Protein Alignment CG33127 and KLK7

DIOPT Version :10

• Sequence 1: NP_787956.1
• Gene: CG33127 / 318893
• FlyBaseID: FBgn0053127
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 74/291 - (25%)
• Similarity: 117/291 - (40%)
• Gaps: 60/291 - (20%)

  Fly     1 MLSPLFLLPLLALAGAAKLPHIQHLTLRDTEQVHAEIQPLIIDGYDVQG---VDNVP-----YLV 57
            :|.||.:| ||:||                         |...|.:.||   :|..|     :..
Human     5 LLLPLQIL-LLSLA-------------------------LETAGEEAQGDKIIDGAPCARGSHPW 43

  Fly    58 SLSLTRATYTHLCGASIIGKRWLLTAAHC-VDELRTFNG-DAVGTPVYAGIINRSNVTAAQVRYV 120
            .::|......| ||..::.:||:|||||| ::|.....| |.:|.       .|:....|...:
Human    44 QVALLSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD-------RRAQRIKASKSF- 99

  Fly   121 DFASTHRSFNGNAGSDNIALLHVSESFEYNARVQQIALPDINDDYSNKTAAAYGWGLTDPDGDEY 185
                .|..::.....:::.|:.::.....::.|:::.||. ..:....|....|||.|......:
Human   100 ----RHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS-RCEPPGTTCTVSGWGTTTSPDVTF 159

  Fly   186 SKELQYAFAPLLNSTGC----KELLPADAPLTAQQVCSQVKTCYGDGGTPLIYWPITGPAELVGL 246
            ..:|......|::...|    |:|| .::.|.|....|:...|.||.|.||:.     ...|.||
Human   160 PSDLMCVDVKLISPQDCTKVYKDLL-ENSMLCAGIPDSKKNACNGDSGGPLVC-----RGTLQGL 218

  Fly   247 GSWSYMPCGYANRPTVYTSVPPYIGWIHQTI 277
            .||...|||..|.|.|||.|..:..||:.|:
Human   219 VSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	62/245 (25%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	59/235 (25%)