Protein Alignment CG43672 and abca10

DIOPT Version :9

• Sequence 1: NP_788912.3
• Gene: CG43672 / 318910
• FlyBaseID: FBgn0263747
• Length: 1690
• Species: Drosophila melanogaster
• Sequence 2: XP_031750511.1
• Gene: abca10 / 100485734
• XenbaseID: XB-GENE-6464279
• Length: 1610
• Species: Xenopus tropicalis
• Alignment Length: 1834
• Identity: 346/1834 - (18%)
• Similarity: 702/1834 - (38%)
• Gaps: 417/1834 - (22%)

  Fly    12 LVWKN----FQKQKHNKLVLILSLVLPVMSSLFLLFIRSSSDSNMRDYSIRAEAELLEFSWSSLI 72
            |.|||    ::::.|:.|..:.:|..     :||:|:..:.:.    |...::.:|.. :|  ::
 Frog    18 LFWKNLLLKWRRKWHSTLEWLQNLAF-----VFLMFLTVAIEL----YGPTSDIDLSP-AW--VL 70

  Fly    73 GK--------------------IQERRAKMASKQRNFTTNVFIPDIRV-AFAPNSNAALRRLMGD 116
            |:                    |.|:.||          .:.:|||:| .||
 Frog    71 GRLDAFNNLSVGYVHTTSTSRDIMEKVAK----------GIIVPDIKVQEFA------------- 112

  Fly   117 ALGKLSMSEDKIVDFENCNDMRIHAASEHYLASVCFRNVDESLNGLPTVLNFAIIMPSELRNYED 181
                   .|:::::          |.|...:.:|.|  |||        .::.|......|.:.:
 Frog   113 -------DEEELIE----------AVSNMSMVAVTF--VDE--------FSYHIRYQLPKRKHPN 150

  Fly   182 ---TWIGDSWKETTTLMDRDVAEEDEFDEDGYTDYMGEGFVPLQYHISMQFLRATA-----SKVE 238
               .::|:.              .|:......|.|..|||:.||..|....:..|:     :.:.
 Frog   151 DYFAYMGNC--------------GDDLSYCNPTYYWSEGFLSLQASIDSAIIDLTSNHSVWNNMA 201

  Fly   239 KLPKVVMRRFNENPNVLLSEGIGTSVVLLILLGFMFPVTILTTLIVEERELGQRYMLKILNASAT 303
            .:..:.|:....:..||........|:.:..:..|:   :|:..:..|| ...:..|:::.....
 Frog   202 SIVAIKMKSAERSYKVLAHVASFIFVMPMCYVSLMY---LLSQYVTRER-YEMKETLRLMRLQDL 262

  Fly   304 LQMAAWFFNVFTHFLITSLLITILLKIEWNGATAAVNKCP-------WPILLCFLISYGCSVTSL 361
            ....:|......:..|.:.|:|::.|             |       :.|::.....||.::.|.
 Frog   263 AFWLSWGLLYSCYVFIVANLMTLVTK-------------PFVFITSSYGIIMFMFFLYGVALMSF 314

  Fly   362 IILMTSAMRRSRVAMVMAPIIWILLA---LPLLSK------KELLSDGPDVFYGFATVLLCNVSF 417
            ..::::..|..|...:....|.:||:   |.||||      :.|||..|.  :.||..:..:|..
 Frog   315 TFMLSALFRNPRATAIAGFFITLLLSALGLILLSKHVPKSVEVLLSIFPQ--FAFAVGITQSVHM 377

  Fly   418 SRGLSKIFYIEDYTLGVTIGKYMFYRVSKSDFGIFVPIVCFYVQTIFCTLLAMIFEN-------- 474
            ......: |..|.|.|           |......|:.:|   :.::|...|.:.||.
 Frog   378 ENDQEGV-YFSDLTGG-----------SSHMLSCFISLV---LDSVFYMGLTLYFEKVLADKHGV 427

  Fly   475 --------NAYFWLAIRVKNLLKKY-HATRSAVGRLKRQIPEVSFSKTSAEALIEFRGVWQKY-- 528
                    .|.:|...:...|:.:. .:..|::|....::|.....|.:    |...||.:.|
 Frog   428 KHEPLFFLKASYWSKEKPSPLMAQTDDSGESSLGHFVEKVPADLHGKEA----IRIHGVKKTYYD 488

