 1447

  Fly  1525 TPALRMATLSYPG 1537
            ..........|.|
 Worm  1448 EHTATCCAHMYKG 1460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	112/518 (22%)
		ABC_subfamily_A	519..737	CDD:213230	53/220 (24%)
		P-loop_NTPase	1330..1517	CDD:422963	34/209 (16%)
abt-1	NP_001293854.1	rim_protein	<256..>676	CDD:130324	103/485 (21%)
		P-loop_NTPase	474..677	CDD:393306	53/216 (25%)
		ABC2_membrane_3	<917..1176	CDD:378925	51/303 (17%)
		CcmA	<1328..1491	CDD:224054	27/163 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160135
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850