Protein Alignment CG33159 and KLK6

DIOPT Version :10

• Sequence 1: NP_788455.1
• Gene: CG33159 / 318901
• FlyBaseID: FBgn0053159
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 81/254 - (31%)
• Similarity: 124/254 - (48%)
• Gaps: 32/254 - (12%)

  Fly    13 LALVLPS-SSSKTRIVGGKETTISEVPYLVYLRQNGYFICGGSLISSRAVLSAAHCVYGSQPEGF 76
            |:|:..: :..:.::|.|.....:..||...|..:|:.:|||.||....||:||||    :....
Human     8 LSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNL 68

  Fly    77 TVHAGASRLDQ------EAPVVRNVVMFHTSPSYSATNFDMDVALLQLQEVVVLTPGKVA-TISP 134
            .|..|...|.|      ::.|||.|:    .|.|.|.:.|.|:.||:|..     |.|:: .|.|
Human    69 QVFLGKHNLRQRESSQEQSSVVRAVI----HPDYDAASHDQDIMLLRLAR-----PAKLSELIQP 124

  Fly   135 C---RNPPEGNAYARISGWGVTRENNREPAEQVRTTMVRVLPGAECKISYSGYGQLSDSMLCAAV 196
            .   |:.........|.|||.|.:.  :..:.::...:.::...||:.:|.  ||::.:||||..
Human   125 LPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYP--GQITQNMLCAGD 185

  Fly   197 RGL-RDSCSGDSGGPLVYRGQVCGIVSWG-FGCARPSFPGVYTNVASERVHEFIEQTLR 253
            ... :|||.||||||||....:.|:|||| ..|.....|||||||.  |...:|::|::
Human   186 EKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC--RYTNWIQKTIQ 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	76/227 (33%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	77/232 (33%)