Protein Alignment tplus3b and rtfo-1

DIOPT Version :10

• Sequence 1: NP_724376.1
• Gene: tplus3b / 318905
• FlyBaseID: FBgn0051703
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_505473.1
• Gene: rtfo-1 / 179345
• WormBaseID: WBGene00009103
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 461
• Identity: 109/461 - (23%)
• Similarity: 208/461 - (45%)
• Gaps: 67/461 - (14%)

  Fly     2 DERLRTRRKIANKLESGGKTAHAFERLLAIRTIKLSKGKCSEDSAEQTKSSD-----------DC 55
            ::.::|.::  .|:.|||..|.:.:|       |.|....||..|...:.||           |.
 Worm   132 EKGVKTEKR--RKMNSGGSDAGSPKR-------KASSDSDSEMDAAFHRPSDINRKHKEKNAMDA 187

  Fly    56 KAQTRKDVN--------IEVKETY---SGDSSPNSESENTAQNDPQMNVESEERVS--------- 100
            ....||::.        :.:...:   ||.||.:|.|| ::::.......|.||||
 Worm   188 LKNKRKEIEKKNAKNEALSIDAVFGANSGSSSSSSSSE-SSRSSSSSRESSPERVSEKDKIVKKD 251

  Fly   101 --NLEQLSRAVLKRNDIKNLLGKPIFAEAVIGSFVRLNVGKV------YSIYETIALHQDSKDYR 157
              .|.:|.||.|.|:.:..::..|.|...|:|.:|||..|::      |.|::.:.:.:.:|.|.
 Worm   252 VDGLSELRRARLSRHKLSLMIHAPFFDSTVVGCYVRLGQGQMSGSGSKYRIWKIVGVEESNKVYE 316

  Fly   158 VDGKRTNLILVLRCGSEKRYSRIDVVSNQPITQKEFLLWLETNLRNRCTLPTLNDIAKKQVQVKN 222
            ::||:||.|:..:.|..:|..|:..|||....|.||..||....|:. .|||::.:.||:..::.
 Worm   317 LEGKKTNKIIKCQNGGSERPFRMQFVSNADFEQIEFDEWLLACKRHG-NLPTVDIMDKKKQDIEK 380

  Fly   223 ACKYSYTETDVEKLIQDK-KEAGIKQNAAYRKISLIIERDMAAGMNDVEKVQVLEKKILEIDEEP 286
            |..:.|::.:|:.:|::| |...:.:|.|..|.:...::::|....|:.:.:.::.||.||:.
 Worm   381 AINHKYSDKEVDLMIKEKSKYQTVPRNFAMTKANWSKQKELAQQRGDIREAEQIQTKIDEIER-- 443

  Fly   287 RPQIEKTGQHRYQVLSSTRGVHVPTIYRHELGVPSGGKSSFVKRTAKPEQHELEKYMRRKYKKSA 351
              |.::..:.|.:.:|:...::    :|:...:    |...:....|.|::..:....||.....
 Worm   444 --QADELEKERSKSISAIAFIN----HRNRSKI----KDQVLSGQLKIEENSQDDPFTRKKGGMR 498

  Fly   352 VVSRSRFKKAFEDCVDSSAMVNDIHMESQQKEGDVETETETEKGTE--KDLHSQRLHTFNIELDT 414
            |||.|  |...:..:.:|:...::....:.|...:...|:....|:  |......||.|::::|.
 Worm   499 VVSGS--KSRLDGTLSASSSTTNLSDGGKDKSSSLAKPTQPPPSTQIKKKTDISSLHDFDLDIDL 561

  Fly   415 TGLVPF 420
            ..|..|
 Worm   562 GKLKDF 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tplus3b	NP_724376.1	COG5296	<30..>284	CDD:227615	77/293 (26%)
		Plus-3	105..199	CDD:460817	33/99 (33%)
rtfo-1	NP_505473.1	COG5296	82..503	CDD:227615	96/393 (24%)
		Plus3	252..360	CDD:197843	34/107 (32%)