DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tplus3a and NERD

DIOPT Version :9

Sequence 1:	NP_724373.1	Gene:	tplus3a / 318904	FlyBaseID:	FBgn0051702	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_179241.4	Gene:	NERD / 816147	AraportID:	AT2G16485	Length:	1773	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	94/454 - (20%)
Similarity:	185/454 - (40%)	Gaps:	97/454 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DERLRTRRKIANKLESGGKTAHA--FERLLAIRTIKLSKGKCSEDSAEQTKSSDDCK---AQTRK 61
            |.|.:::....::|::....:|.  ||.|..:.:..|.|        ||.: :||.:   ..|.:
plant   847 DPRRKSQVICDSRLQNLFGKSHVGHFEMLNLLDSHFLKK--------EQNQ-ADDIQGDIVDTEE 902

  Fly    62 DVNIEVKETY-----SGDSSPNSESENTAQNDPQMNVESEERVSNLEQLSRAVLKRNDIKNLL-G 120
            ..:::|.|..     ||........:...:...|.|::....| ::..::...|:|:.:::|| .
plant   903 PNHVDVDENLDHPVKSGKDKKRKTRKKNVRKGRQSNLDDFAAV-DMHNINLIYLRRSLVEDLLED 966

  Fly   121 KPIFAEAVIGSFVRINVG-----KVYSIYETIALHQDSKDYRVDGKRTNLTLVLRCGSEKRYSRI 180
            ...|.|.|..:|||:.:.     .:|.:.:.:...:..:.|:|..|.|:..|.:....:.....|
plant   967 STAFEEKVASAFVRLRISGNQKQDLYRLVQVVGTSKAPEPYKVGKKTTDYVLEILNLDKTEVISI 1031

  Fly   181 DVVSNQPITQ---KEFLLWLETNLRNRCTLPTLND--IAKKQVQVKNACKYSYTETDVEKL--IQ 238
            |::|||..|:   |.....::..|.||.|:..:.:  ||.::|:|||     ..|.::.:.  ::
plant  1032 DIISNQDFTEDECKRLKQSIKCGLINRLTVGDIQEKAIALQEVRVKN-----LLEAEILRFSHLR 1091

  Fly   239 DK-KEAGIKQNAAY-----RKISLIIERDMAAGMNDVEKVQVL------EKKILEI--------- 282
            |: .:.|.::...|     ..::::..|:.      |||:|:|      ::::.||
plant  1092 DRASDMGRRKEYPYLLKLSNSLTMLTLREC------VEKLQLLKSPEERQRRLEEIPEIHADPKM 1150

  Fly   283 -------DEEPRPQIEKSGQHRYQVLSSTRGVHVPTIYRHELGVPSG----GKSSFVKRTAKPEQ 336
                   ||:.:.:.||..|.|.:..|..|....| |...:.|..|.    |.|::...:|..|
plant  1151 DPDCESEDEDEKEEKEKEKQLRPRSSSFNRRGRDP-ISPRKGGFSSNESWTGTSNYSNTSANRE- 1213

  Fly   337 HELEKYMRRKYKKSAVVSRSRFKKAFEDCVDSSAVVNDIHMESQQKEGDVETETETETEKGTEK 400
                  :.|.|.......|..:..:.:|.|..|       |.:..:|.:|:...      |:||
plant  1214 ------LSRSYSGRGSTGRGDYLGSSDDKVSDS-------MWTSAREREVQPSL------GSEK 1258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tplus3a	NP_724373.1	Plus-3	105..198	CDD:281165	23/101 (23%)
NERD	NP_179241.4	PHD5_NSD	601..646	CDD:277043
		SWIB	809..882	CDD:280380	7/34 (21%)
		Plus3	944..1052	CDD:197843	24/108 (22%)
		GYF	1308..1363	CDD:214666
		zf-CCCH	1748..1772	CDD:279036
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4203
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13115
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010