Protein Alignment tplus3b and RTF1

DIOPT Version :10

• Sequence 1: NP_724376.1
• Gene: tplus3b / 318905
• FlyBaseID: FBgn0051703
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_011270.1
• Gene: RTF1 / 852607
• SGDID: S000003213
• Length: 558
• Species: Saccharomyces cerevisiae
• Alignment Length: 413
• Identity: 77/413 - (18%)
• Similarity: 161/413 - (38%)
• Gaps: 71/413 - (17%)

  Fly     2 DERLRTRRKIANKLESGGKTAHAFERLLAIRTIKLSKGKCSEDSAEQTKSSDDCKAQTRKDVNIE 66
            ||..|..|.......:.|.:.....:|..::..:..|.:...|:.::    ||.:....:|...:
Yeast   140 DEDSRKTRASTRSTHATGHSDIKASKLSQLKKQRARKNRHYSDNEDE----DDEEDYREEDYKDD 200

  Fly    67 VKETYSGDSSPN-----------SESENTAQNDPQMNVESEERVSNLEQLSRAVLKRNDIKNLLG 120
            ....|..|...|           .|.|...:.|.|   :.|..:|:..:|.   :.|:.:.....
Yeast   201 EGSEYGDDEEYNPFDRRDTYDKREEVEWAEEEDEQ---DREPEISDFNKLR---IGRSFVAKFCF 259

  Fly   121 KPIFAEAVIGSFVRLNVG----KVYSIYETIALHQD--SKDYRVDGKRTNLILVLRCGSEKRYSR 179
            .|.|.:||.|.:.|:|||    ...:.|..:.:.:.  .|.|.:....||....:..|.:::..:
Yeast   260 YPGFEDAVKGCYGRVNVGTDKRTGKTSYRMVRIERVFLQKPYNMGKFYTNQYFGVTQGKDRKVFQ 324

  Fly   180 IDVVSNQPITQKEFLLWLETNLRNRCTLPTLNDIAKKQVQVKNACKYSYTETDVEKLIQ-----D 239
            ::..|:....:.|:..:|.....::...|:|:.::.|..:|.:......|:...:::::     :
Yeast   325 MNYFSDGLFAEDEYQRYLRALDNSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFN 389

  Fly   240 KKEAG---------IKQNAAYRKISLIIERDMA---AGMNDVEKVQVLEKKILEIDEEPRPQI-E 291
            ||.:|         :::...|.| ....|:|:|   |.:.:.||...:.:|..|.|:....:: |
Yeast   390 KKLSGTNAVLEKTVLREKLQYAK-ETNNEKDIAKYSAQLRNFEKRMSVYEKHHENDQSDIKKLGE 453

  Fly   292 KTGQHRYQVLSSTRGV-HV---------------------PTIYRHELGVPSGGKSSFVKRTAKP 334
            .|.::|...:|:.|.. ||                     ..:|..|:......|:   |..|:.
Yeast   454 LTSKNRKLNMSNIRNAEHVKKEDSNNFDSKSDPFSRLKTRTKVYYQEIQKEENAKA---KEIAQQ 515

  Fly   335 EQHELEKYMRRKYKKSAVVSRSR 357
            |:.:.:|..:.|.:|..:|::.|
Yeast   516 EKLQEDKDAKDKREKELLVAQFR 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tplus3b	NP_724376.1	COG5296	<30..>284	CDD:227615	52/287 (18%)
		Plus-3	105..199	CDD:460817	20/99 (20%)
RTF1	NP_011270.1	COG5296	1..558	CDD:227615	77/413 (19%)