Protein Alignment CG33159 and KLK1

DIOPT Version :10

• Sequence 1: NP_788455.1
• Gene: CG33159 / 318901
• FlyBaseID: FBgn0053159
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 83/272 - (30%)
• Similarity: 125/272 - (45%)
• Gaps: 40/272 - (14%)

  Fly     7 LWW--LCHLALVLPSSSS----KTRIVGGKETTISEVPYLVYLRQNGYFICGGSLISSRAVLSAA 65
            :|:  || |||.|..:.:    ::|||||.|......|:...|.....|.|||.|:..:.||:||
Human     1 MWFLVLC-LALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAA 64

  Fly    66 HCVYGSQPEGFTVHAGASRL-DQEAPVVRNVVMF-HTSPSYSATNFDM----------------D 112
            ||:    .:.:.:..|...| |.|     |...| |.|.|:....|:|                |
Human    65 HCI----SDNYQLWLGRHNLFDDE-----NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120

  Fly   113 VALLQLQEVVVLTPGKVATISPCRNPPEGNAYARISGWGVTRENNREPAEQVRTTMVRVLPGAEC 177
            :.||:|.|........|..:......||..:....||||.....|....:.::...:::||..||
Human   121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185

  Fly   178 KISYSGYGQLSDSMLCAA-VRGLRDSCSGDSGGPLVYRGQVCGIVSWGF-GCARPSFPGVYTNVA 240
            |.::  ..:::|.|||.. :.|.:|:|.|||||||:..|.:.|:.|||: .|..|:.|.|...|.
Human   186 KKAH--VQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVL 248

  Fly   241 SERVHEFIEQTL 252
            |  ..::||.|:
Human   249 S--YVKWIEDTI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	72/235 (31%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	74/244 (30%)