Protein Alignment CG43672 and abt-2

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: NP_490949.3
• Gene: abt-2 / 171782
• WormBaseID: WBGene00000020
• Length: 2146
• Species: Caenorhabditis elegans
• Alignment Length: 1902
• Identity: 381/1902 - (20%)
• Similarity: 688/1902 - (36%)
• Gaps: 513/1902 - (26%)

  Fly    13 VWKNFQKQKHNKLVLILSLVLPVMSSLFL--LFIRSSSDSNMRDYSIRAEAELLEFSWSSLIGKI 75
            |:||.|.|.:.:.:           ..||  ||..||.                |:|:.:....|
 Worm   488 VYKNGQNQLNTRTI-----------HFFLEHLFAPSSD----------------EYSFGTYTKNI 525

  Fly    76 QERRAKMASKQRNFTTNVFIPDIRVAFAPNSNAALRRLMGDALGKLSMSEDKIVDFENCNDMRIH 140
            .|    :|:|.    |..|:.| |..|                    ::::|.::......|..|
 Worm   526 TE----IANKY----TGCFLLD-RFRF--------------------VTDEKELETNAVCLMDTH 561

  Fly   141 AASEHYLASVCFRNVDES---LNGLPTVLNFAIIMPSELRNYEDTWIGDSWKETTTLMDRDVAEE 202
                .|...:.| |:|.:   .:|..|.         ::|:|.:  :.||   ||:.||   ::.
 Worm   562 ----QYFTGIVF-NIDSNATEFDGFTTY---------KIRHYPE--MVDS---TTSFMD---SKS 604

  Fly   203 DEFDEDG---YTDYMGEGFVPLQYHISMQFLRATASKV--------------EKLPKVVMRRFNE 250
            :.|..|.   ...|:..||..||..|.    ||..|::              |..|..|...||
 Worm   605 NPFSRDKPLIDLKYITFGFSFLQESID----RAIMSELTNQTDANLGVYAQQEPYPCTVKDTFN- 664

  Fly   251 NPNVLLSEGIGTSVVLLILLGFMFPVTILTTLIVEERELGQRYMLKILNASATLQMAAW-FFNVF 314
                     :...:.|.:|:.|:||..:|...||.|:|...:..::.:.....:...:| ..::.
 Worm   665 ---------VALFMPLFLLISFIFPSALLVKNIVYEKEQKIKEQMRAMGLGDAVHFISWGLISLV 720

  Fly   315 THFLITSLLITILLKIEWNGATAAVNKCPWPILLCFLISYGCSVTSLIILMTSAMRRSRVAMVMA 379
            .:| |:.|:|:|:.|:     ....:...:.:||..||.:..|..::.|..::....:.:|....
 Worm   721 LNF-ISVLIISIISKV-----AKIFDYTDYTLLLFVLILFLFSSIAMSIFFSTLFTNANIATAAT 779

  Fly   380 PIIWILLALPL-LSKKELLSDG---------PDVFYGFATVLL--CNVSFSRGLSKIFYIEDYTL 432
            .::|.:..:|. |.:.:.:|..         |....|....||  .|.......|.::.:.:..|
 Worm   780 CVLWFVFFIPFQLLRTDRISSPTFNRISLILPPTAMGHCFKLLESFNAMERATWSDLWEMNNPVL 844

  Fly   433 GVTIGKYMFYRVSKSDFGIFVPIVCFYVQTI----FCTLLAMIFENNAYFWLAIRVKNLLKKYHA 493
            |:::...|...|  .|..:|: |:.:|:..:    |.....:.|.....:|
 Worm   845 GISVELCMIMLV--VDTAVFL-ILAWYISAVAPGDFGVRQPLWFPFTLKYW-------------- 892

  Fly   494 TRSAVGRLKRQIPEV------------SFSK--TSAEALIEFRGVWQKYSNSTYVVQDITLNVYA 544
               |.|..|.::..|            ||..  |:....:....:.:.|.|.|..:..:.|.:|.
 Worm   893 ---APGLYKNRVEFVDDEHFDTIPNSDSFDSEPTNLTLAVHINSMSKVYENGTKALDCLNLRLYE 954

  Fly   545 GEVVALLGHNASGKSTIIKMLYGRTRPKLGEIYLSGFNIVTQRKEALKNSSISMSYKTLFTELVV 609
            |::..|||||.:||:|.:.:|.|...|..|...:...:|.|..:.......|...:..||:.|.|
 Worm   955 GQITGLLGHNGAGKTTTMSILCGLYAPSSGTAKIYQRDIRTDLRRVRDVLGICPQHNVLFSHLTV 1019

