DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33159 and Prss53

DIOPT Version :9

Sequence 1:	NP_788455.1	Gene:	CG33159 / 318901	FlyBaseID:	FBgn0053159	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	245	Identity:	70/245 - (28%)
Similarity:	113/245 - (46%)	Gaps:	33/245 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TTISEVPYLVYLRQNGYFICGGSLISSRAVLSAAHC---VYGSQPEGFTVHAGASRLDQEAPVVR 93
            |...|.|:...:|:.|..||.|||::...||:||||   :..::...::|..|:.:.:.::|...
Mouse    43 TLPGEWPWQASVRRQGVHICSGSLVADTWVLTAAHCFEKMATAELSSWSVVLGSLKQEGQSPGAE 107

  Fly    94 --NVVMFHTSPSYSATNFDMDVALLQLQEVVVLTPGKVATISPCRNPPEGNAYARISGWGVTREN 156
              .|.......:|:..:...|:|||||....|.|  .:....|..:.|.| |....:||.   :|
Mouse   108 EVGVAALQLPKAYNHYSQGSDLALLQLTHPTVQT--TLCLPQPTYHFPFG-ASCWATGWD---QN 166

  Fly   157 NREPAEQVRTTMVRVLPGAECKISYSGYGQ--LSD----SMLCAAVR-GLRDSCSGDSGGPLVYR 214
            ..:.:..:|...:|::....|...|:...|  ||:    .|||...: |.:..|.||||||::.|
Mouse   167 TSDVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCR 231

  Fly   215 G------QVCGIVSWGFGCARPSFPGVYTNVA------SERVHE--FIEQ 250
            .      || ||:|:...||:...|.:.|::|      ...|||  |:.|
Mouse   232 EPDGHWVQV-GIISFTSKCAQEDTPVLLTDMAVHSSWLQAHVHEAAFLVQ 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	65/232 (28%)
CG33159	NP_788455.1	Tryp_SPc	26..251	CDD:238113	70/245 (29%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		1/2 (50%)
		Tryp_SPc	45..271	CDD:238113	64/232 (28%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100