  Fly   529 -SNSTYVVQDITLNVYAGEVVALLGHNASGKSTIIKMLYGRTRPKLGEIYLSGFNIVTQRK--EA 590
             ..:|..::|:.||:|.|::.|||||:.:||:|::.:|.|......|...:..:.:...|.  |.
 Frog   489 KDKNTEALRDLDLNIYEGQITALLGHSGAGKTTLLNILSGMCPTSGGSATVCNYKLSNMRHLGEI 553

  Fly   591 LKNSSISMSYKTLFTELVVLDHLVFLSRLRGLSKTEAKLEAKALLRYLKLEDWEKTLVNDLTIGQ 655
            .|...........|..|.|.::|...:.::|:...|...:.:.:|..|::.|.|....:.|:.||
 Frog   554 KKRVGFCPQGDIKFDPLTVKENLTVFAMIKGIPSKEVAHKVQTVLSDLQMNDIENIEASKLSGGQ 618

  Fly   656 RRVLQFLCAFAGGNQIVILDKPFDGIDEQRTSLFYSLILDQKKNRSIFFTSNNQKVASGIADRIF 720
            :|.|.|..|..|..|:::||:|..|:|.......::::.:.|.:|....::.....|..:|||..
 Frog   619 KRKLTFGIAILGDPQVLLLDEPTAGLDPCSRHNIWTILKESKADRVTLLSTQFMDEADILADRKV 683

  Fly   721 VLSKGKLQAFGTVKKLCRMLNESYRLIIFGNEKCSFKDVYAFMATFIPEIEMDSILADCASFLVK 785
            |:|||||:..||...|.|.....|.|.:..:..|..:.:.:.:...||..::.:...:..::.:.
 Frog   684 VISKGKLKCVGTSLFLKRKWGVGYHLRMQVSPSCDVELMTSIIKQHIPSTKLTTQNEEELTYTLP 748

  Fly   786 HKYHTELINLIENL-ARLKNDLNVYSFEIHECSIDDILASL------------------------ 825
            .:......:|..:| .::.|  ::.::.:...::||:...|
 Frog   749 FENMDVFPDLFLHLDGQVGN--SIVNYGVSMTTLDDVFLKLEGEGEIESGDYDVFNPESRTNEDR 811

  Fly   826 ----YTRDKSTLEFGQPGLQTLLASRQQSAKRRFIIPTMYLLEELRQLLIADTRNW---FLPILK 883
                ...::|.|:....|..||  |..:..:::.:......|.:||.    ||:::   .|.::.
 Frog   812 EDFSTEMEESLLQMSDSGNVTL--SGWELWRQQVLAVARIRLLKLRH----DTKSFRSILLLLVV 870

  Fly   884 LTLPSLVVVWTLSMPYFWHNCRQPGHITFPMSDHGDGIILMQKDTLD---SELLVASEMYAKV-- 943
            :|||.::::.|.::...:.......|:.|.          ..::.|:   ::||:.:...:.:
 Frog   871 ITLPPIIIIITSNIVNTFDAWELTPHLYFQ----------SPRNRLNKYYTDLLICNNTGSSIED 925

  Fly   944 ---GVTEVDKTVDITTFIYNYE---YKNSLLSDADIMEAVIFSNVQIEVLFNTKWPHTAPDSLAQ 1002
               .|.|.:..|.:....|:.|   |:.::  :...||    ......::.|.|    |.:||..
 Frog   926 FVGAVKEQNIEVQVVNGEYDTETVKYRGAI--EVSQME----KGYNFTIVANPK----AFNSLPV 980

  Fly  1003 ALNSLAVAFIDGDAGIKVELEVLPFSTIHTLQLH-LNIDGYDLIFASCLSFCFCFIWS---IPLL 1063
            .||.::.|.          |::|..|....:..| :..||.|:||...:|..|..|::   .|.:
 Frog   981 LLNIISNAL----------LKILKVSGHFRVWNHPITTDGTDIIFLPYMSLIFFIIFASAFCPHI 1035

  Fly  1064 HMTLSRDGRYNYVELIAGMPTIVLIVAFLIYELLVVLLALFPINIAVIFFHWDLLMDSNIHIYSV 1128
            .|:.:.|.|.|....:.                   :..|||    ..::....|:|  :.:|.:
 Frog  1036 AMSSTEDNRINARNQLR-------------------ISGLFP----SAYWFGQALVD--VILYWI 1075

