Protein Alignment Apf and NUDT2

DIOPT Version :9

• Sequence 1: NP_723505.2
• Gene: Apf / 318908
• FlyBaseID: FBgn0051713
• Length: 142
• Species: Drosophila melanogaster
• Sequence 2: NP_001152.1
• Gene: NUDT2 / 318
• HGNCID: 8049
• Length: 147
• Species: Homo sapiens
• Alignment Length: 140
• Identity: 66/140 - (47%)
• Similarity: 87/140 - (62%)
• Gaps: 8/140 - (5%)

  Fly     3 KAAGFVIFRRLC-------GEIQYLLLKASYGSFHWSSPKGHVDPGEDDFTTALRETKEEAGYDE 60
            :|.|.:|||| |       ..|::|||:||.|..||:.|||||:|||||..||||||:||||.:.
Human     4 RACGLIIFRR-CLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEA 67

  Fly    61 KDLIIYKDTPLTLNYQVQDKPKIVIYWLAELRNPCQEPILSEEHTDLKWLPKEEAKQCVGFKDNQ 125
            ..|.|.:.....|||..::|||.|||||||:::...|..||.||...:||..|||.|...||:.:
Human    68 GQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMK 132

  Fly   126 VMIDKFHQMI 135
            ..:.:.||.:
Human   133 AALQEGHQFL 142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Apf	NP_723505.2	Ap4A_hydrolase_human_like	1..133	CDD:239520	64/136 (47%)
NUDT2	NP_001152.1	Ap4A_hydrolase_human_like	2..140	CDD:239520	64/136 (47%)
		Nudix box	43..64		16/20 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6476
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H896
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4747
Isobase	1	0.950	-	0	Normalized mean entropy	S4140
OMA	1	1.010	-	-		QHG62350
OrthoDB	1	1.010	-	-		D1107148at2759
OrthoFinder	1	1.000	-	-		FOG0004403
OrthoInspector	1	1.000	-	-		oto88647
orthoMCL	1	0.900	-	-		OOG6_104771
Panther	1	1.100	-	-	LDO	PTHR21340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2399
SonicParanoid	1	1.000	-	-		X4204
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.820