Protein Alignment CG33159 and PRSS22

DIOPT Version :10

• Sequence 1: NP_788455.1
• Gene: CG33159 / 318901
• FlyBaseID: FBgn0053159
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 85/262 - (32%)
• Similarity: 141/262 - (53%)
• Gaps: 29/262 - (11%)

  Fly    17 LPSSSSK----TRIVGGKETTISEVPYLVYLRQNGYFICGGSLISSRAVLSAAHCVYG--SQPEG 75
            :|.:..|    .|:|||:::|.||.|::|.:::||...|.|||::||.|::||||...  ::|..
Human   145 VPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYL 209

  Fly    76 FTVHAGASRLDQEAPVVRN----VVMFHTSPSYS-ATNFDMDVALLQLQEVVVLTPGKVATISPC 135
            |:|..||.:|..  |..|:    |......|.|| ......|:||::|:..:..:...:....|.
Human   210 FSVLLGAWQLGN--PGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPD 272

  Fly   136 RN---PPEGNAYARISGWGVTRENNREPAEQ-VRTTMVRVLPGAECKISY---SGYGQLSDSMLC 193
            .:   ||  |.:..|||||..::....|..| ::...|.::....|...|   :|.|.:::.|||
Human   273 ASIHLPP--NTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLC 335

  Fly   194 AA-VRGLRDSCSGDSGGPLVYRGQ----VCGIVSWGFGCARPSFPGVYTNVASERVHEFIEQTLR 253
            |. :.|.||:|.|||||||:.:..    :.||:|||.|||..:.||||.::::.|  .::|:.::
Human   336 AGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHR--SWVEKIVQ 398

  Fly   254 RI 255
            .:
Human   399 GV 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	81/234 (35%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	82/243 (34%)