DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33127 and ST14

DIOPT Version :9

Sequence 1:	NP_787956.1	Gene:	CG33127 / 318893	FlyBaseID:	FBgn0053127	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	250	Identity:	77/250 - (30%)
Similarity:	115/250 - (46%)	Gaps:	16/250 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 QPLIIDGYDVQGVDNVPYLVSLSLTRATYTHLCGASIIGKRWLLTAAHCVDELRTFN-GDAVGTP 101
            |..::.|.|   .|...:...:||......|:||||:|...||::||||..:.|.|. .|.....
Human   612 QARVVGGTD---ADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWT 673

  Fly   102 VYAGIINRSNVTA--AQVRYVDFASTHRSFNGNAGSDNIALLHVSESFEYNARVQQIALPDINDD 164
            .:.|:.::|..:|  .|.|.:....:|..||......:||||.:.:..||::.|:.|.|||.:..
Human   674 AFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHV 738

  Fly   165 Y-SNKTAAAYGWGLTDPDGDEYSKELQYAFAPLLNSTGCKELLPADAPLTAQQVC-----SQVKT 223
            : :.|.....|||.|...|.. :..||.....::|.|.|:.|||..  :|.:.:|     ..|.:
Human   739 FPAGKAIWVTGWGHTQYGGTG-ALILQKGEIRVINQTTCENLLPQQ--ITPRMMCVGFLSGGVDS 800

  Fly   224 CYGDGGTPLIYWPITGPAELVGLGSWSYMPCGYANRPTVYTSVPPYIGWIHQTIG 278
            |.||.|.||......|.....|:.||. ..|...|:|.|||.:|.:..||.:..|
Human   801 CQGDSGGPLSSVEADGRIFQAGVVSWG-DGCAQRNKPGVYTRLPLFRDWIKENTG 854

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33127	NP_787956.1	Tryp_SPc	41..276	CDD:238113	75/243 (31%)
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	73/240 (30%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	75/243 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920