DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33127 and Tmprss6

DIOPT Version :9

Sequence 1:	NP_787956.1	Gene:	CG33127 / 318893	FlyBaseID:	FBgn0053127	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_082178.2	Gene:	Tmprss6 / 71753	MGIID:	1919003	Length:	811	Species:	Mus musculus

Alignment Length:	261	Identity:	68/261 - (26%)
Similarity:	104/261 - (39%)	Gaps:	52/261 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 IDGYDVQGVDNVPYLVSLSLTRATYTHLCGASIIGKRWLLTAAHCVDELRTFNGDAVGTP----V 102
            |.|..|......|:..||.:..   .|:||.::|..||::|||||      |..|::.:|    |
Mouse   577 IVGGTVSSEGEWPWQASLQIRG---RHICGGALIADRWVITAAHC------FQEDSMASPKLWTV 632

  Fly   103 YAGIINRSNVTAAQVRY-VDFASTHRSFNGNAGSDNIALLHVSESFEYNARVQQIALPDINDDYS 166
            :.|.:.:::....:|.: |.....|.....::...::|||.:.....|:|.|:.:.||..:..:.
Mouse   633 FLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFE 697

  Fly   167 -NKTAAAYGWGLTDPDGDEYSKELQYAFAPLLNSTGCKELLPADAPLTAQQVCSQV--------- 221
             .:.....|||.....|            |:.|:     |...|..|..|.:||:.
Mouse   698 PGQHCWITGWGAQREGG------------PVSNT-----LQKVDVQLVPQDLCSEAYRYQVSPRM 745

  Fly   222 ----------KTCYGDGGTPLIYWPITGPAELVGLGSWSYMPCGYANRPTVYTSVPPYIGWIHQT 276
                      ..|.||.|.||:....:|...|.||.||. :.||..|...|||.|...|.||.|.
Mouse   746 LCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWG-LGCGRPNFFGVYTRVTRVINWIQQV 809

  Fly   277 I 277
            :
Mouse   810 L 810

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33127	NP_787956.1	Tryp_SPc	41..276	CDD:238113	67/258 (26%)
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	65/255 (25%)
Tmprss6	NP_082178.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48
		SEA	88..185	CDD:279699
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:278486
		Tryp_SPc	576..806	CDD:214473	65/255 (25%)
		Tryp_SPc	577..809	CDD:238113	67/258 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010