DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33127 and prss60.2

DIOPT Version :9

Sequence 1:	NP_787956.1	Gene:	CG33127 / 318893	FlyBaseID:	FBgn0053127	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	244	Identity:	73/244 - (29%)
Similarity:	101/244 - (41%)	Gaps:	41/244 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 PYLVSLSLTRATY-THLCGASIIGKRWLLTAAHCVDELRTFNGDAVGTPVYAGIINRSNVTAAQV 117
            |:.|||...|  | .|.||.|:|...|:||||||:..:     ......||.|...:..|...:.
Zfish    46 PWQVSLQSPR--YGGHFCGGSLISSEWVLTAAHCLPGV-----SESSLVVYLGRRTQQGVNTHET 103

  Fly   118 -RYVDFASTHRSFNGNAGSDNIALLHVSESFEYNARVQQIALPDINDDYSNKTAA-AYGWG---- 176
             |.|.....|.|:|.|...::||||.:|.:..:|..::.:.|...|..||..|:: ..|||
Zfish   104 SRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSSWITGWGDVQA 168

  Fly   177 ---LTDPDGDEYSKELQYAFAPLLNSTGCKELLPADAPLTAQQVCSQV-----KTCYGDGGTPLI 233
               |..|.      .||....|::.:..|...| ....:|...:|:.:     .||.||.|.|::
Zfish   169 GVNLPAPG------ILQETMIPVVANDRCNAQL-GSGTVTNNMICAGLAKGGKDTCQGDSGGPMV 226

  Fly   234 -----YWPITGPAELVGLGSWSYMPCGYANRPTVYTSVPPYIGWIHQTI 277
                 .|      ...|:.||.| .|...|.|.|||.|..|..||...|
Zfish   227 TRLCTVW------IQAGITSWGY-GCADPNSPGVYTRVSQYQSWISSKI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33127	NP_787956.1	Tryp_SPc	41..276	CDD:238113	72/241 (30%)
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	70/238 (29%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	70/238 (29%)
		Tryp_SPc	34..267	CDD:238113	72/241 (30%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920