Protein Alignment CG33159 and KLK12

DIOPT Version :10

• Sequence 1: NP_788455.1
• Gene: CG33159 / 318901
• FlyBaseID: FBgn0053159
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 78/249 - (31%)
• Similarity: 123/249 - (49%)
• Gaps: 22/249 - (8%)

  Fly     2 VGLRLLWWLCHLALVLPSSSSKTRIVGGKETTISEVPYLVYLRQNGYFICGGSLISSRAVLSAAH 66
            :||.:...||.|.|   |.::..:|..|.|...:..|:.|.|.:.....|||.||..|.||:|||
Human     1 MGLSIFLLLCVLGL---SQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

  Fly    67 CVYGSQPEGFTVHAGASRLDQ--EAPVVRNVVMFHTSPSY--SATNFDMDVALLQLQEVVVLTPG 127
            | .||:   :.|..|...|.|  ....:|:.....|.|.|  ::|:.:.|:.||:|:..|.:|
Human    63 C-SGSR---YWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVT-- 121

  Fly   128 KVATISPCRNPPE---GNAYARISGWGVTRENNREPAEQVRTTMVRVLPGAECKISYSGYGQLSD 189
              :::.|...|.:   ......:||||:|........:.::...:.::..|.|...|.  |:::.
Human   122 --SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYP--GRITS 182

  Fly   190 SMLCAAVRGLRDSCSGDSGGPLVYRGQVCGIVSWGF--GCARPSFPGVYTNVAS 241
            :|:||.....:|:|.||||||||..|.:.|:||||.  .|.:...|||||.:.:
Human   183 NMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	71/224 (32%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	71/223 (32%)