  Fly   610 LDHLVFLSRLRGLSKTEAKLEAKALLRYLKLEDWEKTLVNDLTIGQRRVLQFLCAFAGGNQIVIL 674
            .:.|...:.|:|:..:|...:...:|..:.|.:....|.:.|:.|.:|.|....||.||::.|||
 Worm  1020 SEQLRLFAALKGVPDSELTSQVDEILASVSLTEKANKLASTLSGGMKRRLCIGIAFIGGSRFVIL 1084

  Fly   675 DKPFDGIDEQRTSLFYSLILDQKKNRSIFFTSNNQKVASGIADRIFVLSK---------GKLQAF 730
            |:|..|:|.......:.|:...|:.|:|..::::...|..::|||.:||:         ||...|
 Worm  1085 DEPTAGVDVTARKDIWKLLQRNKEGRTILLSTHHMDEADVLSDRIAILSQDFEKPDLLDGKRLIF 1149

  Fly   731 GTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFMATFIPEIEMDSILADCASFLVKHKYHTELINL 795
                      ...|.|::     |..........||:.::.:...|...|...|..:..|...:|
 Worm  1150 ----------QHFYALLV-----CRINYTLKSKRTFLFQVIIPLFLLALAELFVLLQVSTARPDL 1199

  Fly   796 IENLARL---------KNDLNVYSFEIHE--------------------CSID---DILASL--- 825
            :.::..|         .:|..|.|::..|                    |:.|   |:|.::
 Worm  1200 MVSMPPLPLETSIMGNHSDFYVNSWDTAENSTANDILHAMFSSPGTGPRCAKDVPNDLLDTMRRE 1264

  Fly   826 -------------------------------------YTRDKSTLEFGQP--------GLQTLLA 845
                                                 ||.|.|...:..|        |....|.
 Worm  1265 LMFRNRYGFGRNKPAPGVDKDSVDNEYQCQNIQGEFDYTEDISNATYNAPIYCGCEDFGWNCTLE 1329

  Fly   846 S---------RQQSAKRRFIIPTMYLLEELRQLLIADTRNWFLPILKLTLPSLVVVWTLSMPYFW 901
            .         |..:..|.|.: |...|.:.|.:    ||  |..:...|.|..:..::|
 Worm  1330 DWKWNETNWLRLNTTDRIFDL-TGRNLTQFRLI----TR--FAQLANTTAPFFLGGFSL------ 1381

  Fly   902 HNCRQPGHITFPMSDHGDGIILMQKDTLDSELLVASEM-YAKVGVTEVD----KTVDITTFIYNY 961
                  ||:........| |...::..|::...:|..| ...:..|.::    |.:|  .|..|.
 Worm  1382 ------GHVNQRAQSQAD-IDTSKRGWLETIKDIAQSMRIINLNTTGIEPATPKVLD--PFAQNI 1437

  Fly   962 ---EYKNSLLSDADIMEAVIFSNVQIEVLFNTK-WP--HTAPDSLAQALNSLAVAFIDGDAGIKV 1020
               :..|.||.:.|:.|       .::|.||.| ||  ..|.:.|:.||.......||.:
 Worm  1438 TLNQVVNDLLQNLDVRE-------NVKVWFNNKIWPGFPIASNILSNALLRQEDYAIDPE----- 1490

  Fly  1021 ELEVLPFSTIHTLQLHLNIDGYDLIFASCLSFCFCFIWSIPLLHMTLS-------------RDGR 1072
            :|.:|..:......:...:|...|.|...|:     ::.|.:|.:.||             |...
 Worm  1491 DLGILTMNHPMNKTISQTLDQNALKFTQALA-----VFRITILLLVLSMIPAGFTVYLVEDRICE 1550

  Fly  1073 YNYVELIAGMPTIVLIVAFLIYELLVVLLALFPINIAVI-------------FFHWDLL-----M 1119
            ..:::|:.|:..:...|...:|:::|..|.:..|.:..:             ||.:.||     |
 Worm  1551 ALHLQLVGGLRKVTYWVTSYLYDMVVYTLVIIVIMLIYLCFRVSDFTADGATFFAFLLLFFVHGM 1615

