DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33159 and PRSS36

DIOPT Version :9

Sequence 1:	NP_788455.1	Gene:	CG33159 / 318901	FlyBaseID:	FBgn0053159	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	249	Identity:	88/249 - (35%)
Similarity:	116/249 - (46%)	Gaps:	33/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PSSSSKTRIVGGKETTISEVPYLVYLRQNGYFICGGSLISSRAVLSAAHCVYGS---QPEG-FTV 78
            |..|:  |||||........|:.|.|...|..|||||||:...|||||||...:   :|.. ::|
Human    41 PEPSA--RIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSV 103

  Fly    79 HAGASRLDQEAPV----VRNVVMFHTSPSYSATNFDMDVALLQLQEVVVLTPGKVATISPCRNPP 139
            ..|..  .|:.|:    .|.|.......:||......|:|||:|.....|.|    .:.|...|.
Human   104 LLGVH--SQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGP----AVWPVCLPR 162

  Fly   140 EGNAYAR-----ISGWGVTRENNREPAEQV-RTTMVRVLPGAECKISYSGYG------QLSDSML 192
            ..:.:..     .:|||..:|.:..|...| :...:|:|..|.|:..||..|      |:...||
Human   163 ASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGML 227

  Fly   193 CAAV-RGLRDSCSGDSGGPLVY----RGQVCGIVSWGFGCARPSFPGVYTNVAS 241
            ||.. .|.||:|.||||||||.    |....||.|:||||.|.:.|||:|.||:
Human   228 CAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVAT 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	85/240 (35%)
CG33159	NP_788455.1	Tryp_SPc	26..251	CDD:238113	85/241 (35%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	86/242 (36%)
		Tryp_SPc	47..289	CDD:238113	85/241 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100