Protein Alignment CG33159 and KLK2

DIOPT Version :10

• Sequence 1: NP_788455.1
• Gene: CG33159 / 318901
• FlyBaseID: FBgn0053159
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 82/257 - (31%)
• Similarity: 121/257 - (47%)
• Gaps: 48/257 - (18%)

  Fly    23 KTRIVGGKETTISEVPYLVYLRQNGYFICGGSLISSRAVLSAAHCVYGSQPEGFTVHAGASRLDQ 87
            ::|||||.|......|:.|.:..:|:..|||.|:..:.||:||||:    .:...|..|...|.:
Human    22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL----KKNSQVWLGRHNLFE 82

  Fly    88 EAPVVRNVVMFHTSPSYSATNFDM--------------DVALLQLQEVVVLTPGKVATI-----S 133
            .....:.|.:.|:.| :...|..:              |:.||:|.|     |.|:..:     .
Human    83 PEDTGQRVPVSHSFP-HPLYNMSLLKHQSLRPDEDSSHDLMLLRLSE-----PAKITDVVKVLGL 141

  Fly   134 PCRNPPEG-NAYARISGWGVTRENNREPAEQVR-----TTMVRVLPGAECKISYSGYGQLSDSML 192
            |.:.|..| ..||  ||||     :.||.|.:|     ...:.:|....|..:||  .::::.||
Human   142 PTQEPALGTTCYA--SGWG-----SIEPEEFLRPRSLQCVSLHLLSNDMCARAYS--EKVTEFML 197

  Fly   193 CAAV-RGLRDSCSGDSGGPLVYRGQVCGIVSWG-FGCARPSFPGVYTNVASERVHEFIEQTL 252
            ||.: .|.:|:|.||||||||..|.:.||.||| ..||.|..|.|||.|...|  ::|:.|:
Human   198 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYR--KWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	79/242 (33%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	80/251 (32%)