  Fly  1129 YVMFIIAACVFSLN--ILITIMPISDMPFVYLKVLLAYSLGILVYIAVKEL-----RPFTNPNTA 1186
             ::|::.|..|:.|  ||:..:|    ..|.:..::.|...:::|:.|...     :..|:..:.
 Frog  1076 -LLFLMVAIYFAFNSYILLDFVP----AMVMIIGIIGYGTAMVLYVYVISFIFGRGKSHTDSWSL 1135

  Fly  1187 HFLLLDFHPFYALLHNLMRIASISEKIWLCSDRQ-IYETSVYADQCNTIPNCCDDDAQEFYHLRY 1250
            .|::....|...:...:.|:.:|...::..|... |.|   |..:....|.     ..|:..|..
 Frog  1136 FFVITSTFPVMFMDVFMFRLFTIYYFVFPASALSGIME---YTYRLQVFPG-----GSEYTALIE 1192

  Fly  1251 LCCVYLLLVVVWISIFIF-----LKSHMVKRRPRQPKYFWDSDPDSKYD-QNILHIMEPSELEN- 1308
            .|..||.:::.::.::..     |:|..:             ||..:.. :.|.....|.||.|
 Frog  1193 QCTPYLHIIIFFVLLWFLEWKFGLRSLTI-------------DPLFRISRRKITTKKNPEELGND 1244

  Fly  1309 ---TWIHEKSRV---STL----ERNHIESKALHVEHL----SVFF--GLKAAIKHIDFMVNRYQV 1357
               ..:.||.||   :|:    |:..|.:.:|..|:.    ..||  ..:||.|::.|.|.:.:|
 Frog  1245 VDEDVLAEKERVKKAATIANVEEKPVIIADSLRKEYKVKKGGSFFKKNKRAATKNVSFCVKKGEV 1309

  Fly  1358 MSVFGANGTGKSVLLKTILGIYTPSSGRIISSKTVPFKSKDLDSCHMVGYSAQEFQTMQLMTILE 1422
            :.:.|.||.||:..:..:.|...|::|.::.....|     :.|...:||..|:......:|:.|
 Frog  1310 LGLLGPNGAGKTTSMYMLAGEVKPTAGEVLLCGNDP-----VGSTGFLGYCPQDNPLWPNLTVKE 1369

  Fly  1423 TWDLILRIRRSKQISFRAEATKLCKIFGLYKYRFNSLSICSQGVLKRLSLGIALMSDAELILLDD 1487
            ..::...::..|:........::.....|.::...:....|.||.:::...|:::.:..::|||:
 Frog  1370 HLEIYAAVKGMKKEDASIAINRVASALELKEHMGKAARKLSLGVSRKVCFAISMLGNPNIVLLDE 1434

  Fly  1488 PFTHLDIVSQRSMLHIIH-DLRRRGHSIIYTCSDTAYSTPAL----RMATLSYPGIAVIGEREEM 1547
            |.|.||...|:.:...|. ..:.:....|.|   |.|...|.    |:|.:....:..||..:::
 Frog  1435 PSTGLDPKGQQRLWRAIRAAFKNKDRGAILT---THYMEEAEAVCDRVAIMVSGKLRCIGSIQQL 1496

  Fly  1548 QQNYYSSYYMVETRIHLAELGSPIDFDSQSTEAKEDRAGTTGTLLRHKHQEFSAAFTDSADRWKY 1612
            :.. :...|::|.::                              :..||         .|
 Frog  1497 KSK-FGKGYLLEIKV------------------------------KESHQ---------VD---- 1517

  Fly  1613 LKLCGVIENVFPHAIIKNVSFPRVCFWL-SSHMYPMSRIVDTLHRNKQDF----YSFSVSQPSVN 1672
             ::...|..:||||..::.....:.:.: ..::..:|:....|...|:.:    |||  ||.::.
 Frog  1518 -QIHNEIIRIFPHAARQDRFSSLLVYKIPMDNVQSLSQAFLLLEEAKRAYNIEEYSF--SQSTLE 1579

  Fly  1673 SVFLSIHRQKSNKD 1686
            .||:.:.:::..:|
 Frog  1580 QVFIELAKEQEKED 1593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43672	NP_788912.3	rim_protein	<266..>732	CDD:130324	110/503 (22%)
		ABC_subfamily_A	519..737	CDD:213230	62/222 (28%)
		P-loop_NTPase	1330..1517	CDD:422963	41/193 (21%)
abca10	XP_031750511.1	rim_protein	<107..1597	CDD:130324	325/1723 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010