  Fly  1120 DSNIHIYSVYVMFIIAACVFSLNILITIMPISDMPFVYLKVLLAYSLGILVYIAVKELRPF--TN 1182
            .:.::.|.....|.:||..|   :||.|.              :|.:||:..:.|..|...  .:
 Worm  1616 STILYAYVFQKAFSVAALSF---VLIAIG--------------SYFVGIVCALTVIMLESLMVQD 1663

  Fly  1183 PN--TAH------FLLLDFHPFY----ALLHNLMRIASISEKIWLCSDRQIYET----SVYADQC 1231
            |:  .||      ||:|   |.|    |:...||                ||:.    |.:..|.
 Worm  1664 PSLIPAHTVCSIVFLVL---PQYNLGIAIFRGLM----------------IYQVRAIGSNFLQQM 1709

  Fly  1232 N--------TIPNCCDDDAQEFYHLRYLCCVYLLLVVVWISIFIFLKSHM-----VKRRPRQPKY 1283
            |        .:|:....|....    ::.|:::.:::..|.: ||  |.|     |::|.|
 Worm  1710 NRPDMINQLPLPSLLAFDQMGI----HIMCLFIHVIIATICL-IF--SQMDEFGFVRKRER---- 1763

  Fly  1284 FWDSDPDSKYDQNILHIM---EPSELEN-TWIHEKSRVSTLERNHIESKALHVEHLSVFFGLK-A 1343
                        |:...|   |||..:: ..:.|:.||..:..:..::.||.|.:|:..:..: .
 Worm  1764 ------------NLTDAMMLREPSTCDDEDVVKERQRVDAIPMDSSDNHALIVRNLAKAYNPELL 1816

  Fly  1344 AIKHIDFMVNRYQVMSVFGANGTGKSVLLKTILGIYTPSSGRIISSKT-VPFKS-KDLDSCHMVG 1406
            |:|.|.|.|...:...:.|.||.||:.....:.....|..|.|....| :...| .|:.:...:|
 Worm  1817 AVKGISFAVEPGECFGLLGLNGAGKTTTFAMLTAKIRPGHGSIEMQNTRINTGSFSDVRNFQQLG 1881

  Fly  1407 YSAQEFQTMQL-MTILETWDLILRIRRSKQISFRAEATKLCKIFGLYKYRFNSLSICSQGVLKRL 1470
            |..| |..:.: ::..|......|||........:...:|.....|..|.....|..|.|..::|
 Worm  1882 YCPQ-FDALNMKLSTRENLKFYARIRGIVPTQIDSIIDRLLIALHLRPYANTQTSSLSGGNRRKL 1945

  Fly  1471 SLGIALMSDAELILLDDPFTHLDIVSQRSMLHIIHDLRRRGHSIIYTCSDTAYSTPAL--RMATL 1533
            |:.:||:|...||.||:|...:|..||:.:..:|..|.:.|.:::.| |.:.....||  |:|.:
 Worm  1946 SVAVALVSQPSLIFLDEPSAGMDPGSQQFLWKVIERLCKSGKAVVLT-SHSMEECEALCTRIAIM 2009

  Fly  1534 SYPGIAVIGEREEMQQNYYSSYYMVETRIHLAELGSPIDFDSQSTEAKEDRAGTTGTLLRHKHQE 1598
            ....|..:|.::.::..|..              ||.:.......|..::.||    ::|.|..:
 Worm  2010 DRGRIRCLGGKQHLKSKYGK--------------GSMLTMKMGKDENAKEIAG----IMRSKLGD 2056

  Fly  1599 FSAAFTDSADRWKYLKLCGVIENVFPHAIIKNVSFPRVCFWLSSHMYPMSRIVDTLHRNKQ--DF 1661
            .|.                          ::.:....:...:......::|:::.:::.|:  |.
 Worm  2057 GSR--------------------------VEAIHCSTIFIHIEQGTASVARVLEIVNQVKKMYDV 2095

  Fly  1662 YSFSVSQPSVNSVFLSI 1678
            ..|:::|.::::||.||
 Worm  2096 DDFTLTQSTLDNVFQSI 2112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	112/505 (22%)
		ABC_subfamily_A	519..737	CDD:213230	60/226 (27%)
		P-loop_NTPase	1330..1517	CDD:422963	49/190 (26%)
abt-2	NP_490949.3	rim_protein	39..2117	CDD:130324	381/1902 (20%)
		ABC_subfamily_A	929..1134	CDD:213230	56/204 (27%)
		ABC_subfamily_A	1802..2024	CDD:213230	57/223 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020